Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74694	Alvocidib	GSE92742	MCF10A	Human	24h	2uM	EID0430

Response Information :

Types	Number	Response transcription factors
Up-regulation	317	PPARD; HDAC6; TFAP2A; NFATC4; ID4; IRF9; ZNF589; SSBP2; ZNF93; PRDM14; TBX2; SALL2; TCF7L1; LHX3; EGR1; ZSCAN18; L3MBTL1; RARG; HOXD1; HOXB1; ZNF75D; DLX5; CDX4; TTF2; ATF3; HDAC9; CREM; ZFPM2; ZNF835; HBP1; LEF1; ZNF43; MZF1; SPDEF; AEBP1; PRDM12; HESX1; RORC; VGLL1; HOXA3; HOXD3; SSX1; WNT4; BNC2; MEIS2; CDX1; ZNF141; BARX1; ZNF665; SOX13; MED12; TP53; CDIP1; SUPT3H; MECP2; NFE2L3; ZNF85; CALCOCO1; HIPK2; SOX2; FUBP1; ARID5B; CSDC2; ZIC3; ING4; WT1; PROP1; VPS72; PAX8; ZBED2; ZKSCAN4; LOXL2; ZNF264; STAT4; ZNF586; EMX1; POU5F1B; TERF1; ZNF506; ZNF91; THRB; CREB1; SOX17; ZNF423; HSF4; TCF21; ZNF444; TBX21; ZNF816; CRX; LIN28A; ZNF331; SNAI1; NR5A2; ZNF253; FOXH1; PRMT2; NR0B2; MED13; FOS; PRDM1; KDM5C; RBPJL; HOXA6; ZNF467; TWIST1; ZNF154; ZNF682; CREBL2; MED14; PBX3; LZTR1; ZNF654; ZBTB7B; OVOL1; CDK2; DACH1; ZNF671; BACH2; NFE2L2; CSDE1; MYRF; CNBP; CBX7; BRWD1; THRA; CRTC1; MEIS1; GON4L; ETS1; NR5A1; NANOG; ZFHX2; ZEB1; MYCL; ZNF688; ID3; MAP3K10; ZSCAN2; PBXIP1; TDRD3; KDM4C; CAMTA2; NHLH1; MXI1; HAND2; ZNF611; TGFB1; BHLHE40; TCEA1; EP300; NR4A2; TCF4; AR; ZNF701; TBX19; BCL11A; ZNF551; NR4A3; CREB3L2; KLF3; RAX; CERS4; HIC2; RFXANK; TRIB3; SUPT5H; ZBTB44; SOX21; SOX3; TBX1; MXD4; HEYL; SSBP3; ACTL6B; GLI3; CEBPE; MED15; ATOH1; TCEA2; EMX2; POU2F2; SHOX2; CHD3; ZNF623; EHMT1; HMBOX1; ZNF117; IKZF1; GLI2; SIN3B; DLX4; REL; ERBB4; BBX; KLF13; PHF1; PRDM2; SMARCC1; ST18; PRDM10; ZNF224; NHLH2; NCOA2; HIRA; TAF4B; ZNF710; URI1; FOSB; TULP3; ZNF500; IRF7; CNOT3; GCFC2; SMAD7; PKNOX2; STAT2; ZNF768; SOX5; TCF3; CBX2; ZIC1; SND1; ZNF587; ZNF562; PCGF3; KAT2B; EPAS1; CBX4; KLF15; SCMH1; SRY; ZNF711; CTNNB1; ATN1; ETV4; SPI1; LITAF; NKX3-2; RBFOX2; RERE; ZNF580; ZHX2; SRCAP; DBP; KLF7; NR4A1; PBX1; ZNF304; ZKSCAN1; NR1H2; JUNB; POLR3C; HOXB5; TSC22D3; SP140L; DAXX; ZNF532; CIZ1; BRD7; ZNF140; ZNF257; CUX2; MITF; MYBL1; BHLHE41; RB1; ARNT2; MYCN; FOXE1; PDLIM1; KLF11; ZNF195; FOXF1; SUPT6H; ZNF273; IRF6; YAP1; ARID3A; ZNF667; ZNF74; CUX1; PEG3; MAFF; PFDN5; TRIP4; TFDP2; SREBF2; ARNT; TEAD3; PSMC3; GATA1; NFE2; ESR1; FLI1; MECOM; SMARCA1; ZNF354A; SALL1; NFATC3; ZBTB20; TDP2; CHD7; SIX3; IRF8; ZNF83; MAFB; TGIF2; ZNF415; NR2F1; NEUROD1; ID2; ZFP36L2; ZNF512B; TRPS1; KLF9; HIF1A
Down-regulation	411	CCNA2; FHL2; SUV39H1; ATF1; TCERG1; CRK; CDK7; USP22; NFKBIA; PUF60; FOXO3; RUVBL2; SAP30; HOXA10; TBP; RBM14; TLE1; ADRB2; MYC; ZNF672; RHOA; ARID4B; SFPQ; TRIM32; TCF20; IKBKAP; ZMYM2; CEBPZ; NEDD8; VGLL4; ATF6; BRD8; NRIP1; ERBB2; MED6; HMGB2; SNW1; MAX; BAZ1A; NRBF2; BCLAF1; CCDC59; TRIM28; MLX; HOXA5; SMARCE1; CENPF; TFAM; RFX5; AATF; SP3; SNIP1; SETD2; RCOR1; ELF1; ADNP; ECD; MED1; PSPC1; NUP62; CENPB; ASH2L; NCOA6; HDAC7; SAFB2; PPRC1; PPARG; MED23; MED17; APEX1; BRPF1; NCOA4; UBP1; ZBTB11; HSF2; E2F6; KDM5A; ELK3; ZSCAN5A; RNF4; GABPB1; UIMC1; MED27; CTR9; PHF20; RBBP5; ZNF292; DDX54; YAF2; NR2F2; ORC2; XBP1; HMG20B; EZH2; ERCC3; HCFC2; RNF6; RBBP4; ZBED4; NCOR2; PAXBP1; DNAJC1; BANP; AGO2; ZNF384; ABL1; PRDM4; TAF4; ZFP64; TCFL5; RAN; ZNF148; KAT5; TRIM27; VEZF1; DEK; ZBTB7A; ZNF473; CEBPG; IRX5; CTCF; NFKB1; ING2; YWHAB; MTDH; CNOT1; TBL1XR1; FOSL1; HOXB7; TXNIP; PPARGC1A; PA2G4; ATF7IP; ZNF574; PBRM1; NELFB; SAFB; UBE2I; CRY1; THAP1; TMF1; PSMC3IP; HNRNPD; KDM2A; PTTG1; PITX1; PLAGL2; POLR2A; TSC22D1; SUB1; SIX1; PIAS2; PMS1; ARID4A; REXO4; TAF1A; BRF2; TAF5; ZBTB24; TRAF6; ZNF23; HMGXB4; BAZ1B; POLR3F; RNF138; EWSR1; CCNC; SOX9; KMT5A; IRX4; MAGED1; DDIT3; BMI1; TAF10; TTF1; IKZF5; ZNF84; ZNF14; NFIL3; RBBP7; PHIP; BTG1; HSBP1; MEF2D; TADA2A; ADNP2; CDYL; NONO; PMF1; KAT7; NKX3-1; MED24; NFIB; ZNF410; HMGB3; KLF2; GMEB2; PHF2; HOXA7; FOXJ3; YBX3; CDK8; HDGF; ZNF764; STAT6; GABPA; CEBPA; ZNF639; KLF6; FOSL2; MED7; ATF4; ZNF432; KAT6A; MNAT1; SMARCD2; WHSC1; PCGF2; SIRT7; RARA; EDF1; MTA1; ZNF443; KDM5B; KAT8; DDX5; MNX1; SUZ12; ZNF266; RBL1; ZNF263; HOXC6; NPM1; ELF2; EED; CBFB; SSRP1; C1D; STAT3; TEAD1; SMARCA2; TAF1D; ZBTB40; SIAH2; NR1D2; UBE3A; NFYA; THRAP3; YBX1; HIPK3; RNF111; TBL1X; BRCA1; SF1; MDFI; USF2; DPF2; ZNF236; SFMBT1; ZNF184; PATZ1; ZSCAN12; MYOG; FOXN2; USP21; FOXA1; LPIN2; REPIN1; MED21; MTF2; SMAD5; CDK9; HOXC10; ZNF692; ZNF302; ETS2; HOXA1; ABT1; ZHX3; DNAJC2; RELA; USP16; CHD1; PHF8; BCL6; ING1; RFX7; SMAD4; GTF3A; HDAC4; HEY1; MYF6; WDHD1; SETD3; ZBTB16; MSX1; ZNF146; NFAT5; ARNTL; ZNF24; CREB5; MYNN; PIR; ZNF226; SMARCD3; CASZ1; IRF2; SIM2; ZNF337; BRD2; ZBTB1; KLF10; AFF4; PCGF1; ZNF593; TOB1; PURA; BTAF1; TRIM16; ZNF32; ZNF227; BLM; MAML1; CNOT2; RUNX1; RREB1; BCL3; EN1; BRD3; ZBTB18; PRPF6; TRIP6; TP63; ASXL1; ZNF529; MEOX2; MXD1; SOX4; ILF2; SIX2; MEF2A; WWTR1; TSC22D2; RBPJ; ZFX; KLF5; HCFC1; ZMYND11; SMAD1; MNDA; FLNA; AFF1; ZNF267; ENO1; SPEN; BTF3; RXRB; SMARCA5; KMT2A; HDAC2; FOXM1; ISL1; SREBF1; HOXC4; UBE2B; ELF5; JARID2; MED4; REST; KLF4; PITX2; FOXC1; ZNF143; CHD9; PSMD9; TERF2; HDAC1; ASCL1; HES1; MLXIP; TSC22D4; NFYC; ZNF112; FOXG1; TBX3; BATF; ARNTL2; E2F8; RUNX3; TOX3; RYBP; ZNF282; SMAD2; ETV1; ZNF281; RNF141; RBM39; CEBPB; JUND; TRIM29; ZNF107; DMTF1; HLF; SCAND1; MKL2; HOXB6; ERG; GATA3; POU2AF1; RELB; BASP1