Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74649	Fostamatinib	GSE92742	MCF10A	Human	24h	0.4uM	EID0430

Response Information :

Types	Number	Response transcription factors
Up-regulation	206	NR3C1; SSBP2; HOXD1; ERBB4; PAX8; ZIC1; HOXD3; WT1; CREBL2; MEIS2; IRF9; NFE2L2; CREM; SUPT3H; HDAC5; FOS; NFKB2; STAT2; SIM1; VGLL1; TCF7L1; NR4A2; BRWD1; PBX2; ZZZ3; DAXX; ZNF217; RARG; MYCL; NFYC; OVOL2; ZNF512B; FOSL2; CBX7; PRDM2; TFAP2A; MZF1; ZKSCAN4; ZNF331; KDM4A; THAP7; NR1H4; ZNF586; NCOA2; ELF2; ZNF136; YEATS2; ELF3; NFYA; HDAC9; RSF1; CDK2; ZNF253; ZNF467; RORC; LIMD1; PHF1; PRMT2; TERF1; HIVEP1; FOXI1; ZNF304; ZBED2; TAF5L; ZNF551; ZNF268; AR; ZNF682; BCL11A; CREB3L2; TCF25; RRN3; BNC2; IRF7; BHLHE41; CREB5; SOX13; GTF2I; ZFP69B; TAF11; ATF2; MAML1; PNRC1; ARID5B; CSDC2; SCMH1; KLF4; USP16; FOXN3; ZNF93; CALCOCO1; ZEB1; ZNF665; ZNF623; CARHSP1; MXD4; ARNT; REL; SCAI; SSBP3; IRF2; SETDB1; TFAP2C; SMAD6; ZNF345; ZNF329; E2F8; PHF20; URI1; MED21; MED6; ZNF239; POLR3C; ID4; SSX1; CERS4; INSM1; ZNF43; TRIM24; MECOM; ZNF394; FOXF2; ZNF263; SMARCA1; CDC5L; PFDN5; GATA6; TRPS1; SP3; ZNF264; SP100; TSC22D1; HBP1; RING1; BCL6; TEAD4; IFI16; TGFB1I1; ZNF423; ETV5; DBP; ENO1; BACH1; ZNF33B; EMX2; KLF2; ZXDC; ELF4; BRIP1; CLOCK; MEF2A; TRIB3; ZNF611; TEAD3; NFKB1; FOXG1; TCF4; AHR; DEK; ZHX2; LITAF; ZNF273; TP63; STAT4; DEAF1; MEF2C; SP140L; ZNF12; GTF2F1; REPIN1; PRPF6; SIX2; NPAS2; ZFPM2; ATF7IP; KAT2B; ARNT2; TBX3; HLF; KLF11; SALL1; BHLHE40; TRIM29; EYA2; TCEA2; SOX10; ST18; BCL3; THAP10; AES; RORA; HMGA1; MNDA; MEIS1; TFDP2; JUNB; HOXB2; INSR; SOX17; NAB1; BRD2; JAK2; NEUROD1; ZFP36L2; MKL2; ESR1
Down-regulation	205	PCBD1; PARP1; ATF6; PPARG; ADRB2; RUVBL2; CBFB; SMARCA4; SMARCE1; NRIP1; ELF1; PSMC3IP; MTDH; PMF1; UIMC1; MTA2; MLX; GMNN; AATF; MYBL2; ATF5; HMGB3; TCERG1; CARM1; HOXB9; CDX2; MAGED1; TBP; HAND1; TLE1; TBX10; VEZF1; CALR; TEAD1; ZMYM2; ZNF576; E2F3; ASCL1; HOXB7; VGLL4; BRCA1; ID3; YWHAB; NOC2L; BAZ1A; RBBP7; SUV39H1; VSX1; HOXB6; KDM2A; TLE4; SAP30; PRKDC; ZNF587; CHD7; ETS1; PIR; DRAP1; HOXA1; ZBTB18; KAT6A; SOX15; MED1; PREB; GABPB1; KLF7; MYB; YAF2; TSC22D4; CEBPD; HOXA11; NUP62; WHSC1; RUVBL1; NRBF2; FLNA; MTA1; RBM14; SMAD5; ZNF23; BTG1; BRF2; POU3F2; FOXO1; SUZ12; PIAS2; MDFI; HSF2; CDX1; NR1I2; ZBTB7A; CCNT1; GMEB1; EZH2; ZNF226; HDAC1; BCL11B; POU2F2; CBX3; SUB1; TRRAP; TCF20; RNF6; DDIT3; COPS5; PPARGC1A; MLXIP; AFF4; RNF138; UBE2I; SSRP1; NKX3-2; ZNF222; MSX1; ZNF443; HMGB1; ZFP36L1; PAX5; STAT3; FOXA2; HOXB5; CDK8; HR; PTRF; CCDC59; POU2F1; LEF1; BAZ2A; SOHLH2; JARID2; EGR2; TBPL1; SMARCC1; SOX4; ISL1; BRD8; ZNF32; NCOA6; NFIX; HOXD10; TRIM16; VDR; ZNF562; LOXL2; WDR77; TAL1; ZNF143; ZNF432; HMBOX1; BMI1; FOXA1; BASP1; ZNF267; PA2G4; BTAF1; CTR9; EGR3; RB1; ZBTB43; TWIST1; ZBTB20; HOXB13; SMAD3; CCNC; NKX2-2; TERF2; RNF141; HSBP1; ANKRD1; ZNF552; TAF10; TOX; ARID1A; BRD3; EED; ZNF516; CEBPG; ZBTB38; RUNX3; MITF; NFAT5; NPM1; ING2; PCGF2; POU2AF1; GATA4; TSC22D2; BATF3; TRIM22; C1QBP; TAF1D; HTATIP2; PURA; HDAC2; SNAI2; POU4F1; SMAD1; HHEX; MAFB; NFATC3; ETV1; ZNF281; HOXC6; RELB; E2F2