Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74737	Barasertib-hqpa	GSE92742	MCF10A	Human	24h	2uM	EID0431

Response Information :

Types	Number	Response transcription factors
Up-regulation	185	E2F2; SSBP2; SOX13; ZMIZ1; VGLL4; TCF4; PAX8; EHF; NFKB2; ZNF124; FUBP1; DAXX; NCOR1; ZNF195; ZNF273; E2F5; PRDM1; IRF6; ARID3A; ZHX2; CDK9; MSC; BRWD1; PCGF2; NFE2L3; DEAF1; ID4; TEAD4; PITX1; ETV5; GFI1B; SMAD7; MYRF; ZBED2; ESR1; IRF7; BAZ1B; KLF1; TAF6; KMT2A; TBX19; PIAS3; MDM2; ELF2; PQBP1; SIN3B; TSG101; ZBTB32; RNF10; CIZ1; ZNF131; MSX1; SRY; PCGF3; RB1; GATA1; TLE4; MAFB; AES; SAFB; PAX5; MEN1; IRF9; ZNF217; ZFPM2; SOX17; MBD2; CREBZF; VGLL1; ZKSCAN7; SUPT6H; GRHL2; LHX1; EMX2; ZNF24; RSF1; TRIM22; HMGXB4; ZNF787; SHOX2; UBE3A; SIX3; POU2AF1; ZNF506; ETV4; WIZ; ZFHX3; KAT2B; ETV6; TBL1XR1; MEIS2; ZNF83; LMCD1; ADNP2; OSR2; BACH1; HIF3A; PTRF; ZNF117; POU2F1; ELF5; KAT2A; SMARCA1; TFEB; BPTF; DLX4; TGFB1I1; SMARCC2; FOXA1; ZSCAN9; CBX7; EED; TAL1; RNF111; ZNF692; TRIM29; TAF10; AR; ZNF444; E2F8; CBFA2T3; ATF3; TRIB3; NLK; TBX3; ZNF423; SMAD4; SIX2; RBFOX2; ZNF107; HOXB7; ZNF266; MEOX2; EN1; CREB3L2; ZNF532; HDAC9; ERBB4; ZNF93; CEBPZ; CDK2; TBPL1; HIVEP1; ZNF12; TLE2; PRRX2; NPAS2; SMAD1; TCEA2; FOXI1; RARG; NUP62; JAK2; ATN1; INSM1; MEIS1; NCOA1; BNC2; DNMT1; CALR; PAXBP1; SOX11; AEBP1; RREB1; NEUROD1; FOXG1; SIAH2; POU4F1; PHF20; TXNIP; FOXL2; TFAP2C; SMARCA4; IRF4; HOXB2; BBX; TCF12; EZH2; VPS72; ARNT2; SMAD6; MNDA; HES1; ZIC1; LEF1
Down-regulation	207	ATF1; TCERG1; FHL2; FOSL1; ATF6; ZNF302; SUZ12; BRD2; CCNH; URI1; PTTG1; REXO4; MED1; DR1; YBX1; ENO1; CNOT1; CBX6; HDAC4; LOXL2; TLE1; TOX; MED27; CEBPG; HDAC1; NCOA6; ZNF268; SFPQ; RLF; ALX1; KLF6; FOXJ3; RBBP4; HNRNPD; KDM2A; ZNF783; RNF4; RUNX1; RFC1; NR1I2; CEBPB; PNRC1; DNAJC2; HEY1; SCAND1; ORC2; HMGN3; NR4A1; ARID4A; MYNN; ERG; ATF5; RBBP7; STAT6; ELK1; ADRB2; CCNA2; MED7; ZKSCAN4; TCF20; FLI1; CNOT6; SIRT2; ZBTB1; BMI1; SIM2; SP2; HMGB2; MSL3; FOSB; C1QBP; BCLAF1; RBPJ; THAP1; MTF2; HLTF; TCF7; ZNF200; KAT6A; PPARG; DDIT3; ZMYND8; SOHLH2; NRBF2; ZNF160; CAMTA1; ISL1; WHSC1; ELF1; ZNF10; TFCP2; TSC22D2; ST18; KMT2B; ADNP; PMS1; RBM39; TCFL5; CLOCK; ETS2; NKX3-1; HOXD1; DMTF1; HIF1A; ING2; ARID4B; BANP; RYBP; KLF10; CTBP2; ETS1; ZNF23; NFATC1; MAZ; SREBF1; ING3; ID1; NPM1; HOXA5; ZNF721; SND1; ZNF222; ID3; CBFB; ZNF281; BAZ1A; GATA3; MXI1; NR1H3; ZBTB24; NCOR2; PSPC1; RBL2; MED21; CSDE1; ZMYND11; MXD4; ERBB2; DEK; ZBTB38; CUX1; TAF9B; BLM; HMGB3; BASP1; SFMBT1; ZNF432; JUNB; BATF3; SP140L; ZNF410; PHF1; SMARCB1; ZNF45; TSC22D3; COPS5; HOXD11; PSIP1; RAD21; BRD8; ZNF189; RAN; HOXC4; FOXD1; NR2F2; ZSCAN31; NFE2L1; ZNF267; RBBP8; PEX2; BCL11B; CITED1; SMARCC1; ZNF529; E2F3; ZNF544; DNMT3B; YWHAB; BCL3; ENY2; NR2F1; NKX2-2; NR1D2; CREB1; ARNTL; MLXIP; KLF5; NFIL3; ZNF165; HOXC6; MECOM; EGR3; BRD4; TOX3; IRX5; PDLIM1; KLF2; SMAD3; HLF; SATB2; NR4A2; ASCL1; HOXC10; BHLHE40; PBX3; TOB1; TWIST1