Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74552	Gsk-461364	GSE92742	MCF10A	Human	24h	10uM	EID0430

Response Information :

Types	Number	Response transcription factors
Up-regulation	142	ZNF711; NFE2L2; CEBPZ; RREB1; ZNF248; HLX; IRF9; PHIP; PAX8; HNF1A; BCL6; GTF2I; SPDEF; KAT8; SALL1; NFYC; ZNF7; ZNF444; NR2F1; MNDA; NFKB2; ZXDC; NR4A2; ARID5B; UBE3A; ZNF16; FUBP1; HIRA; PKNOX1; ID4; STAT2; ZNF12; INSM1; AR; E4F1; ARNT; PML; TFAP2C; TADA3; YEATS2; SATB2; MAML1; SIX3; BCLAF1; ZNF611; REL; TXNIP; IRF8; ZNF394; SAFB2; HDAC4; KLF3; MDM2; LEF1; CLOCK; REPIN1; FOXA2; EPAS1; DEAF1; CBX7; HDAC5; WT1; YAP1; ZNF22; PNRC1; RBPJ; HOXB13; SMAD4; DMTF1; CTCF; TRIB3; ZNF273; CDIP1; ZNF467; HDAC1; CUX1; TOX3; KLF4; DAXX; ESR1; ZNF195; CSDE1; BHLHE41; TBL1X; MAFB; MAF; SOX2; BCL11A; HIVEP1; KMT2A; IRF6; EDF1; CREBZF; ZNF43; TCEA2; ZNF83; ZKSCAN1; BACH1; SOX11; CBFA2T3; PRMT2; NFYB; TBL1XR1; GTF2F1; TRPS1; EMX2; BAZ2B; CHD7; ZNF44; PIR; ZNF512B; MEIS2; KLF9; SP140L; CHD9; ZHX2; ETV5; ZNF232; CD3D; ERBB4; ZNF160; ARNT2; TRIM22; TFEC; ATF3; TBX3; ZFPM2; JAK2; TRIM29; ETS2; POU4F1; DACH1; ZBTB20; AES; HMGN3; PBX1; CREB3L2; ZNF652; ZNF91; ID2; RBPMS; HOXB2
Down-regulation	154	ATF1; MAGED1; HOXA5; DLX2; SOX4; ELK3; KDM5C; PDLIM1; MED31; STAT6; CALR; TMF1; ADRB2; DR1; ZNF177; NR1I2; BMI1; KAT2A; ELF1; HMGA2; ORC2; JARID2; SOX15; AATF; EGR4; ELK1; YAF2; HOXA10; ZNF226; BHLHE40; TEAD1; ZSCAN12; ARNTL; MYB; FOXD1; HOXA1; BAZ1A; SMARCA4; TGFB1; RXRB; SMAD7; SUZ12; RBBP7; RCOR1; HOXA7; MTDH; RBL1; LOXL2; RUVBL1; ERF; CARM1; IRF4; RNF6; TOB1; BBX; ZNF222; ATF5; MED20; ERG; C1D; TFAM; APEX1; SIM2; PRKDC; CEBPD; ZNF562; NCOA2; THAP1; HMBOX1; HOXB7; PLAGL1; SAP30; ABT1; TBPL1; HOXC6; SIN3B; MED4; LMCD1; ZNF184; TRIM27; CIC; EGR1; BATF3; ASH2L; XRCC6; E2F3; BRF2; ZFP36L1; CBFB; RFX7; STAT3; POU3F1; FOXC1; MED1; SMARCA5; DDX17; KMT2B; ZNF329; ASCL1; NONO; BTG1; GATA4; TSC22D4; RUNX3; CBX3; HMGA1; SPIB; RB1; HOXC4; BCL11B; SCAND1; WWTR1; PEX2; ZBTB1; HDAC9; ZNF165; ZSCAN18; ING2; KLF7; EED; ZNF593; DDIT3; GLI3; ELF5; PQBP1; HSF2; MYCN; SMARCA2; CRY1; KAT2B; NFIB; ZNF131; SNAI2; PTRF; MEOX1; NR0B1; NFAT5; HHEX; ID3; BRD4; TRIM16; TWIST1; ZEB2; EGR3; HLTF; ETV1; BASP1; ZBTB18; JUP; POU2AF1; PAX5; MYBL1; E2F2; MEF2C