Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74695	Alvocidib	GSE92742	MCF10A	Human	24h	0.4uM	EID0430

Response Information :

Types	Number	Response transcription factors
Up-regulation	219	PAX8; HOXD3; TSC22D3; TLE1; HOXD1; VGLL4; TFAP2A; ATF3; MAX; SETDB1; FOSB; ZKSCAN4; ZNF211; TXNIP; KLF4; HLX; RLF; ELF4; ESRRG; KLF11; PRDM2; TAF11; DACH1; SOX13; ZNF7; ZNF665; FOXJ3; TOB1; ING4; HBP1; MAK; ZNF778; TCF7L1; HIPK1; SETD2; ST18; LIN28A; KDM4A; WWC1; EZH1; CEBPG; EMX2; E2F3; FOXO4; VEZF1; DDIT3; OVOL2; ZNF419; HIRA; CBX2; ZNF117; ZNF835; ZNF83; PPP1R13L; ZNF93; ZMIZ2; ZNF304; ATF2; RYBP; HDAC4; HIPK2; ZSCAN12; RNF4; ZNF669; ZIC3; SUPT4H1; GON4L; EP300; CSDC2; CIR1; BIRC2; ZBTB43; SP2; NFE2L1; ZNF212; ZNF202; PKNOX2; ZMYM2; ZNF24; ZNF467; ZNF85; FOXN3; KAT8; MEIS1; CBX7; NFRKB; ZNF423; ZNF264; SALL2; TSC22D1; ZBTB17; NANOG; MITF; BHLHE41; ZNF250; IRF9; CBX6; CDIP1; SOX17; ZNF43; ZNF141; FOXA2; TRPS1; ZNF34; TRAK1; ZNF573; HINFP; KLF3; NFYC; TCF7L2; MNT; MECOM; REST; TFAP2C; TRIM29; ZNF623; EHF; ZNF165; NR2C1; ERBB4; SUPT6H; TRIM33; ZNF426; BCL10; SIN3B; MAFG; ARNT; HOXB5; OSR2; KDM5B; VPS72; NR2F1; CDYL; ZSCAN9; ZNF239; ZNF44; TAL1; BCL6; CITED2; ZNF529; PCGF3; WT1; YBX3; ZBTB20; KLF7; ZNF273; ZXDC; NCOA4; SP140L; TWIST1; ARID5B; MEF2C; CUX2; ZFPM2; REPIN1; TCF21; ELF3; TDP2; ZSCAN16; KLF5; ZFP36L1; GATA6; ZNF544; BNC2; HDAC9; SOX10; FOSL2; MNDA; IRF1; COPS2; RCOR1; ZNF195; SOX2; HIC2; ZNF91; TBPL1; EHMT2; PBX1; ZNF667; FOXO1; TCEA2; ZBED2; ZNF160; JUND; SNAI2; ARNT2; RING1; POU5F1B; JUP; NPAS2; RSF1; ZNF611; KLF10; IRF6; ESR1; FOXK2; PCGF1; ZNF512B; ZNF415; MAFB; PTRF; SAP18; ETS2; KLF9; ID1; AHR; TCF4; ID4; KLF6; IRF8; NFE2L3; PSMC3; SHOX2; KDM5D; MLXIP; ZNF652; MYRF; RBPMS; HIF1A
Down-regulation	204	PARP1; CCNA2; HMGA2; MYBL2; MAGED1; ACTL6A; ATF1; CBFB; GTF2A2; TP53; PPARG; RBM14; MNAT1; ORC2; EZH2; IKBKAP; BRCA1; DNAJC1; BCLAF1; STAT6; RBBP4; KAT6A; BAZ1A; MXD4; MEF2D; ATF5; HMGB1; THAP7; TCFL5; TFCP2; ECD; PBXIP1; CCNT1; PCBD1; TRIM32; WDR77; BMI1; WDHD1; TCF20; RBBP7; TAF10; TRIM28; HOXA10; BATF3; ZNF205; PITX2; HOXA1; RBL1; PSMC3IP; DLX2; FOS; RFX5; CENPF; HOXC4; SFMBT1; CARHSP1; STAT5B; HOXA7; CALR; HOXC10; MBD4; EGR1; CBX5; IRF2; ZBTB38; TRRAP; ETV5; HOXC6; IRX5; BCL11B; RUNX3; YAF2; ZNF574; PRDM1; TMF1; NFKBIB; PMS1; PTTG1; EGR4; BNC1; PSIP1; CREB5; TLE4; MEOX2; CIC; PMF1; BRCA2; IRF4; FOXD1; ERBB2; PSPC1; PHF8; SOX15; PA2G4; CITED1; NFIC; BLM; MAZ; POU2F2; TOX3; NPM1; CHAF1B; HES1; HSBP1; SMARCD1; EED; ETV4; SFPQ; HNRNPD; HDGF; SP140; STAT1; SSRP1; REL; DDX54; ARNTL2; PAX5; NFYA; VDR; TSC22D4; GABPB1; MAML1; IRF3; NR1H4; PURA; ISL1; KLF2; ERCC2; C1QBP; SOX4; MED13; GCFC2; KDM4C; CARM1; LPIN2; BATF; JUNB; SMAD7; ARID5A; IFI16; MGA; YWHAB; SIX2; SIAH2; ASCL1; PDLIM1; CRY1; RAN; ZNF32; SLC2A4RG; FOXA1; POU2AF1; TGFB1; BAZ2A; EYA1; PITX1; SMAD1; STAT4; ZNF124; MSX1; CHD9; SCAND1; POLR2A; RB1; WWTR1; TAF9B; TAF1D; SUB1; URI1; SMAD5; CNOT1; SPIB; RBM39; MED1; NFAT5; HLTF; SOX11; ELK3; AES; CD3D; ILF2; ETV1; BRD3; PRMT2; TRIP6; FOXC1; SMARCA4; HMGB3; TFDP1; NAB1; SMARCA2; NR0B1; CTNNB1; RBL2; POU4F1; SMARCD3; AEBP1; TSC22D2; HHEX; NR2F2; TBL1X; SMARCA1; EGR3; ID2