Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74611	Osi-027	GSE92742	MCF10A	Human	24h	10uM	EID0430

Response Information :

Types	Number	Response transcription factors
Up-regulation	127	HDAC6; FHL2; MAGED1; TSC22D3; FLNA; NRIP1; RNF14; IRF9; CALCOCO1; CDK7; SMARCC1; ZNF446; NR1H3; ZMYM2; ZNF264; FOXO3; FOXO4; CREG1; MED15; LMCD1; BCL10; ZSCAN18; PHF1; MYB; ZKSCAN1; HMGA2; TAF7; ZNF506; ZNF688; PBXIP1; TGFB1I1; PDLIM1; ASCL1; EGR1; EP300; MAFF; AFF1; SALL2; KDM4C; APBB1; ZMIZ2; TCEB2; MAF; ZBTB20; TCF7L1; HDAC9; RXRB; ZNF768; ELF3; ZBTB1; ERBB2; GATA6; CARHSP1; TP63; CITED2; MYRF; PPARGC1A; CRYM; ZNF587; PTRF; RERE; ELF4; TERF1; PPP1R13L; MAFB; ELF1; BRF2; HLF; SNAI2; OLIG2; TFEC; ZNF606; DPF2; SUPT3H; LOXL2; RCOR3; TXNIP; FOSB; RBPMS; KDM5D; TSG101; SND1; ZNF267; IRF5; ZBTB38; FOXN3; CTBP2; HTATIP2; ZNF274; MXI1; NANOG; NFE2L1; ZNF665; KAT7; TFDP2; COPS2; FOXD1; ZNF423; MTA1; BASP1; POU5F1B; CREB3L1; JAK2; ETS2; EGR3; CHD7; ZNF532; SOX9; ZBTB16; RUNX1; MITF; ZNF160; SCAND1; KLF6; KLF11; TDP2; TBX3; SALL1; AEBP1; INSR; SMAD3; TRIM22; ID2; ID4; SMARCA1; EYA2; DRAP1
Down-regulation	131	ATF6; NR2F6; MYBL2; SUV39H1; CCNA2; TFAP2A; THAP7; MTDH; ADRB2; RBM14; RAN; EZH2; AGO2; PARP1; RFX5; HEY1; GTF2A2; MBD3; PA2G4; NOCT; WHSC1; MTF2; PSMC3IP; FOXM1; TAF1A; CCDC59; MYC; PMS1; LZTS1; CCNC; PRDM1; PITX1; CENPF; SUMO1; NFKB1; ZNF24; ZNF571; KMT5A; BRCA1; CCNE1; RARG; TBP; RAD21; BAZ1B; ZBTB40; DNMT1; PITX2; CREM; SOX18; CALR; SSRP1; PURA; TLE4; SOX10; CNOT3; TTF1; PHIP; RBL1; ATF4; RBPJ; ESRRG; BLM; CERS6; WDHD1; CCNT1; MED21; BAZ1A; ZNF32; ELF5; RFC1; NR1D2; TAF5; TFDP1; REL; SUZ12; FOXC1; FOXF2; EED; VDR; HSF2; BCLAF1; ZNF140; PSMD9; C1QBP; SLC2A4RG; IRX4; TAF11; HDAC1; PLAGL1; SKIL; SMARCA5; MEOX2; TEAD4; ZFHX4; APEX1; SMAD6; ZNF529; ILF2; ZNF124; ISL1; RBBP8; MSX1; CRY1; TBL1XR1; BRD7; NPM1; EMX2; HDAC2; HES1; TGIF2; ZNF512B; EPAS1; RUNX3; YEATS4; SUPT4H1; ZNF107; HLTF; MYCBP; BATF3; TGFB1; NAB1; ZHX2; MED24; DACH1; ZNF146; NFIB; MYBL1; MECOM; NFATC3; E2F2; MEF2C