Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74804	Kin001-244	GSE92742	MCF10A	Human	24h	10uM	EID0431

Response Information :

Types	Number	Response transcription factors
Up-regulation	359	ZNF586; FOXO4; NFKBIB; HDAC6; ZNF419; TGFB1I1; TBP; SPI1; GLI2; PBX1; ETV1; ZNF211; PPARD; MBD2; PCGF2; OLIG2; ZNF304; SP140; USP21; SMAD2; FOXF1; BRWD1; RNF138; PBX2; ZNF500; PKNOX2; ZFY; CREB3L1; PAX5; TAF4B; HIC1; ZNF473; ZNF75D; ZNF623; NHLH2; MED14; ZNF446; IRF3; ZNF665; FOXO3; ZNF672; HINFP; SP110; CIZ1; POU2AF1; RBPJ; MAF; CSDC2; LOXL2; CIITA; ZNF778; MEF2C; BARX1; TCF21; RARA; SOX13; PRDM2; HSF4; ZNF202; RFX1; KAT8; HDAC4; IRF7; ZNF83; MBD1; KMT2A; NR3C2; KDM5D; ETV6; TEF; ATOH1; GABPA; ARNT; ZNF711; ZNF135; RNF14; ZNF787; ZNF580; WWTR1; ZNF532; ZNF460; FOXD2; CALCOCO1; ZNF573; TFCP2L1; ZNF444; LIMD1; HMGB2; SOX11; TGIF1; ZFPM2; PAX8; BPTF; CENPB; ZNF646; ZNF250; PRDM10; SOX5; FOXO1; MEF2D; TCF7L1; PITX3; KDM5A; ZKSCAN8; NR5A1; LYL1; ZNF391; ZNF835; TBX4; ZNF134; TCF4; MZF1; ZSCAN31; BACH1; PEG3; ZNF7; ZNF174; POU2F1; EBF2; FLI1; CBFA2T3; ZNF287; BCL6; WWP1; MAFB; ZNF506; ZNF324; GRHL2; ZNF329; MDM2; ADNP2; SIX1; ZNF549; ZNF175; CNOT3; CAMTA1; ZNF155; CDX1; RXRG; TCF7; YEATS4; NEUROG3; PIAS2; TBL1X; CAPN15; ZNF24; ZBTB14; ZBTB48; USP16; CREM; SUPT6H; NLK; ZNF141; NFATC4; PRDM4; CREB5; ZNF331; E2F4; UBE3A; SRY; ZBTB20; CHD3; ZNF345; E2F1; SOX18; NR0B1; RERE; TAF7L; POU4F1; RXRB; LHX2; ZNF124; EP400; ZNF688; TEAD3; IL16; POU6F2; ZKSCAN7; CHAF1B; VDR; MED25; FOXE1; ZNF154; NKX2-1; ZNF16; ZNF263; FOXI1; ZNF696; KLF3; CNOT6; FOXN3; TAF11; RBM14; MSL3; MLLT1; KLF11; NEUROD1; NFKB2; MLXIP; TRIM22; AES; ZNF34; ZNF248; ZNF177; NRL; ZNF45; NR2C2; EMX1; ZNF223; ZNF764; ZSCAN12; ZNF3; HESX1; FHL2; MYOG; RBFOX2; NCOA6; MEOX2; TCF15; NFATC1; KAT5; ZNF184; ZNF467; IRF8; SATB2; TDRD3; AFF4; ZNF112; FOXJ3; LITAF; HMG20A; PATZ1; HCFC2; SF1; ZNF606; MECOM; ETV5; FOXN2; TFAP2A; FOSL2; NR2F1; ZNF551; TAF10; ZNF614; HOXD10; SNAI1; BACH2; KDM4C; ZNF544; NCOA1; SIX6; POU4F2; OSR2; HEY1; TULP4; NFYA; TRAF6; CHD8; STAT2; TAF4; CARM1; UBP1; DYRK1B; PML; SOX10; SIAH2; NANOG; NFATC3; TCF3; SUPT3H; PRDM8; SMARCD2; ZFHX3; ZNF571; BNC2; TLE2; WT1; SIN3B; ZNF10; PROX1; KLF7; BCL11B; POU3F1; RREB1; ARHGAP35; FUBP1; KLF12; JUP; CHD7; HAND2; MXD1; ZNF165; HOXB13; YY1; SPIB; ZNF227; OVOL2; NHLH1; TADA3; ZSCAN18; ZIM2; PLAGL2; DEAF1; HOXD3; EHMT2; TFCP2; NCOR2; ZNF350; PHF1; ZNF292; CEBPA; TRIB3; FLNA; FOXJ2; HOXD11; ZNF217; ZNF611; KLF4; MTF2; NR2F2; NFIB; THAP7; CITED2; ZNF12; ZHX2; PAXBP1; NR1D2; SLC2A4RG; ZNF189; REL; GTF2I; KLF10; AHR; TAF9B; ZFP36L1; MAML1; SP100; RLF; NR5A2; AEBP1; ZNF423; CHD1; LZTS1; PPARGC1A; HLF; BCL3; NKX2-2; ZNF274; RBPMS; SMAD4; MNDA; IRF4; LEF1; SNAI2; SSX1; BASP1; JUN; EMX2; HES1
Down-regulation	330	MYC; PSMD9; RUVBL1; HDAC2; ENO1; TFDP1; CDK7; GMNN; ATF1; MYCBP; PCBD1; C1QBP; PRKDC; FOSL1; HMGA2; MED27; NFKBIA; COPS5; SIX2; DNAJC2; HDGF; MLX; SUB1; HMGN3; WDR77; ZNF593; TLE1; RHOA; RNF6; CBX6; TCEA1; DEK; ATF6; HMGB1; RBBP7; RAN; PEX14; PARP1; HOXD1; RUVBL2; TAF1A; CNOT1; ZFP36L2; PIR; SREBF1; TTF2; THAP10; ADRB2; NACA; MED6; ZNF302; MED13; PMS1; TRIM27; CDYL; RAD21; ZNF408; THRA; ESR1; CCNH; ZNF32; ARL2BP; DNMT1; CTNNB1; USP22; SND1; BRF2; NPM1; YBX1; THAP11; SOX15; HOXB7; RBL2; ELK1; ELK4; PPP1R13L; HABP4; RNF4; DNAJC1; TRIP6; SIRT7; XRCC6; ZNF576; TCERG1; BLZF1; BRD7; BATF3; MED4; RYBP; DDX5; DMTF1; TRIM29; JUNB; PPARG; BRD8; ARNTL; SSRP1; ZZZ3; SNW1; FOXC1; CERS6; GTF2IRD1; TRIM16; MSX1; PREB; VGLL4; RFC1; VEZF1; NKRF; ELK3; RBBP4; NCOA4; BANP; PSMC3IP; BTAF1; MAGED1; HOXB3; C1D; MITF; SMARCA5; ORC2; TCEB2; SP3; MAFF; AATF; REXO4; CDC5L; NR2C1; ZNF589; CCNE1; CRYM; TAF5; BTF3; SOHLH2; TRRAP; ID3; WHSC1; NFE2L1; ILF2; YAF2; ST18; PFDN5; ARID4A; HOXB2; URI1; ZKSCAN1; NR2F6; CCNC; MDFI; ASH2L; HIRA; TRIP4; JARID2; PSPC1; HDAC9; TOB1; TCEA2; EDF1; ACTL6A; NFKB1; TAF9; POLR2A; CDK8; HBP1; ISL1; MXD4; TCF25; APEX1; CTCF; PRRX2; ACTL6B; MTF1; ELF3; HOXB6; UBE2B; CBX3; HDAC1; SHOX2; ZNF426; ATF3; COPS2; THAP1; EWSR1; MED17; ZNF652; ID1; RFXANK; ZNF43; TRAK1; HNRNPD; HOXA5; SUMO1; GTF3A; HIVEP2; ERBB2; NR3C1; PTRF; TLE4; PLAG1; PEX2; SPEN; NFIC; PHIP; HLTF; NELFB; ATF5; PURA; CHD9; PITX1; HOXA1; SMARCE1; ZNF430; IRX4; BAZ1B; MXI1; CERS4; THAP4; PSIP1; SAP30; PA2G4; KDM5C; TCFL5; ZNF22; SIX3; ALX1; NR1I3; SALL2; CBFB; ZNF266; NFE2L2; JUND; HTATIP2; TP53; SSBP2; ZNF148; CREB1; ZFHX4; CENPF; CUX1; BAZ1A; CCNT1; CSDE1; HLX; ID2; ZNF140; ZMYND11; SUV39H1; TDP2; RXRA; MYRF; UBE2I; ATF2; HAND1; KAT2B; BRD3; ZIC1; BAZ2B; CLOCK; WWC1; ZBTB18; TOX; MAFG; CNBP; SMARCA2; ZNF14; TOX3; PITX2; GTF2A2; NAB1; REST; SOX9; PHOX2A; VPS72; BRD4; ZBTB24; STAT1; CALR; SERTAD2; KLF2; FOXF2; ZEB1; SOX17; PGR; EED; PAX6; ZNF117; CITED1; CHD4; PSMC3; ZMYND8; ZNF107; TERF1; MED1; HOXC4; ZNF443; HOXA10; ETS1; MEIS2; RNF111; MTDH; IFI16; ING3; BHLHE41; REPIN1; ARNT2; BBX; PLAGL1; ATF4; GATAD2A; NFE2L3; ZNF91; RFX5; BRCA1; DACH1; STAT3; CREB3L2; FOSB; CUX2; TCF12; NPAS2; TSC22D1; HOXC6; TBPL1; EGR3; HIC2; SOX4; PDLIM1; SMAD6; SMAD3; TWIST1