Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74664	Torin-1	GSE92742	MCF10A	Human	24h	2uM	EID0430

Response Information :

Types	Number	Response transcription factors
Up-regulation	129	CEBPA; TSC22D3; CSDE1; MDM4; NRIP1; HMGA2; MNT; MAFF; STAT2; FHL2; FOXO4; EP300; ZFY; DLX4; PHF1; PDLIM1; STAT3; MEOX2; MED12; LOXL2; ZIC1; RBBP5; LITAF; NFATC4; ZSCAN9; PNRC1; CREG1; TGFB1I1; MDFI; BTG1; FOSB; CTNNB1; HDAC4; BPTF; ATF4; THRAP3; ZNF292; FLNA; CDYL; OLIG2; ZNF141; HLX; CDX1; FOXD1; ATF3; SETDB1; MLLT10; TXNIP; ARNT; BARX1; BCL11A; XBP1; ZSCAN18; SOX4; WHSC1; DDIT3; ARHGAP35; SND1; CITED1; ZNF257; BCOR; MYB; FOXF2; ADNP2; PLAG1; IRF1; EGR1; KLF1; NCOR2; YBX3; CNOT1; ZBED2; DDX17; SATB1; ZMIZ2; ZNF117; TLE4; RREB1; RFX7; KLF7; MAFG; RXRA; VPS72; ZNF423; RLF; CERS6; NEUROD1; EGR2; NFKB2; NFAT5; FOXN3; TSG101; ZNF516; EGR3; ZNF274; ETS2; ASCL1; RUNX1; ZFP36L2; TWIST1; TFEC; TBPL1; TOX; NR4A2; JAK2; IRF6; MDM2; IRF7; ZSCAN31; SMARCD3; HTATIP2; KDM5D; EN1; HMGB3; ID4; TRPS1; ZEB2; MYCN; SMAD2; TBX3; NKX2-1; TRIM16; ARNT2; BASP1; BHLHE41; MAF; MAFB; SOX9; HDAC2
Down-regulation	202	NFKBIA; MYBL2; SUV39H1; CCNA2; ZNF148; HOXA10; RFX5; THAP7; TRIM32; ORC2; ADRB2; RBM14; TAF5; PA2G4; ELF3; YWHAB; HMGB1; ZNF672; GTF2A2; ZSCAN5A; MTDH; SP3; UBE2L3; ELF5; EZH2; RUVBL2; BRCA1; E2F1; MEN1; TRIM28; DNAJC1; NFKB1; SMAD7; MYNN; MTF2; DDX54; ZNF384; NR2F2; MXD3; MED6; SIM2; TAF4; ZNF136; REXO4; ATF1; AGO2; TCF20; ZNF430; RERE; SSX1; TTF1; NELFB; ZNF652; PSPC1; NKX3-1; ACTL6A; ESRRA; MKL1; ZFP36L1; SFMBT1; ST18; TFAM; CCNE1; HMGB2; UBP1; GATAD2A; MEIS2; PPRC1; PSMC3IP; COPS5; HMGXB4; NR1H4; WWTR1; ITGB3BP; TRAK1; NOC2L; TMF1; ZNF468; EED; IRF2; ZNF32; PATZ1; TGS1; FOXM1; ID3; MED21; IKZF5; HOXC6; BRD7; ZNF22; SUZ12; ZNF44; CBX6; BLM; BRD8; SMARCD2; ZNF24; MED27; VEZF1; SSRP1; RAN; HOXC10; TAF1C; ZNF264; HOXB7; BAZ1B; E2F6; ZNF239; FOXJ1; YEATS4; CREB1; CCDC59; RBL1; ATF7IP; MXI1; CARM1; SMARCD1; ID1; KLF2; HCFC1; STAT1; MYT1L; MED1; TSC22D2; PSMD9; CBFB; KDM2A; ZNF266; REL; ELK3; HOXA1; MLXIP; CRYM; TBL1X; BAZ1A; PHF8; SMARCA4; RBBP7; ADNP; E2F8; FOXC1; BMI1; RBPJ; PCGF2; ZNF467; MED4; RYBP; WWC1; PFDN5; CREBZF; GTF3A; HIRA; DEAF1; NCOA4; ZNF232; C1QBP; HNRNPD; SMARCC2; SMAD1; TEAD4; ATN1; PSMC3; EMX2; PITX1; TGFB1; RBPMS; RORA; MYCBP; HOXB2; NPM1; STAT4; SIX2; PURA; CRY1; ZHX2; PSIP1; PBX1; TRIP6; ETV1; AIP; TSC22D1; YAP1; NFIB; FOXG1; ZNF91; YBX1; CBX3; ZNF107; HLTF; BCL11B; FOXA1; IFI16; TCF4; MKL2; MEIS1; MECOM; MEF2C; SHOX2; GATA2; ZBTB18; ID2; E2F2