Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74698	Vemurafenib	GSE92742	MCF10A	Human	24h	2uM	EID0430

Response Information :

Types	Number	Response transcription factors
Up-regulation	180	SUV39H1; HOXD1; PAX8; STAT3; AR; MZF1; WT1; TAF5L; DLX5; SPDEF; ISL1; TXNIP; HOXD3; FUBP1; ZFPM2; BNC2; DAXX; CITED2; MEIS2; ZNF248; TFAP2A; NFE2L2; OSR2; PHIP; NFE2L3; ZNF444; RBFOX2; ARID5B; PIAS1; NR4A2; CREB3L2; EP300; HIRA; RORC; ERBB4; ZNF512B; DLX4; ZNF180; MNDA; CNOT6; ZNF711; EYA1; GATA2; ZEB1; THAP10; ZNF273; HIC2; ZNF253; INSM1; MED17; MXD4; GTF2I; HOXB2; NCOR1; NFYC; ZXDC; MED12; SATB1; ETV5; CREM; TRIM28; NR4A1; CSDC2; AES; NFKB2; HBP1; ZZZ3; ZNF331; JAK2; RARG; ZNF12; ELF3; NR2F1; TRIP4; HIPK1; ZNF93; RREB1; MYRF; CIZ1; HMGXB4; PATZ1; KAT8; WIZ; ZNF611; RERE; TEAD4; ZNF629; CBX7; TCF4; CRYM; PRDM10; ZNF264; MAFB; MAML1; FOXL2; ESR1; ZIC3; BHLHE41; ZNF33B; ZNF43; IRF5; SMAD4; ZNF721; ARHGAP35; AFF1; ITGB3BP; PKNOX1; ZNF710; PRMT2; SALL1; TRIB3; TAF12; NFATC1; SOX13; ZNF665; PAX6; ZBTB16; ZNF551; CBX4; NFX1; CUX2; ZBED1; ID4; RBPMS; KLF2; SMARCA1; DEAF1; BCL11A; CARHSP1; MEIS1; SUPT6H; URI1; RBBP8; KDM5B; MYCL; NPAS2; TSC22D3; RB1; PCGF3; TCEA2; ATF7IP; ZNF160; ARNT2; TBX3; TFEC; TFAP2C; ZNF423; NKX2-1; TRIM24; ZHX2; ZNF189; GTF2F1; HLF; PSMC3; BHLHE40; ZIC1; SIX3; ST18; HMGN3; ARNTL2; PLAGL1; LYL1; ATF3; MAF; CREB3L1; PIR; CHD9; DMTF1; NR2F2; TRIM22; HHEX; SOX11; ZEB2; JUP; SHOX2; MYBL1; PEG3; FOXG1; PBX3; GMNN
Down-regulation	184	ATF1; ATF6; TLE1; HEY1; CDX2; CBFB; MTA2; CALR; TP53; VGLL4; YAF2; E2F3; PPARG; ID3; RBBP5; HOXB7; NRBF2; TADA2A; HCFC2; TMF1; HOXA5; CCNA2; VDR; KLF12; ZNF165; PMF1; POU3F2; SAFB; TCERG1; NR2E1; BRD8; ZNF302; GABPA; ADRB2; ZNF292; MSL3; IKZF3; TFAM; ZNF177; NR1I2; TOX; AATF; PDLIM1; HOXA1; SFMBT1; TERF2; MYB; ELF1; TFEB; PBRM1; MDM4; HIF1A; NR1D2; ZHX3; SMAD5; BRCA1; SAP30; SUB1; CHD7; ZSCAN12; ZMYM2; ZBTB11; ARNTL; CARM1; COPS5; PPARGC1A; ZSCAN18; DDIT3; CDK9; PHF8; MSX1; EED; ASCL1; HOXA7; MED1; DRAP1; CNBP; HIVEP2; NONO; SOX12; CRY1; ECD; PA2G4; TSC22D4; HSF2; BANP; NFAT5; CREBL2; ZNF211; LEF1; ZNF646; ZNF23; TSC22D2; SMARCE1; PURA; TAF10; KLF9; YBX3; YBX1; SMARCC1; SNW1; POU3F1; ATF5; WHSC1; GABPB1; MXI1; BMI1; TOB1; CDK8; FOXN2; PTTG1; HMGB1; TEAD1; HIPK3; SUZ12; RBBP4; FOXO1; TAF9; ZNF410; SREBF1; ZNF143; JARID2; FOSL1; SOX4; PEX2; VPS72; VEZF1; ZNF266; TFCP2L1; MED4; ZFX; MED24; BCL11B; CCNC; ELK3; LOXL2; NUP62; FOXD1; ZSCAN16; ZNF226; BTG1; HMBOX1; TOPORS; GFI1; RFX7; DDX5; TCF7; ING2; ASXL1; ZFP36L1; ZBTB38; HMGA1; MEOX2; HOXB6; CEBPG; ZNF529; ILF2; INSR; HTATIP2; SKI; RORA; JUND; HMGB3; ELF5; HDAC2; PBX1; SOX10; MLXIP; RAN; SAP18; EGR2; POU2AF1; ZSCAN31; SMAD3; AIP; KLF10; TRIM16; SMAD1; PAX5; ZNF281; ID1; RELB; GATA3; E2F2