Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74732	Saracatinib	GSE92742	MCF10A	Human	24h	10uM	EID0431

Response Information :

Types	Number	Response transcription factors
Up-regulation	90	ETV1; PBX1; PNRC1; SP110; FOXO3; NCOA2; MITF; FOXO4; ZNF665; BCL6; CALCOCO1; ZBTB20; OLIG2; ZNF195; LYL1; SP140; MNT; HOXA5; TP53; MAF; TRAK1; CREG1; SSBP2; PBXIP1; ELF1; TRIM22; PLAGL1; NFKBIA; BPTF; POU2AF1; TRPS1; HBP1; BACH2; CREB5; DDX17; BCL11A; MXI1; TCEB2; TLE1; ZNF33B; CEBPA; HDAC9; ZNF83; IRF9; JUP; MECOM; TFCP2L1; VPS72; RCOR3; ING4; CEBPD; IRF7; GATA6; ZKSCAN1; SMARCC1; NCOA1; ATF3; ZNF580; NFIL3; ZNF91; HMBOX1; LITAF; SALL2; PAX5; ZEB2; FOXO1; WT1; ZSCAN18; TCEA2; TGIF1; ZNF43; MEOX2; KAT6B; TOX; RXRA; BTG1; BASP1; STAT3; IRF8; ID3; FOXN3; HMGB3; TRIM29; MEIS1; MNDA; SATB1; ZIC1; PEG3; TWIST1; ARNT2
Down-regulation	87	FOSL1; HMGA2; SUV39H1; PTTG1; RBM14; TAF1A; CRY1; TBL1XR1; MYBL2; PSMC3IP; BRIP1; E2F1; FOXM1; WDHD1; POLR3F; NOC2L; HMGB2; SFMBT1; CCNA2; PPARG; FHL2; NKX3-1; MYT1L; WHSC1; TEAD4; ARNTL2; KAT7; DRAP1; AGO2; YEATS4; ZNF473; NFKBIB; TAF5; LMCD1; CHAF1B; CDK8; CCNH; BCLAF1; HOXB7; KLF6; TTF1; HMGA1; CENPF; MYBL1; BRCA1; CCNC; BAZ1B; EZH2; TGFB1; EGR1; TMF1; MTF2; HOXC6; HIVEP2; NR2F2; ZNF165; CDK2; FOSB; JARID2; CCNE1; FOXA1; ZBTB18; ILF2; E2F8; DDX5; KLF2; HNRNPD; AEBP1; SAP30; NRIP1; PSIP1; HIPK1; ELK3; NFIB; HOXC10; PIR; EGR3; DNMT3B; DNMT1; NR2F1; KLF4; BHLHE40; TBX3; GABPB1; MAFB; SOX4; HES1