Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74617	Palbociclib	GSE92742	MCF10A	Human	24h	0.4uM	EID0430

Response Information :

Types	Number	Response transcription factors
Up-regulation	181	PPARG; TBX2; STAT3; SMAD6; ZNF248; HLX; PIAS3; ZNF711; MZF1; DLX5; SETDB1; ZKSCAN4; ZXDC; AR; ZNF623; HIPK1; ZNF75D; MAK; PAWR; USP21; HIVEP1; NFE2L2; ZNF446; ETS2; BARX1; SSBP2; AFF2; MEIS2; ZNF444; OVOL2; ARNT; TXNIP; JUN; RREB1; RNF2; ZSCAN9; NFKB2; BCL6; ZNF219; CREBL2; BCL11A; ZIC1; ARID5B; DAXX; MNDA; ZNF606; MECOM; CREM; SUPT3H; ZNF835; GATA2; DLX4; NKX2-1; ZSCAN31; ZNF16; ZNF551; ZNF180; ZEB1; ZNF423; FOSB; HINFP; ISL1; CREB3; SMARCA1; PAX8; ESR1; FOXF2; RBFOX2; HOXC13; ZNF350; MECP2; NFE2L3; TRIB3; ZFHX3; E4F1; ZNF629; ARHGAP35; ID4; EHMT2; PHOX2B; NR2F1; ZNF263; ZNF586; ATF3; ZFPM2; CLOCK; SOX17; PNRC1; NFATC1; CUX1; IRF1; ELK4; AHR; HMGXB3; FOXI1; TRIM24; BACH1; TGFB1I1; ERBB4; PLAG1; TADA3; CAMTA1; WT1; PIR; ZNF329; SCMH1; PFDN5; BCL3; GRHL2; ZNF500; FOXF1; KLF3; NFX1; SOX5; ZBED1; TFAP2C; ZNF12; ZNF512B; ZNF175; BCOR; MEIS1; HDGF; SUPT4H1; ZNF304; SATB1; AES; WWP1; TLE2; REPIN1; BRCA1; ZNF112; ZNF467; NR4A1; HDAC4; PIAS4; PAX6; TRIM16; MBD2; MDM2; YEATS2; ZSCAN16; TRIM27; TRPS1; ZNF239; THAP10; ITGB3BP; ARNT2; TCEA2; SOX11; SMARCC2; ID1; SMARCD3; CITED2; CHD9; TCEB2; PRMT2; HLF; GTF2F1; DACH1; KLF4; TBX3; ZNF281; IRF6; BNC2; FOXN3; ZNF331; TDP2; TRIM29; NEUROD1; MYBL1; EN1; EYA2; ENO1; BASP1; MAF; BHLHE41; ZBTB20; KLF6; EMX2; LEF1; POU2AF1
Down-regulation	200	RHOA; MAGED1; TLE1; TFAM; TP53; CCNA2; BRD8; SUV39H1; PDLIM1; KDM5C; TMF1; FHL2; ATF1; VGLL4; TADA2A; CTR9; MTDH; CCNC; CREB5; PHF8; TCERG1; ST18; SOX15; PMS1; TBP; ZHX3; PAXBP1; SMAD5; ZNF23; ETS1; HOXA1; HLTF; ZBTB25; ORC2; ARNTL; SMAD7; BBX; ATF5; ESRRA; HOXA5; KAT6B; IRX4; GATAD2A; ADRB2; TERF2; CHD1; GABPA; TAF10; KDM2A; AATF; NR2E1; GABPB1; MED1; ARID4A; HMGB1; ASH2L; ING3; POLR2A; SMAD1; BMI1; DNAJC1; CBFB; ZBTB7A; KAT2A; BATF3; MXI1; HOXC6; NFIB; HOXA10; BAZ1B; NRIP1; ING1; SUZ12; HMGB2; NUP62; IKZF5; NR2F2; HTATIP2; CEBPG; AGO2; TFEB; ID3; ZNF226; ETV6; HOXB7; RBM14; TSC22D4; PROX1; YAF2; USP16; BLM; NFE2; MLX; C1QBP; TRIP6; POU3F2; SPEN; SREBF1; TEAD1; SIM2; SMARCA5; SPIB; ELK3; CCNT1; AFF4; MXD1; RBBP7; BAZ1A; JARID2; ZBTB24; CITED1; TSG101; TRRAP; INSM1; IRF7; CARM1; KMT2B; EGR1; NR1H4; HIPK3; DDIT3; MLXIPL; HOXA7; TTF1; HDAC9; PRRX2; ZNF146; WWTR1; BTG1; ZNF222; PA2G4; SMARCC1; NFAT5; HMBOX1; PRKDC; APEX1; KDM5D; ATF7IP; ADNP; MED24; RNF138; ZNF124; TBPL1; FOXJ3; KLF2; MYT1L; MLXIP; HSF2; RB1; BRD3; ASCL1; SMARCA2; IRF8; PHF20; ZNF430; AIP; FOXC1; IFI16; SMAD3; CRY1; DPF2; ERG; TCEA1; PLAGL1; UBE2B; BCL11B; IRF2; MYRF; CTBP2; EGR3; AFF1; ZNF22; BRD4; RNF141; HMGN3; SOX10; ZNF266; CREB3L1; RBL2; FOXD1; ELF5; HDAC2; AEBP1; ETV1; NAB1; PAX5; HMGB3; TGFB1; SUB1; ZBTB18; ZEB2; RBPMS; PBX1; SOX9; JUND; GATA3; MEF2C; PBX3; E2F2; RELB