Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74628	Pf-562271	GSE92742	MCF10A	Human	24h	2uM	EID0430

Response Information :

Types	Number	Response transcription factors
Up-regulation	132	CREM; NFE2L2; AR; MECP2; ARID5B; IRF9; ZNF711; RELA; SETDB1; BNC2; SPDEF; INSM1; PIAS1; PHIP; ZFPM2; SOX11; PAX8; EP300; NFATC4; MAML1; ACTL6A; URI1; NFYC; CBX7; HMGXB4; NR1H2; EYA1; HIVEP1; PRDM2; IRF6; TGFB1I1; ELF3; FOXN3; SMARCA1; RERE; NFKB2; PATZ1; ZNF512B; ZNF467; MEIS2; NR4A2; DAXX; TXNIP; ZNF586; CLOCK; RBFOX2; SCMH1; KLF11; ZNF329; TAF11; CHD3; SREBF2; ZNF239; LZTS1; RBM14; ACTL6B; FOSB; MYT1; TEAD3; NR2C1; MNDA; ZXDC; JUN; EMX2; ERBB4; HDAC4; TLE2; NCOA6; IFI16; AES; RING1; TCF4; YWHAB; TFDP2; IRF7; ZNF551; SOX13; ZEB1; TCF25; SSBP3; TRIB3; HIPK1; EHMT2; SALL1; NEUROD1; SERTAD2; ETV5; HOXB2; ARNT; CREB3L2; INSR; ESR1; SIX3; GTF2F1; WNT4; ZFHX3; HLF; TCEA2; BCL3; SF1; SOX17; MYCL; REPIN1; ZBTB20; ARNT2; ZNF410; CAMTA1; STAT4; NR4A1; FOXE1; TRIM16; WT1; TBL1X; HMGN3; RUNX3; SIAH2; EHF; PCGF1; ZNF423; YAP1; ETS2; NFE2L3; BACH2; MEIS1; KDM5D; TFAP2C; EGR2; SHOX2; ID2; FOXG1; DACH1; HDAC2
Down-regulation	138	CCNH; ATF1; ASH2L; TP53; BLZF1; ZNF432; NRIP1; TCERG1; ZNF426; ETS1; STAT5B; ZNF721; GABPB1; ELF1; STAT3; TMF1; CDX2; CDX1; AATF; NR2E1; RUNX1; PDLIM1; TEAD1; NR1H3; SOX15; SPIB; IKZF5; BRD8; NR2F2; ARNTL; RNF4; PSPC1; ZNF224; YAF2; TGFB1; ZNF222; ZNF205; DDIT3; CALR; HEY1; NRBF2; SUZ12; NFE2; SOX4; BATF; KLF5; SMARCB1; EGR4; KAT2A; MED7; BAZ1A; POU3F1; BHLHE40; TAF1A; TCEA1; HOXA1; ZNF274; CTR9; LOXL2; DLX2; ADNP; BLM; MED1; CTBP2; KMT5A; ELK1; ZNF177; SP140; MAGED1; NR1I2; BMI1; LPIN2; ZNF557; BRCA1; TOX; TSC22D4; HOXC6; ZNF302; E2F3; PTRF; GATA4; LITAF; ZNF430; PA2G4; CEBPD; TAF10; ELF5; RBBP7; ZNF552; ZNF143; ZNF91; ASCL1; TULP3; PHF8; SIRT2; EGR3; TAL1; ZNF195; TOX3; RYBP; RB1; FOXF1; ZEB2; LYL1; ANKRD1; ZNF226; ZNF165; CENPF; NPAT; NFAT5; RBM39; GFI1; HOXB6; FOXO1; MYCN; ZNF266; FOXC1; SOX10; PURA; SMAD3; MAFB; ZBTB18; MYRF; ID3; SNAI2; ZNF146; KLF6; FOSL1; EGR1; TWIST1; ERG; HSBP1; PAX5; HTATIP2; BHLHE41; PEG3; E2F2; RELB