Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74668	Torin-2	GSE92742	MCF10A	Human	24h	2uM	EID0430

Response Information :

Types	Number	Response transcription factors
Up-regulation	137	FOXO4; PPARD; ADRB2; TSC22D3; HOXD1; ZNF358; MNT; FOSB; RNF10; FHL2; HOXD3; FOXD1; MECP2; CREG1; PNRC1; PDLIM1; MZF1; KLF7; HMGA2; HDAC6; TCF15; ZBTB7A; PRDM2; EP400; XBP1; ZNF23; KDM4C; HBP1; EVX1; PRDM14; ZNF302; CHD4; NCOR2; ZNF646; MLXIPL; MAFG; EHF; ZNF250; CEBPE; PPP1R13L; CNOT1; DDX17; TRAK1; CALCOCO1; FLNA; TSG101; KLF2; ZNF410; TCF7L1; TEAD3; CDYL; TGFB1I1; ZNF423; EGR1; LIN28A; SCMH1; CNBP; HMBOX1; CAMTA2; STAT6; BRD4; ZSCAN18; SETDB1; SND1; JUND; TSC22D4; ELF4; DDIT3; ATF4; CIC; ZBTB43; YBX3; KDM5B; ARHGAP35; EZH1; KLF4; KLF10; RYBP; HIVEP2; SUPT3H; KLF6; LMCD1; CSDE1; POU5F1B; NR2C1; BCL3; TWIST1; SMAD6; KLF5; MSC; DBP; TGFB1; FOXJ1; KLF9; ST18; ZNF415; IRF1; NPAS2; GATA6; VPS72; TCF21; PHF20; ZNF33B; BTG1; FOXK2; CALR; MTA1; MYRF; NFE2L1; SMARCD3; ZMYND8; SMARCA2; ZNF83; ASXL1; NR2F1; RBL2; ZNF165; FOXG1; ZBTB16; BRD2; AEBP1; ATF3; MXI1; EYA2; HMGA1; SNAI2; DMTF1; ZNF532; SIAH2; ZFP36L2; EGR3; KDM5D; TRIM29; ARNT2; BHLHE41; PSMD9; ID1
Down-regulation	151	ATF1; MYBL2; CCNA2; SUV39H1; TP53; GTF2A2; CREB5; RFX5; ZNF692; TAF1A; ZNF14; TAF5; IKBKAP; ZNF148; MTDH; ENY2; HOXA10; RBM14; ACTL6A; TFAM; ZNF124; CENPF; TRIM32; PARP1; BCLAF1; NRIP1; C1D; ZNF764; SMARCD2; TFEC; MTF2; WDR77; DNMT1; RBBP5; EZH2; ZNF45; CBFB; THAP7; ZNF468; HEY1; SAP30; DRAP1; C1QBP; RBL1; TGS1; ZNF136; IRF8; ZNF557; PSMC3IP; BRCA1; PIR; MED7; THAP1; ZBTB18; WDHD1; SMAD1; ZNF180; PREB; SP3; HMGXB4; SSX1; PRKDC; YWHAB; CCDC59; IRF2; HSF2; ZNF528; ZNF200; ZBED4; EED; TFCP2; SUB1; PRRX1; SUZ12; IKZF5; ECD; ANKRD1; ZNF267; PTTG1; MSX1; WWTR1; ITGB3BP; MYB; VDR; ETV5; CDK8; RNF6; SMARCA4; SMAD5; SMARCD1; TAF11; YAF2; NFE2L3; NCOA2; ZNF226; KAT7; ZFX; PITX2; HOXA7; HOXB7; HIRA; TRIM28; ZFPM2; SFPQ; ETV1; BCL6; INSM1; SALL1; E2F8; MBD2; YEATS4; MEIS2; HHEX; HIC2; ZEB1; MYCBP; BNC2; NR2F2; HOXC6; HOXB6; SP140L; CITED1; ZNF430; MITF; MED1; PEX2; CCNC; AIP; TCF7L2; MYBL1; ASCL1; AHR; ELK3; ZNF107; HLTF; IFI16; ZNF512B; SHOX2; PITX1; TCF4; EN1; NAB1; SOX11; FOSL1; PAX5; OSR2; TRIM16; LEF1; MEF2C; DACH1; GMNN