Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74647	Fostamatinib	GSE92742	MCF10A	Human	24h	10uM	EID0430

Response Information :

Types	Number	Response transcription factors
Up-regulation	76	TXNIP; CREBL2; TSC22D3; VEZF1; DNAJC1; NCOR2; NEDD8; MITF; ZMIZ1; TCF12; MECP2; FLNA; HIVEP1; AHR; GATA6; RBFOX2; ARNT; LIMD1; CNBP; HIPK1; NRBF2; MNT; ISL1; PAX6; PKNOX1; TLE4; MEIS1; ZNF32; IRF5; INSM1; EHF; FOSB; ZFHX4; REST; ZSCAN9; RB1; TWIST1; SOX4; BCL3; EED; ERBB4; SMARCA2; NAB1; ATF3; STAT3; ELF4; BMI1; EGR1; EGR2; SIAH2; ELK3; SMARCD3; ZEB1; EGR3; TOX3; KAT2B; VPS72; MLXIP; SNAI2; TGFB1; LMCD1; ETS2; CUX1; ESR1; NEUROD1; NR4A1; IFI16; NFIB; MEIS2; AEBP1; KLF4; TRPS1; ARNT2; TBX3; ZEB2; PSMD9
Down-regulation	66	NR2F6; SUV39H1; ADRB2; ORC2; TAL1; TCF20; PITX2; HMGB2; DRAP1; TAF5; HOXC10; ETV4; NOC2L; PMS1; SSX1; HMGB1; PSPC1; CBX6; RUVBL2; ELF5; SOHLH2; PHIP; ZNF721; SOX9; CIITA; FOXE1; PA2G4; ZNF544; SUZ12; TRIM28; TRRAP; IRX5; CTR9; ZNF224; MYT1L; HIRA; APEX1; GATA1; GTF2IRD1; CARM1; NKX3-1; PQBP1; CENPF; PRRX2; HHEX; CTBP2; HOXC6; EN1; MED1; SCAND1; ZNF160; ARNTL2; TSC22D1; NKX2-2; WT1; CITED2; SATB2; POU2AF1; ZBTB16; PAX5; HMGN3; ZBTB18; MYBL1; ID1; ID2; E2F2