Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74601	Mk-2206	GSE92742	MCF10A	Human	24h	0.4uM	EID0430

Response Information :

Types	Number	Response transcription factors
Up-regulation	110	TBP; ABL1; TXNIP; SETDB1; HOXD1; PIAS3; ZEB1; ARID5B; FOXO3; AR; SMAD4; PPP1R13L; FOXN3; TCF7L1; HBP1; PNRC1; ZBED2; ZNF117; KLF11; ARHGAP35; UBP1; NFE2L2; HIVEP1; ZFP36L1; ZNF135; CHD3; CREBL2; FOXF2; ZNF345; ZXDC; ZNF43; TADA3; SOX13; CDK9; NKX2-1; SOX11; ZNF682; NR2F1; ZNF232; SMARCA1; ARID1A; STAT4; JUN; ZNF12; SUPT3H; SCAI; ZNF586; FOXI1; SMARCD3; KLF7; ZFPM2; HLF; TLE2; AES; TAF11; ZNF623; SF1; COPS2; TRIB3; ZNF551; MEF2C; ZNF304; ZNF394; PCGF2; ZSCAN9; SOX2; BHLHE40; ILF2; NFKB2; TFAP2C; CBX4; CAMTA1; NR3C2; TCEA2; TBX3; ETS2; ZNF544; BAZ2B; NFE2L1; TRIM16; ZFHX3; ZNF83; FOXK2; ARNT2; CUX1; ZNF512B; KDM5B; NR4A2; SUPT4H1; BRD4; NLK; DMTF1; TGFB1I1; LEF1; PBX3; CITED2; FOXM1; IRF6; ZNF331; DAXX; TOX3; RBPJ; NFE2L3; ID2; TRPS1; MYBL1; HMGA1; MNDA; SHOX2; ID1
Down-regulation	109	ATF1; HMGA2; HEY1; PPARG; TLE1; MAGED1; RBBP7; CBX6; HOXA1; TCERG1; PURA; PDLIM1; ZNF443; TOB1; SUZ12; AATF; TAF9; ZNF274; MITF; ZHX3; ZNF266; NR1I2; ADNP; SMAD5; KLF5; ING1; HOXC4; TRIM28; HOXC6; NFIX; CARM1; ZNF222; MYCBP; SND1; NR1D2; ZBTB38; BRCA1; NR2F2; SIM2; JARID2; ZNF432; NAB1; IFI16; CBFB; ZNF24; BRD8; ZMYND8; GATA4; ZNF267; BATF3; BLM; GATAD2A; CTR9; EED; FOXC1; BAZ1A; HOXB7; SOX9; SNAI2; RNF6; MYRF; SMARCB1; MED1; ING3; TSC22D4; TAF10; PTTG1; HIC2; XBP1; ING2; IRF8; NFAT5; TBPL1; FOXJ3; STAT3; SOX10; PRKDC; LPIN2; ZNF226; ARNTL2; HLTF; TSC22D2; ZNF189; TAF1D; BMI1; PTRF; CRY1; NKX2-2; GATA6; TAF9B; HTATIP2; WT1; EGR3; FOXD1; SPIB; IRF7; EGR1; ASCL1; RNF141; EGR2; BHLHE41; HSBP1; CHD7; KDM5D; MSX1; CREB3L1; GATA2; MAFB; RELB