Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74618	Palbociclib	GSE92742	MCF10A	Human	24h	0.08uM	EID0430

Response Information :

Types	Number	Response transcription factors
Up-regulation	97	PPARG; HLX; IRF9; SPDEF; HLF; MEIS2; HOXD3; IRF1; PRDM14; CSDC2; NFE2L2; RELA; ZNF544; ZNF117; PCGF2; SOX13; EYA1; TSHZ2; TGFB1I1; TFAP2C; HIPK2; ZNF467; CUX2; SIRT7; NR2F1; ZNF239; DAXX; AR; FOXK2; PHIP; PKNOX2; RBPMS; ZNF623; SMARCA1; FOXI1; ZSCAN9; ZNF512B; RING1; TEAD3; THAP10; ZBED2; MEF2C; NFKB1; DACH1; TFCP2; FOXA1; CITED1; PITX1; SNAI2; BNC2; ZNF264; PCGF3; SMARCD3; SOX11; TCF4; ZFPM2; HOXB2; PIR; MNDA; CTBP2; GTF2IRD1; RBPJ; FLI1; CRYM; RSF1; YAP1; EHF; NR4A2; RREB1; RYBP; ZBTB20; ESR1; SMARCA2; TRIM29; EHMT2; NFKB2; KDM5D; CREB3L2; REPIN1; IRF6; ELK3; ARNT2; BCL3; FOXG1; ETS2; PEG3; TBX3; HMGA1; MYCN; SIAH2; SALL1; ZNF423; TRPS1; ZNF331; EN1; LEF1; HDAC2
Down-regulation	130	ATF1; FUBP1; TP53; BMI1; THAP7; KDM5C; HOXA1; YY1; GABPA; MAGED1; NRBF2; UBE2L3; CRY1; JARID2; SP140; ZNF14; TOB1; RFXAP; NCOR2; URI1; SMARCB1; PA2G4; IRX5; MTDH; PATZ1; TOX; PDLIM1; MXD4; MYNN; PMS1; YAF2; BTG1; BANP; SERTAD2; SAP30; STAT6; ID3; SAFB2; PRKDC; TDRD3; CALR; RNF14; HSF2; KAT6B; CBX6; BBX; NR1I2; ZNF177; TFDP2; ZNF302; ELF1; TCF12; SMAD7; PURA; DLX2; ZNF226; PAX6; IKZF5; MED7; BCL11B; BATF3; TOPORS; GCFC2; BRCA1; ZNF222; PSMD9; ZNF432; REL; ING2; RUNX3; CCNE1; WHSC1; TXNIP; TSC22D4; PSMC3IP; CITED2; HLTF; THAP1; TEAD1; TTF1; EGR1; FLNA; MED1; NFIC; VDR; PEX2; LHX1; CARM1; TBPL1; TSC22D2; SMAD1; HDAC9; STAT3; ST18; PSIP1; SOX4; HTATIP2; FOXC1; ZNF430; PAX5; ZIC1; TCEA1; ZNF529; SMAD3; NKX2-2; YEATS4; FOXD1; HOXC6; NAB1; ZNF281; LPIN2; EGR2; SAP18; TCEA2; NFIL3; BRD4; ASCL1; C1QBP; SPIB; BACH1; MEOX1; NR0B1; MKL2; ETV1; KLF6; ZNF91; MSX1; ID2; E2F2; RELB