Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74697	Vemurafenib	GSE92742	MCF10A	Human	24h	10uM	EID0430

Response Information :

Types	Number	Response transcription factors
Up-regulation	101	SSBP2; MNAT1; TSC22D3; XBP1; ATF4; NCOA1; SOX15; PIAS3; ZNF446; FOXO4; RNF4; ASH2L; CSDC2; HMGA2; CREG1; PSPC1; TERF1; ETV1; TOB1; EZH1; MAGED1; TRIB3; ELK1; ELF1; APBB1; NR4A1; PGR; WHSC1; COPS5; IL16; DDIT3; ZSCAN18; KDM4C; ARID4A; PRRX2; LMCD1; TRIP4; ERBB4; HMG20A; NFATC1; SIX1; TCEA1; NR4A2; ASCL1; FOSB; ELF3; FOXD1; PDLIM1; HMGB3; EGR1; TCF15; CTBP2; BBX; TULP4; TGIF1; ARNTL; CREB3L1; NCOR1; NPAS2; BTG1; GATA6; HLTF; ZBTB16; SOX10; TSG101; JUP; POU5F1B; SMARCA2; PSIP1; SMAD5; SNAI2; KLF2; ZNF516; MYCL; NPAT; CITED2; FOXO1; OSR2; HSBP1; DPF2; JAK2; KLF5; TDP2; HIC2; CREB3L2; MED1; EGR2; ZMYND8; ELF5; AEBP1; ZNF532; CHD7; SPIB; IFI16; TOX3; PBX3; ATF3; ZEB2; EGR3; MYBL1; PSMD9
Down-regulation	119	TP53; TFAP2A; HLX; REL; LHX2; THAP7; FOXF2; TAF11; NEDD8; HMGA1; MYBBP1A; ZNF268; ZNF232; ZNF292; HEY1; DLX2; PHOX2B; TGFB1; POLR3F; ZNF136; TTF1; ZNF302; DNAJC2; DEAF1; HLF; EMX2; PEG3; ZNF394; ZNF3; NPM1; ZNF32; NFKB1; RORA; ZNF354A; PHIP; ZSCAN31; HOXB13; MED23; ZFP36L1; HHEX; CCNE1; SMAD1; ZNF557; MEOX2; SFPQ; ZNF573; TCF4; RBM39; ZNF512B; FOXG1; CDK9; GTF3A; ZNF184; EHMT2; ZNF117; ZNF43; SOX18; JUND; ZNF281; RUNX3; HOXB6; RREB1; ZNF195; PAWR; CARM1; E2F3; DEK; CTNNB1; ZEB1; PLAGL1; TRIM27; NR2F1; TFEC; TLE4; NFIL3; COPS2; GTF2F1; ID3; SKIL; MXI1; TFAP2C; ILF2; TGIF2; SOX11; CRY1; ARNT2; SREBF1; FOXA1; PSMC3; RNF138; HDAC2; SCAND1; ZNF423; HOXB7; ZFPM2; AHR; YBX1; ZNF91; FOXM1; LEF1; SIAH2; EN1; MSX1; MECOM; CD3D; FOXF1; ELK3; SMARCA1; C1QBP; SOX17; MKL2; MNDA; AES; RNF141; NFIB; POU2AF1; SUZ12; ESR1; MEF2C