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Overview Perturbagen Expression Profiles Transcriptional Responses
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Overview Perturbagen Expression Profiles Transcriptional Responses
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Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID74667 Torin-2 GSE92742 MCF10A Human 24h 10uM EID0430
Types Number Response transcription factors
Up-regulation 145 TSC22D3; FOXO4; CREG1; ZNF688; HDAC6; ZNF446; KDM5A; HBP1; DDIT3; MNT; PPP1R13L; TLE1; BTG1; TOB1; NR1H3; TGIF1; HTATIP2; SIN3B; CALCOCO1; TCF7L1; ZNF358; ATF4; XBP1; STAT2; KLF11; MXI1; TRIP4; CAMTA2; HMG20B; ELF4; KLF6; MAFF; HSF4; APBB1; ING4; WWC1; IRF7; E2F2; CDX1; JAK2; NCOR2; SP140; TCF15; FOXO1; HDAC5; FOSB; NPAS2; FUBP1; RNF141; ERBB4; PDLIM1; RXRA; SIRT7; PHF1; PBXIP1; CERS4; KLF3; LZTR1; KDM5D; RNF14; MAFG; TSG101; PPARGC1A; MYRF; ZBTB20; ATF3; FLNA; NHLH1; MAFB; EP300; KLF5; CTBP2; ZBTB1; ZIC3; PQBP1; DMTF1; NFE2L1; PRDM4; KLF2; SMAD2; NCOA3; KLF13; NCOA2; SREBF2; MSC; TSC22D4; CIZ1; CEBPD; ZIC1; ERBB2; HINFP; MAF; LIN28A; CSDE1; EZH1; KAT2B; NFATC1; IRF8; EDF1; SOX10; ZNF423; TP63; TRIM29; CITED2; ZNF24; SIRT2; HMBOX1; UBE2B; MTA1; SND1; TSC22D1; NR4A2; POLR3C; ZBTB16; RORA; MEF2C; ZKSCAN1; ZNF532; GTF2IRD1; FOXN3; POU5F1B; LPIN2; ZBED1; TCEA1; FOXD1; ZEB2; ZNF160; SPIB; RCOR3; LMCD1; FOXC1; TGFB1I1; LOXL2; IRF4; TRIM16; PAX5; TCF4; SOX9; KLF4; JUP; CREB3L1; JUND; BASP1; ARNT2; PSMD9
Down-regulation 255 CCNA2; MYBL2; ADRB2; SUV39H1; CDK2; HOXA10; RUVBL2; GTF2A2; ACTL6A; ATF1; CEBPZ; PARP1; RFX5; CBFB; MTF2; ZNF180; TTF2; TFAM; TAF5; IKBKAP; RBM14; RRN3; MED6; CREB5; ZNF134; HES1; RBBP5; ZNF239; ZNF184; SUB1; JUN; HSF2; BRCA1; PSMC3IP; ZNF551; ZSCAN5A; TRIM28; IFI16; ZNF614; TBP; THAP7; SUMO1; YEATS4; PTTG1; ZNF45; ZNF268; REL; ZFX; PBX2; RBBP7; HNRNPD; ZNF468; PLAGL2; DNMT1; BCLAF1; ESR1; ZNF529; TEAD1; CCNC; SNIP1; POLR3F; WT1; NKRF; CCNT1; E2F1; ABT1; ZFP30; RBFOX2; PCBD1; ZNF136; HOXA5; ADNP2; ZNF574; CRY1; TAF4; ADNP; TAF9; TTF1; ZNF493; ZNF329; CENPF; RBL1; CDK8; MGA; TRIM24; MED21; PIAS1; C1D; EZH2; SMARCD2; SCMH1; PEX14; CTCF; TRIM27; MSX1; ISL1; E2F6; USP16; CBX6; WDHD1; ZNF148; ZNF580; CERS6; E2F8; EED; PITX1; ITGB3BP; GABPB1; ZNF586; HEY1; NFKB1; ZNF135; HMGB1; ZNF571; ID1; ELF3; KAT8; NOC2L; NR2F1; TCF20; MYNN; UBP1; TMF1; ETS1; CHAF1B; TAF11; ZSCAN9; ZNF302; IRF2; SMARCA4; NR2F2; GTF2I; CALR; SUZ12; HHEX; MYB; HOXD10; BRIP1; CNOT2; ING2; SIX1; PPRC1; HSBP1; ZBTB38; HLF; NONO; FOXF1; BCOR; ZNF576; FOSL1; LEF1; ZNF107; ZNF443; EHMT2; JARID2; XRCC6; SMAD5; ILF2; ZBTB24; PA2G4; ZNF124; ECD; ERF; HOXA7; MYCBP; ZNF274; HIPK1; MLX; MED20; ZNF22; SMARCD3; ZNF304; C1QBP; BCL10; ZEB1; SMAD1; FOXM1; ZFPM2; THAP1; DEK; HLTF; ASH2L; TLE2; PLAG1; NR1H4; TGFB1; TAF9B; SFPQ; ZNF226; SSX1; WDR77; ZNF227; MEIS2; HOXB2; ZNF222; PIAS2; ID3; NFAT5; BNC2; ZSCAN31; ZNF43; PCGF2; ZNF112; PBX1; WWP1; HIRA; ZFHX3; TRIP6; EYA1; TCF21; SCAI; HDAC2; RFX7; NFIC; SERTAD2; NR4A3; HMGB2; ZMYND11; HOXB7; EHF; TFDP1; FOXA1; NKX3-1; WWTR1; CD3D; EMX2; SLC2A4RG; REPIN1; NKX2-1; MNDA; MECOM; BMI1; SMARCA1; HOXC10; TGIF2; ETV1; MED24; THAP10; ZNF146; ETS2; FOXG1; ZNF652; SNAI2; MEIS1; MYBL1; SMARCA2; SOX17; TCF7; SALL1; AES; MKL2; ELK3; SOX11; ZNF331; RUVBL1
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