Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74529	Azd-7762	GSE92742	MCF10A	Human	24h	10uM	EID0430

Response Information :

Types	Number	Response transcription factors
Up-regulation	155	STAT5B; GLI2; HOXD1; FOXO4; HOXD3; IRF9; NFKBIA; PNRC1; BTG1; L3MBTL1; CREBL2; CNOT3; MYB; CDX1; NCOA2; SETDB1; HBP1; ZNF444; HSF4; ARL2BP; TFAP2A; CALCOCO1; BAZ2A; ZFPM2; TADA3; ZNF358; ZBTB7A; ZKSCAN1; TFEC; JUP; GATA6; INSR; ZNF586; TGFB1I1; TRIB3; ZNF12; CREG1; OLIG2; ARID5B; ZNF688; NFE2L2; TCF15; KAT2A; KLF5; TCEB2; NFATC4; MMS19; ARID1A; PHF1; HINFP; HSF1; STAT5A; ZNF175; ZNF768; WIZ; FLNA; SP1; CBX7; HIVEP1; ELF4; ZNF141; TOX3; ZNF217; CAPN15; NHLH1; ZEB1; MED13; HDAC9; TRIM29; IRF7; BPTF; SIX3; HMX1; FOXA2; ST18; NR2C1; EHMT2; ZIC3; LDB1; BRD4; KLF3; NANOG; SATB2; ERBB4; RYBP; SP2; NFE2L3; SMARCC2; SOX13; ZNF423; BNC2; ZNF580; TLE4; TSC22D1; SREBF2; AES; TCF7L2; FOXF2; PSMC3; KMT2A; VPS72; WT1; KAT2B; INSM1; TRIM22; NFE2L1; ZNF264; ZBTB20; TCF12; MYRF; CHD4; GFI1B; MAF; OSR2; ZNF551; TFCP2; ID4; ZNF91; EMX2; ZNF195; ARNT2; ZNF117; GTF2F1; KLF13; TDP2; MITF; BCL11A; ZFP36L2; BHLHE41; KLF11; KLF7; ZNF83; IRF6; MNDA; TP63; SUPT4H1; AHR; MYCL; PLAGL1; TFAP2C; ZBTB16; MYCN; ATF3; ZHX2; LYL1; DACH1; SNAI2; REPIN1; TRPS1; BRD2; PBX3; MECOM; POU2AF1; HIF1A; GMNN
Down-regulation	176	TP53; CCNA2; HMGA2; SUV39H1; ADRB2; DNMT3B; MAGED1; RBM14; NRIP1; CEBPZ; TBP; TRIM32; TCERG1; MNAT1; TMF1; TSC22D2; PSMC3IP; SFPQ; RBL1; ORC2; CBFB; PPARG; RUVBL2; EZH2; RBBP5; ING1; TCFL5; CBX5; CHAF1B; ZNF45; BRCA1; TEAD1; ZNF23; ELK3; PURA; ECD; WDHD1; MED6; HNRNPD; SMAD5; TCF7L1; NR2F2; ZNF226; ZNF783; PAXBP1; FOSL1; WWTR1; FOXC1; GCFC2; TGS1; IRX5; TRIP6; SIM2; HOXC10; ZFP37; PIAS2; BAZ1B; HOXC6; ITGB3BP; HOXA1; TFAM; MED7; JARID2; POLR3F; EED; CNOT2; CCDC59; TCEA2; CITED1; WWC1; HLTF; SMAD1; ZNF468; MTF2; TRRAP; GABPB1; SSRP1; SAP30; SUMO1; PITX1; ZNF32; CBX6; CTNNB1; HOXD11; LHX6; TBL1XR1; BRD3; CARHSP1; BCL11B; THAP1; CHD3; NR1D2; NKX2-2; CCNE1; RNF14; RREB1; YWHAB; RXRA; TTF1; BTAF1; RBBP4; SOX11; BATF3; C1D; MYNN; REL; NPM1; HES1; CREBZF; BRIP1; TOPORS; ARNTL; SALL1; CENPF; ZNF721; YEATS4; CRY1; SIX1; DLX2; ZNF410; ADNP; ZNF107; TCEA1; PTTG1; FOXA1; MSX1; CHD7; IRF2; FOXG1; HOXD10; YAP1; NKX3-1; ZNF239; HMGB2; NFIC; SMARCA4; AFF1; PRKDC; IRF4; HOXC4; SMARCD3; ZNF532; NONO; CTR9; LHX1; ID3; ZIC1; CCNC; SUB1; THAP10; EGR3; BASP1; SIX2; ELF5; BMI1; ZNF131; GRHL2; NR0B1; E2F5; SKI; RAN; RUNX1; TLE2; ID1; KLF10; IFI16; ETV1; NFIB; SIAH2; SMARCA1; LEF1; GATA2; MAFB; ID2; MEF2C; E2F2