Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74616	Palbociclib	GSE92742	MCF10A	Human	24h	2uM	EID0430

Response Information :

Types	Number	Response transcription factors
Up-regulation	57	ZMYM2; ZNF217; PAX6; FLI1; EGR1; ZNF544; TRIP6; PBXIP1; TOX3; KLF2; MEF2C; RXRA; ZBED2; TRIM27; CRYM; LOXL2; CTBP2; CERS4; CUX1; WT1; TULP4; SOX4; ZSCAN31; TOPORS; MLXIP; ZNF117; RUNX1; BCL11A; ZNF274; IRF1; JAK2; MYRF; ZNF91; KLF11; BACH2; IRF4; HMGB3; MNDA; IRF6; ERBB4; TFAP2C; SNAI2; JUP; KLF10; ZNF532; KLF6; POU2AF1; TCEA2; PAX5; BASP1; ARNT2; DACH1; SOX9; MYBL1; HIF1A; PSMD9; HDAC2
Down-regulation	63	CCNA2; MTDH; ASH2L; KAT7; HOXC11; TOB1; RBBP7; LPIN2; TULP3; HOXB13; SUZ12; BRCA1; TERF1; RBM14; DNMT3B; ZEB1; EZH2; SMARCC2; YWHAB; ISL1; ZBTB16; FOXM1; PRRX1; ZFHX3; PA2G4; BCL11B; CARHSP1; HIPK1; SLC2A4RG; CALR; SMAD1; MSX1; TBL1X; MAFB; RBBP8; TEAD4; HOXC6; HIRA; HLTF; HOXB7; ING2; HOXC10; ELF5; FOXF1; NR2F2; BRD4; KDM5D; TCF7; LEF1; AEBP1; MEIS1; JUND; NFIB; KAT2B; IFI16; CD3D; ID4; KLF9; TWIST1; SMARCA1; RBPMS; ID2; E2F2