Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74648	Fostamatinib	GSE92742	MCF10A	Human	24h	2uM	EID0430

Response Information :

Types	Number	Response transcription factors
Up-regulation	75	NFKBIB; MYBL2; MAX; ZNF586; SNAI1; TFAP2C; WNT4; ZNF212; IRX5; FOSB; ZNF3; SMARCE1; AEBP1; DNAJC1; DAXX; CARHSP1; DBP; EPAS1; ING1; NFATC1; YWHAB; RARA; RUNX1; CREBZF; GTF2I; BHLHE40; NFIC; SATB2; VDR; NFKB1; STAT3; SMARCB1; TOB1; NFYC; TSC22D3; ZBED1; NR4A3; EDF1; ID4; RREB1; PITX1; MSC; HDAC4; KLF5; KLF9; OSR2; HDAC1; TGIF2; KLF4; TBL1X; RBPJ; AES; NR2F1; SIX3; SMAD3; ATF3; LEF1; HSBP1; EYA2; HES1; KLF6; TRIM29; REPIN1; POU4F1; JUND; FOXO1; ESR1; ZBTB16; SIAH2; BRD2; KDM5D; PEG3; DACH1; PSMD9; HDAC2
Down-regulation	61	ACTL6A; HOXB7; TFEC; HOXB5; ASCL1; HOXB6; ZNF217; CREB5; APEX1; KAT2A; BLM; SSX1; NR1H4; ANKRD1; DLX5; RCOR1; SUZ12; XRCC6; PEX14; HMGB2; ZNF721; RUNX3; SIM2; CIC; NR5A2; DLX2; THAP10; YBX3; DDIT3; ERBB4; MNDA; ELK3; ZNF195; DEK; ZBTB20; ZNF117; ARNT2; HDAC9; SOX17; SUB1; ZNF267; YEATS4; FOXF2; TCF7L2; MSX1; ZSCAN31; CTBP2; RNF6; ILF2; EHMT2; IRF4; FOSL2; ZNF160; SMARCA1; TRIM22; MYCN; MECOM; ZNF652; C1QBP; HOXB2; MYBL1