Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74729	Azd-6482	GSE92742	MCF10A	Human	24h	2uM	EID0431

Response Information :

Types	Number	Response transcription factors
Up-regulation	135	SOX2; TBP; ETV1; PAX8; MDM2; TCF21; WWP1; NR2F2; BRIP1; NFATC4; ZHX2; ZNF623; TGFB1I1; BCL6; HDAC4; SRY; ID4; NR0B1; YBX2; AES; EN2; OLIG2; CERS6; EWSR1; EGR1; ZNF711; MLXIP; NEDD8; WT1; FOXE1; KAT8; AFF4; MAP3K10; YAP1; BAZ2B; TGIF1; MAX; TRIM16; VEZF1; EHMT2; SLC2A4RG; HHEX; CALR; PMS1; SAFB2; ZBED2; SFPQ; ZBTB1; RARB; AIP; SIX1; LHX1; PBX1; HOXD3; MBD2; SUPT3H; NCOA6; MAFG; ING2; THAP10; ZNF83; AFF1; ZBTB25; HOXD10; TAF11; IRF7; WWTR1; MED20; PROX1; TCF4; IFNB1; NR2F1; HMGN3; PHF1; ZNF281; TRIM22; ZNF12; ZNF239; HDAC9; HSF2; HOXD11; ATN1; CHD1; CREG1; MYB; ZSCAN31; GRHL2; ERBB4; WWC1; POU2AF1; ZNF292; GATA4; ZNF117; EPAS1; HMGB2; PATZ1; NR1H4; FOXA1; MED13; E2F3; BRPF1; FLNA; SALL1; ASCL1; TLE2; ZNF467; ZFP36L1; SMAD1; NEUROD1; MECOM; SMARCD3; ZFPM2; LEF1; ZBTB18; CTBP2; YWHAB; PHF20; PEG3; SMARCD2; PAX5; PBX3; FOXI1; RBPMS; SATB2; KDM5B; JUN; MNDA; FOXG1; CHD7; AEBP1; SOX11; NCOA3; TBX3; TFAP2C; GTF2A2
Down-regulation	152	FHL2; ATF1; HMGA2; NFKBIA; TFDP1; TGFB1; RHOA; PPP1R13L; ZBED1; SIX2; ENO1; NACA; TCEB2; URI1; RBL2; RBBP4; MED6; WDR77; SMAD5; ZNF426; CEBPB; ZFP36L2; ATF4; ZBTB16; TCEA2; ZNF224; TFDP2; MSX1; ZNF134; RFC1; SMAD7; PFDN5; PTRF; CEBPG; RUNX3; NELFB; MED1; KLF3; ATF5; PLAGL1; NCOA4; XRCC6; ZEB1; KAT2B; NR1I2; BRD7; ZNF532; RAN; IRX4; EDF1; TP63; IRF2; ARL2BP; CTR9; FOXC1; CCNE1; ISL1; MED4; NPM1; NFKBIB; KAT7; ALX1; HLX; JUNB; HMGB1; ILF2; CTBP1; TRIP4; EYA2; NFKB1; BLM; ZNF14; TAF12; SSRP1; SREBF1; TRPS1; TEAD4; TBX1; ZNF430; INSM1; ARNTL2; SNAI2; HIC2; BAZ1B; RORA; HOXB6; ZNF432; ZNF91; BTF3; SUB1; ZNF266; MXI1; VDR; HDGF; IRF1; RXRA; BATF3; CSDE1; LITAF; DNAJC1; ZNF45; FOXF2; ESR1; ZNF227; ZBTB38; CREB3L2; PEX2; NR4A1; AHR; ZNF32; KLF2; HOXD1; TCEA1; ZNF551; PQBP1; RCOR1; HBP1; ID3; MYBL1; PIR; ZKSCAN1; APEX1; TFCP2; SOX10; JAK2; RNF141; HLTF; BHLHE41; NFAT5; FOXD1; IFI16; REL; DLX2; HOXB2; TOX; PURA; NPAS2; MYCL; TRIM29; ID1; BCL3; CNBP; KLF4; BRCA1; TXNIP; VPS72; ZIC1; BASP1; STAT3; TOX3; MEIS1; TWIST1