Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74599	Mk-2206	GSE92742	MCF10A	Human	24h	10uM	EID0430

Response Information :

Types	Number	Response transcription factors
Up-regulation	130	TSC22D3; FOSB; NCOR2; JARID2; FOXO4; CREG1; HMGA2; FHL2; TCF7L1; DDX17; KLF7; ZNF536; MAX; MNT; INSR; CREBL2; ZNF586; RNF10; TFCP2L1; TRAK1; NCOA2; CARHSP1; POLR2A; DAXX; AFF2; PBXIP1; IRF7; NRIP1; HIVEP1; HMBOX1; CASZ1; BTG1; NHLH1; SAP30; SOX4; PPP1R13L; CALCOCO1; EGR1; ADNP2; KDM4C; PDLIM1; MED15; ZNF768; RERE; HDAC5; LITAF; SREBF2; GTF2I; TRIM24; EP300; PHOX2B; MED14; RSF1; AFF1; ZBTB18; FOXN3; ZNF217; VDR; TLE4; TRIP4; KLF4; NR4A1; FOXJ2; ATF3; ARNTL; TCEB2; DNAJC1; MLLT10; RBPMS; YBX2; ZEB1; TSG101; ZMIZ1; ZIC3; TFEB; ARNT; ZFP36L2; KLF13; HIPK1; BBX; BRD2; BHLHE40; POU5F1B; TOB1; NCOA4; FOXJ3; SERTAD2; AEBP1; ETS2; ZNF131; DBP; NKX2-1; MAFG; PRMT2; NR2C1; TGFB1I1; ISL1; KLF2; SND1; ZFHX4; RUNX1; ZBTB43; HTATIP2; TFAP2C; NR4A2; PBX3; KLF6; AHR; BASP1; ID3; SMARCA1; PCGF2; TOX3; CREB3L2; BRD4; PTTG1; IRF4; LMCD1; GATA6; SMAD3; KAT2B; KLF9; CREB3L1; EGR3; SMAD2; MAF; ZNF532; LEF1; ARNT2; PSMD9
Down-regulation	114	CCNA2; TP53; CDK2; ACTL6A; TCERG1; SUV39H1; WT1; ZNF148; PIR; TTF2; EMX2; RUVBL1; CCNC; MYBL2; HMGB2; GTF2A2; NKX2-2; CEBPZ; HOXA10; CBX6; CCNE1; PSMC3IP; RUVBL2; ERBB4; ZNF576; NR1H4; TRIM28; HOXA11; MYNN; HOXB7; YEATS2; ZNF239; EZH2; PMS1; BANP; FOSL1; USP16; PHIP; TAF1A; SUZ12; IRF8; ZNF571; XRCC6; LHX1; HOXD10; BCLAF1; ZNF557; SMARCA4; TFEC; TEAD1; NFIL3; ECD; RBL1; BAZ1A; MSX1; MTF2; TRPS1; DLX5; ANKRD1; ZNF200; SMAD6; C1QBP; CENPF; RNF6; E2F8; APEX1; THAP1; HLF; NR2F1; SOX17; EN1; SMAD1; ZNF124; TEAD4; ARNTL2; SMARCD2; THAP10; HSF2; ZNF226; SLC2A4RG; TGIF2; BCL11A; ZNF652; RAN; SP140L; SATB2; CTNNB1; SOHLH2; MED24; ZNF91; HOXB6; ID4; YEATS4; PEG3; SCAND1; HOXB2; GFI1; MECOM; MYCBP; FOXA1; POU2AF1; HEY2; HDAC2; ZSCAN31; MYBL1; BHLHE41; NR2F2; TRIP6; EHF; ESR1; MEIS2; OSR2; PAX5; MEF2C