Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74731	Azd-6482	GSE92742	MCF10A	Human	24h	0.08uM	EID0431

Response Information :

Types	Number	Response transcription factors
Up-regulation	164	NFKBIB; MDM2; VGLL4; HDAC6; PPARD; PAX8; MDM4; YEATS4; TGFB1I1; GABPA; CDK8; TGFB1; FOXE1; FOXF1; FOXN2; ZBTB20; MBD2; GTF2I; POU2AF1; TBL1XR1; NFATC4; CIZ1; IRF8; LHX1; RNF14; PAX5; TRIP6; ZNF419; NAB2; GON4L; AFF3; CAPN15; SPEN; NR2F1; TAF4B; DBP; MAFB; KLF11; SUPT3H; SP1; BRWD1; EGR1; MED25; OLIG2; ID4; SKI; SHOX2; PAXBP1; CBX4; EMX2; ZNF274; ZNF711; CDK9; ZNF587; ZBTB32; AIP; SOX13; ZNF83; ERF; WT1; CEBPE; ID2; MBD1; MKL1; SALL1; CBFA2T3; VDR; CREBZF; HHEX; CHD7; DDIT3; ZNF211; ZNF721; CBFA2T2; WWTR1; TCF3; OVOL1; EDF1; ZNF292; JUP; ITGB3BP; TRRAP; CNOT2; ZNF764; NRL; TCF7; MAX; TCF21; FUBP1; ZNF263; ZNF304; ZSCAN18; GATA4; BACH1; YAP1; GFI1; SCMH1; ZNF45; ZNF510; FOXD1; POU4F1; EHMT2; FLNA; ZNF135; TAF7; TAF11; VGLL1; HIRA; ZNF85; TFDP2; ZNF551; WWC1; LEF1; ZNF136; CNOT3; HOXB7; CTBP1; ZNF189; SMARCD3; ZNF573; TERF2; ZFP36L1; PIAS2; IRF7; TAL1; SP140L; EN1; SMARCB1; ZHX2; CITED2; HEY1; NKX2-1; BCL10; SOX9; RNF141; HLX; NFE2; TFEB; FOXI1; EHF; ZBTB16; ZIC1; TRIM22; CTBP2; HOXB6; TAF1D; SOX11; HMGB2; ZNF160; MYBL1; PEG3; PPARGC1A; BMI1; CD3D; ZBED2; MYCN; FOXG1; BCL11A; KLF9; HOXC10; MAF; TRIB3; MNDA; TFAP2C
Down-regulation	188	PSMD9; PCBD1; MYCBP; NFKBIA; HMGA2; SIX2; TBL1X; MDFI; MED6; PPP1R13L; SREBF1; ISL1; TSHZ2; ORC2; HOXD1; ZBTB18; PHF8; TP63; CNOT1; PMF1; CDYL; RYBP; URI1; DDX54; SAP130; HMGN3; CCNE1; DNAJC2; RAN; PIR; ZNF593; BRD2; BCLAF1; RBPJ; NR1H3; TRIM29; FOXA1; THAP10; ADRB2; CRYM; NCOR2; E2F5; RNF10; ESR1; JARID2; PLAGL1; CREBL2; NRBF2; PRRX2; TRPS1; SOX15; PBRM1; TULP3; FOXJ2; STAT4; CEBPB; ZNF140; LITAF; NAB1; CREM; NKX3-1; ELF3; MED1; SRF; PCGF2; CERS6; WDR77; LIN28A; IL16; POU5F1B; NFIC; PIAS1; TFAM; TOX3; BLZF1; PIAS3; TCF25; SMARCA1; HSBP1; MED21; KDM5D; JUND; SETD2; TCEA1; MAFG; ZFHX4; NR2F2; BRD4; ALX1; SMARCA2; MED13; TCF20; BASP1; ARNTL2; PEX2; PA2G4; HDAC7; CREB5; MEOX2; CSDE1; NCOA2; ASH2L; HOXB2; PSIP1; TOB1; NFE2L2; KLF5; PTTG1; RXRA; ZNF426; MLXIPL; DNMT3B; MYCL; SOHLH2; CDC5L; NFKB1; ZBTB7A; PFDN5; MLXIP; AR; ZNF23; BCL6; IRF4; ZNF266; CHD1; ATF4; ZFP69B; NFIB; ID1; TMF1; MXD4; CCNA2; RSF1; HMBOX1; ARID4B; WHSC1; ZNF432; SMARCA5; FOSB; ZMYND8; FOXO4; FOXM1; YBX1; PITX1; BANP; KAT2B; HNRNPD; BCL3; CHD9; NR4A3; TDP2; ENY2; COPS5; SSBP3; PHIP; FOXC1; GTF2A2; HMGB1; DDX5; CLOCK; NFAT5; NR4A1; BAZ1A; ZNF331; CREB1; INSM1; CUX2; HIVEP1; PBX3; GABPB1; STAT3; LPIN2; TAF9B; MAGED1; TCF12; YWHAB; PHF20; VPS72; CNBP; TXNIP; NFIL3; EGR3; OSR2; SMAD3; BHLHE41; KLF10; KDM5B; RFX5