Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74613	Osi-027	GSE92742	MCF10A	Human	24h	0.4uM	EID0430

Response Information :

Types	Number	Response transcription factors
Up-regulation	215	STAT2; AR; HOXD1; STAT3; ZNF711; NFE2L2; ZNF350; ZNF248; ZNF93; TGFB1I1; TADA3; FUBP1; ZIC3; AFF2; HOXB13; ARID5B; IRF9; NFKB2; RSF1; PRDM1; LIMD1; MDM4; UBTF; ZBED4; SPDEF; TCF4; POU2F3; YEATS2; TAF1A; ZNF512B; DLX4; REL; CREM; ETV6; ZNF7; TFAP2A; TBL1XR1; TXNIP; TCF7L1; EP300; EHMT1; ZNF124; DAXX; TAF5L; HOXA3; PML; ZZZ3; NLK; ZFPM2; OVOL2; ZNF345; HIRA; SUPT6H; CDK2; E4F1; ZNF141; BRWD1; ZNF117; POU2F1; SOX12; ZNF682; L3MBTL1; HESX1; ZNF768; ESR1; ZNF273; KLF3; ARID5A; CARHSP1; ID4; SCAI; SOX5; NFE2L3; ZNF215; ZNF444; ZNF3; SIM1; DLX5; PRDM12; BCL6; CITED2; RARG; ZBED2; BCL11A; USP21; ZNF12; ZNF134; SMAD4; NUP62; ZNF250; MNT; CSDC2; TEAD3; NFE2L1; RREB1; MED12; CALCOCO1; ZNF551; ELK4; ZNF586; PAWR; TBX3; E2F2; ZNF419; SPI1; SREBF2; ZNF43; NFATC4; SMARCA1; CREBZF; PRMT2; NAB2; CBFA2T3; NCOR1; FOXF2; ARL2BP; CDIP1; IRF6; ZNF423; ETV5; ZNF623; CIZ1; ZNF500; ZNF606; ARID1A; TEAD4; LIN28A; TRIP4; FOXJ2; RBBP8; ZNF74; ARNT; GTF2F1; THRAP3; KLF4; ZNF611; CDK9; CBX4; ZNF667; HIVEP1; KLF13; ERBB4; EDF1; NHLH2; ZNF160; MYB; SOX11; TRPS1; BRF2; TRIB3; SIAH2; RNF14; CTNNB1; IRF8; TCEA2; ZNF629; GTF2I; ZXDC; JUN; HEY2; OSR2; CLOCK; NR2F1; ZBTB16; ZFP69B; KLF11; KLF1; ZNF331; PHF20; SERTAD2; ARNTL2; HHEX; PRRX2; ZFHX3; FOXN3; ARNT2; CNOT2; SALL1; CBX7; MYRF; JAK2; MEF2C; WNT4; NEUROD1; AES; RCOR3; GFI1B; HLF; NR4A2; ZNF22; SATB2; BHLHE41; SIX3; SHOX2; PRRX1; MDM2; SMARCC2; SOX17; NKX3-1; CERS6; TFAP2C; IRF7; SMAD2; TLE2; WT1; SOX9; PEG3; EN1; MAF; ZNF91; JUND; DACH1; TRIM29; HOXB2; MAFB
Down-regulation	269	CCNA2; ATF1; SUV39H1; TLE1; ATF6; CBFB; TP53; TCERG1; PPARG; HEY1; RUVBL2; ELF1; TBP; BRD8; BMI1; TMF1; YAF2; UIMC1; ADRB2; TAF5; MYBL2; ID3; TTF2; HOXA5; MED1; PMS1; SSRP1; EP400; RBBP7; ARNTL; AATF; DDIT3; ZNF32; ASCL1; GABPB1; ZNF302; ZNF23; UBE2L3; MED6; PTTG1; SMARCA2; BRCA1; HOXB7; PSPC1; PDLIM1; EZH2; CCDC59; GMEB2; ZNF576; PURA; COPS5; ELK1; SOX15; USP22; MED27; TFAM; CREB5; SMARCE1; MED31; MTDH; MNX1; GTF2A2; EED; ZNF177; NCOA4; C1D; ORC2; NCOA6; ING3; TCFL5; SUB1; ELK3; KMT2B; NRBF2; TSC22D4; MTF2; PHF8; ZHX3; HOXA1; SIX1; NFIL3; TGFB1; KAT2A; E2F3; TAF4; BAZ1A; RUVBL1; TEAD1; ZNF222; KAT6B; HLTF; SUPT7L; NFKBIB; ECD; BCL11B; CTR9; CXXC1; BRD7; ZSCAN5A; NRF1; ZNF384; ATF5; HSBP1; HOXA7; MLX; ZBTB40; BTG1; KLF2; CIC; FOXA2; MED7; FOXD1; CEBPZ; ZNF552; ZNF45; IKZF5; WDR77; DNAJC1; NOC2L; TAF9; ITGB3BP; CENPB; SNAI2; SOX4; XBP1; XRCC6; FOXJ3; CDX2; POLR2A; BAZ1B; BANP; RYBP; BLM; SNW1; ERF; NR2F2; KLF12; NR1I2; SIM2; TFAP4; PIAS1; PSMC3IP; CENPF; ZBTB11; CBX3; POLR3F; SAFB; RNF6; TOPORS; ZNF574; PEX2; NEDD8; ZNF226; ZNF200; ZNF148; TCF20; SUZ12; POU2AF1; TFEB; SMAD7; JARID2; CALR; ZNF143; HMGB2; HR; DDX54; TRIP6; PIAS4; SMAD1; PEX14; HMGB3; CCNC; ZNF573; TAF10; CNBP; USP16; MED21; MLXIP; TCF25; MSX1; POU3F2; ZNF266; NR1D2; RUNX1; AFF4; BBX; PSIP1; ZNF432; BATF; HSF2; BAZ2A; NR1H3; MED24; KLF7; CRY1; ZNF24; TCF21; PRKDC; ABT1; CNOT1; ZMYND11; TCF7; BTAF1; NCOA3; TFDP1; HOXC4; ZBTB38; TCF12; BRD3; SAP18; RB1; TULP3; TRIM27; ZNF282; SREBF1; SALL2; TSC22D1; SMARCD2; CRYM; CARM1; ZNF267; LITAF; KMT2A; PAX5; CTBP1; ADNP; ID1; PSMD9; NFIB; PLAG1; AIP; TSG101; ETV1; INSR; EGR3; HMGB1; GLI3; SMARCD3; LPIN2; TBPL1; FOXF1; SCAND1; BATF3; LEF1; HOXC6; RBM39; ZNF516; BASP1; C1QBP; HDAC2; EGR1; NFAT5; ZSCAN31; EGR2; FOXO1; GATA3; CD3D; KLF5; KLF9; LYL1; PBX1; TOB1; CHD7; FOXC1; HTATIP2; GATA2; RELB; MYCBP; ID2