Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74665	Torin-1	GSE92742	MCF10A	Human	24h	0.4uM	EID0430

Response Information :

Types	Number	Response transcription factors
Up-regulation	167	PPARD; IRF9; HOXD1; TFAP2A; ZNF217; NRIP1; PBXIP1; ZNF93; OVOL2; ZBED2; CALCOCO1; MEF2D; NFATC4; ZNF350; MED12; FHL2; CERS4; ZNF91; CAMTA2; SUPT3H; ZNF506; PAWR; ZNF274; HDAC9; EP300; BNC1; TGFB1I1; SOX13; TERF1; ZIC1; TCF3; TSC22D3; AFF2; WWP1; ZNF7; MED14; OSR2; ZNF586; ZNF358; PRDM12; PPP1R13L; SIX6; CTNNB1; ZNF85; ZBED1; CDX1; ZNF688; ST18; PRDM10; HIRA; ZFP36L1; ZFPM2; NFE2L2; ZKSCAN1; UBE3A; KLF2; HBP1; NKX3-1; BHLHE41; ZNF141; ZBTB7A; CITED1; ZEB1; HOXB13; BRD4; ZNF611; SRCAP; IRF6; ZNF665; TXNIP; HHEX; SMAD4; TBX3; FOXF2; NCOA2; ZNF721; PIAS1; NR5A2; AR; TRIB3; TLE4; ZNF304; RCOR3; ZNF160; FOXD1; BRCA1; ZNF623; CHD4; FOXO1; BNC2; MAFF; ZNF264; TP63; ZIC3; ZBTB20; SOX2; ZNF43; KDM4C; CBX7; FOXE1; ZNF232; HDAC5; SCMH1; KAT2B; SNAI2; ARID5B; NFIC; BCL10; ZNF273; NFE2L3; TCEA2; NFE2L1; NEUROD1; ZNF83; SALL1; BBX; TSC22D1; ZNF562; ZNF500; GATA6; ZNF12; FOXL2; ZNF329; INSR; EGR2; EYA2; ZFP36L2; IRF7; ARNT; ZNF195; MEOX2; CBFA2T3; GRHL2; TRIM22; RING1; MYCL; GFI1B; JUP; AEBP1; DDIT3; RUNX1; SOX17; SMARCC2; PITX1; ID3; ARNT2; RLF; EGR1; INSM1; ZNF415; EHMT2; CREB3L2; MAF; TCF7L2; HMGA1; ZNF331; ATF3; ESR1; SATB2; TRPS1; ZHX2; NKX2-1; AES; KLF11; KLF9; MSX1; HTATIP2
Down-regulation	176	TCERG1; CCNA2; SUV39H1; CCNH; TP53; RUVBL2; HMGB2; TBP; CBFB; MYBL2; RFX5; EZH2; DR1; CCNC; BRD8; PPARG; MTDH; UBE2L3; AGO2; RBBP8; PMS1; PARP1; TADA2A; NEDD8; VGLL4; MED27; UIMC1; BCLAF1; ORC2; RUVBL1; PATZ1; MNAT1; HOXA5; MAGED1; NELFB; PTTG1; CEBPZ; GTF2A2; PAXBP1; REXO4; PA2G4; ATF1; YWHAB; NUP62; SUMO1; NFKBIB; TAF4B; ZBTB25; HIPK3; ZNF23; THRA; TRIP6; KAT6A; ZNF248; SFPQ; HEY1; SUZ12; CAPN15; ITGB3BP; GTF3A; BRPF1; HOXB7; MTF2; PSPC1; SNIP1; BAZ1A; STAT5B; ELK3; HOXB6; MED1; NR1H3; EED; CENPF; SREBF1; RARB; FOXC1; CRY1; ISL1; KMT5A; ANKRD1; ARID4A; ZNF276; RAN; HOXD10; SAP30; BCL6; ECD; CCDC59; TRIM28; ING2; ING3; HNRNPD; NR2F2; ZNF239; HSBP1; WDR77; PSMD9; HOXC6; SETD3; MEIS1; ENO1; ZNF529; POU3F2; BLM; KDM2A; ZNF22; UBE2I; BANP; HLTF; CENPB; YAF2; HMGN3; YBX1; NFKB1; IKZF5; NAB1; NR0B1; PPARGC1A; RFX7; LHX1; RBPJ; PBX1; HDAC2; NR1D2; ZBTB24; ATF4; PEX2; IRX5; NFAT5; HOXC4; CREM; RNF138; NR2F1; RBBP4; GATA4; MED24; TFDP1; BATF; PCGF2; USP16; MECOM; NFIL3; ETV1; PURA; LPIN2; BCL3; C1QBP; FOXA1; SUB1; NKX2-2; NFIB; SMAD1; ZNF131; RNF141; ZNF516; TAF9B; BCL11B; TBL1X; TOB1; MKL2; NR4A2; ELF5; RBL2; TSC22D2; SIAH2; MYCN; FOSL1; ZNF512B; SOX11; CD3D; ID2; MYCBP; EMX2; BASP1; MEF2C; E2F2