Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74553	Gsk-461364	GSE92742	MCF10A	Human	24h	2uM	EID0430

Response Information :

Types	Number	Response transcription factors
Up-regulation	147	WT1; AR; ZNF248; TGIF1; NFE2L2; ABL1; ZNF93; SPDEF; TFAP2A; ING4; FUBP1; TAF1A; ZNF12; SOX3; EP300; ZNF331; ZEB1; SOX5; ISL1; ZNF273; HESX1; NFKB2; TAF5L; MEIS2; ZNF350; ZNF141; HLX; NFE2L3; RARG; BNC2; NFIC; PRDM12; LIN28A; HIRA; GATA2; SOX13; E4F1; TEAD4; TRIB3; ZNF711; ARID5B; CALCOCO1; HOXB13; SIN3B; ZNF85; CREB3L2; YEATS2; SALL1; ZNF3; JUN; MYRF; SOX12; PITX2; PAWR; HDAC9; GTF2I; ZNF257; ZNF423; MED14; NANOG; SOX11; ID4; KAT7; NKX3-1; KAT8; ZNF551; NR1H2; CNOT3; ARID1A; NR4A1; ERBB4; EYA1; ZNF562; NCOR1; TLE4; CUX2; SCMH1; DAXX; TCEA2; ZNF500; HBP1; SMARCA1; UBE2I; TRRAP; OSR2; ZNF232; NR3C2; HOXB2; DMTF1; ZNF654; SMAD6; BHLHE41; CERS4; BRD4; KDM5B; ZBTB20; IRF8; ZNF43; ZNF117; ARNT2; AEBP1; URI1; SOX2; HIC2; POU5F1B; ZNF512B; CBX7; CBFA2T3; NFYC; ETV5; FOXM1; TSC22D1; TFEC; NR2F1; PBX3; REPIN1; SIX3; TGFB1I1; LEF1; PLAGL1; BACH2; BCL11A; HMGB1; PBX1; SOX17; ZBED2; ZNF532; BCL3; TBX3; KLF2; ATF3; BACH1; EMX2; ZNF107; TCF4; AES; NFE2L1; HHEX; SOX9; KLF11; TOX3; TRIM29; MNDA; MYBL1; ID2; ESR1; ID1
Down-regulation	172	CRK; ATF1; CBX6; HEY1; BMI1; MTDH; ASH2L; TBP; ARID4A; HOXA5; ADRB2; YAF2; BRD8; SMARCE1; TOB1; FOXC1; ZHX3; SMARCA2; TCF20; SAP30; NR0B2; CEBPA; HOXA10; RHOA; NRBF2; HIPK3; PDLIM1; KAT6B; MBD2; TMF1; NR2E1; RFX5; DR1; PHF20; RUVBL2; TERF2; SOX4; MYB; HMGA2; MED6; ADNP; UBP1; NCOR2; NCOA4; HCFC2; TAF4B; ZNF292; NR1I2; TOX4; MED1; IKZF5; BRCA1; POU3F2; CBFB; THAP1; ESRRA; NFIB; ZNF177; VEZF1; HOXA1; HIPK1; AATF; SUZ12; ELK1; FOXJ3; TAF11; HOXC6; CEBPD; SREBF1; TOX; EGR1; ELF5; FOXA1; CTR9; PLAGL2; ARNTL; ING3; PROX1; HLTF; TSG101; SNW1; PHF8; MED20; STAT6; IRX5; BRF2; ZNF165; SIM2; MSX1; BCL11B; C1D; RNF6; WWTR1; PSMD9; COPS2; PTTG1; PITX1; AHR; ZNF432; TAF9B; TOPORS; ETS1; NR2F2; STAT3; NR1D2; NONO; BAZ1A; CRY1; BTG1; ABT1; FOXD1; TBPL1; PQBP1; TCF12; RUNX1; POLR2A; ZMYND11; NR2C1; SNAI2; SKI; TRIP6; ZSCAN31; NFKB1; PFDN5; PEG3; NUP62; TSC22D2; SCAND1; SUB1; ECD; ZBTB38; TCF21; EED; NR0B1; EGR3; ERG; PURA; GATA4; MED24; CCNC; ASCL1; PEX2; TAF10; MLXIP; KLF9; YBX1; HMGN3; NKX2-2; ETV1; NAB1; PSIP1; FOXF1; ZNF226; HES1; KLF10; MECOM; ELK3; ZNF131; HMGB3; LPIN2; SMAD1; MAF; SMAD3; ETS2; ZBTB18; MEIS1; BRD2; FOXO1; TRPS1; RBPMS; E2F2; MEF2C