Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74527	Barasertib-hqpa	GSE92742	MCF10A	Human	24h	0.4uM	EID0430

Response Information :

Types	Number	Response transcription factors
Up-regulation	345	HDAC6; NFATC4; PPARD; MYBL2; PAX8; TCFL5; GLI2; STAT5B; LHX3; SOX2; TCF7L1; EP400; ZNF573; BRPF1; TGFB1I1; RXRG; ZNF75D; BRWD1; TGIF1; ZNF473; SOX5; PRDM2; WWTR1; LIMD1; ZNF778; UBE3A; EMX1; MECP2; TLX3; TFEB; SOX13; AEBP1; CEBPA; TAF7; RNF10; PROX1; ZNF253; ZNF500; CBX2; OVOL1; HLF; FOXN3; POU2F1; ZNF93; CSDC2; SOX21; NRL; FUBP1; ZNF202; RARA; STAT2; KDM4A; MBD2; PBX2; TADA3; FOXO3; TAF4B; YWHAB; SALL1; ZNF175; NFYC; PIAS1; PRDM14; ZNF189; KLF15; BCL6; ZNF557; PCGF2; GATA6; HOXD11; KLF11; UBTF; ZNF419; FOXB1; ZBTB48; LITAF; ZNF136; ZNF324; CAMTA2; SOX11; EYA1; SETDB1; CDK9; TEF; NR1H4; NKX2-5; ARNT; NHLH1; NCOA1; ZNF444; CHD2; TDRD3; CAPN15; HOXD13; PHIP; SSBP3; CRYM; ZNF248; TERF1; BCL11A; NR5A1; IFNB1; HDAC11; SLC2A4RG; CREM; ZNF217; HSF4; SNAI1; ZNF510; TULP2; BARX1; FOSB; INSM1; ZNF586; TFCP2L1; PRDM5; HIC1; RREB1; OLIG2; SRY; CREBL2; INSR; CREB5; ZNF446; BPTF; ZNF665; MEN1; ZNF263; CBL; ZNF835; NFATC1; MAP3K10; MZF1; ZNF140; PBXIP1; MBD1; ZNF550; HOXC11; KLF4; ZIC3; BCL10; TEAD3; GRHL2; ZBED1; NCOR2; ZNF343; ING4; HNF1B; TAF1D; PITX3; ZNF268; PREB; DLX4; ATOH1; ZNF141; KMT2A; SP140; NEUROD1; LZTS1; ZNF12; TCF7; AFF2; SPI1; ZNF177; FOXI1; LHX2; ZNF701; OSR2; SPIB; ZNF174; ZNF286A; ETV5; IL16; CCNT1; REL; CAMTA1; TULP4; TRIB3; NFYB; NR4A1; ZNF331; FOSL2; ZNF211; CREB3; WWP1; GCFC2; NANOG; ZMIZ1; CBX7; CDX1; ZSCAN16; PURA; SCRT1; NFX1; HOXB13; MLLT1; NR2F2; KLF7; SUPT6H; ZXDC; MNDA; FOXO1; PRDM10; POU2AF1; IRF7; RARG; KLF13; PAX5; SP110; PHF20; EED; RNF138; ZBTB44; RFX2; NCOA6; KLF12; ZNF391; ZNF124; DDX17; HDAC4; AATF; ZBTB14; NKX2-1; ZNF512B; ZNF85; ZNF184; KAT8; ZNF682; TRIM24; BAZ2B; BBX; NFKB2; CREB3L1; FLI1; ZNF423; SP100; ZNF711; TSC22D2; ZNF83; ZNF232; ZNF257; LIN28A; NLK; ZNF250; TFAP2C; ATF3; PLAGL2; SATB2; VGLL1; NR2F1; AES; BNC2; EZH1; BRIP1; DAXX; HMX1; POLR3C; TAF9B; NR4A2; ZBTB43; ETV6; YBX2; ZNF467; BRD2; SMAD2; PRRX1; HESX1; PHF1; ELF4; ZHX2; IRF9; SUPT3H; NR1H3; PKNOX1; ETV1; NFYA; RERE; KLF3; TRIM22; TXNIP; ZNF544; SPDEF; HR; GATAD2A; ZFHX3; PKNOX2; NCOA3; CBFA2T3; DBP; KLF10; MAF; ZNF33B; ZNF606; FOXE1; MLX; ZNF274; ZNF44; EMX2; ZSCAN31; CARM1; GTF2F1; YAP1; POU5F1B; ZNF273; IRF3; TFDP2; LPIN2; NHLH2; TCEA2; PBX1; ZNF91; POU4F1; ZNF112; ZFPM2; NR3C2; ZNF195; ZNF611; CARHSP1; PQBP1; LHX1; HMBOX1; EYA2; SIX3; SERTAD2; MLXIP; RING1; MECOM; BASP1; IRF8; CHD7; ETS2; BRD4; GTF3A; KLF9; MED24; ZNF281; ASCL1; EGR2; LYL1; TLE2; SMAD1; MAFB; ID2; TWIST1; HIF1A
Down-regulation	344	CDK7; PCBD1; GTF2A2; FHL2; MYC; ATF6; RHOA; TFAP2A; RUVBL2; NFKBIA; DNMT1; HMGA2; MAGED1; NR2F6; PUF60; ATF1; CCNH; SSRP1; MAZ; DR1; WHSC1; ARNTL; HDGF; FOS; TRIM28; SOX15; PRKDC; TFDP1; HOXB6; THAP4; ELK3; KDM5A; RFC1; MDFI; TEAD1; ZNF576; CCNE1; HOXB9; HOXA1; MED15; YEATS2; TCF25; TTF2; WDR77; ID3; ZNF32; ATF2; RNF4; NFE2L2; CBX6; CDYL; CENPF; HOXB3; HMGB1; TRRAP; C1D; HOXD1; ZNF593; NEDD8; HLX; ELF3; BRD8; ZBED4; HSBP1; LZTR1; CDK8; NONO; TRIM32; GTF2A1; PFDN5; ZNF426; SMAD5; MXD4; HOXB5; HBP1; ARID1A; TMF1; ARL2BP; PITX1; UBE2L3; TRAK1; PTRF; HMGXB3; PPARG; APEX1; SOX12; CBFB; XRCC6; POLR3F; GMNN; PEX14; SUB1; HMGXB4; BTF3; ZNF302; CTR9; SRCAP; SIRT7; CITED2; THAP11; NPM1; SP3; SREBF1; ZFP64; SETD2; HIPK2; ZNF205; BAZ1A; MKL1; BLZF1; BAZ1B; VSX1; RNF2; NACA; SSBP2; ZFP36L1; TAL1; TP53; HAND1; KDM2A; TAF12; RCOR1; ELK4; MITF; TFCP2; E2F3; ZNF432; PMF1; RUVBL1; PSMC3IP; KLF6; COPS5; YBX1; MED27; SAP30; TCEB2; CTCF; HIC2; SUMO1; ZKSCAN5; PLAGL1; TBP; ZNF639; PCGF3; ENO1; ZNF224; HOXA10; HOXA7; DPF2; TCF12; MXI1; THRA; DEK; MED7; PITX2; ARID4A; NELFB; DDX5; MED21; ZNF226; ZBTB40; HLTF; BANP; TRPS1; PNRC1; JARID2; ZNF516; DRAP1; ZNF692; MED6; ZMYND11; HOXB2; NSD1; PAXBP1; HOXB7; SMARCD3; ERCC3; ADNP2; HNRNPD; RYBP; ATF4; MYB; TRIM29; TRIP6; NR3C1; SPEN; KAT6B; SMAD6; ADNP; UIMC1; IRX4; REST; TOX; ZNF587; RFXAP; PHF8; PRDM12; FOXC1; CERS6; ZNF468; ZNF408; NCOA4; ILF2; NR2C1; MED4; RAD21; MTDH; RUNX3; CD3D; SREBF2; MXD1; ERBB2; CNOT1; SFPQ; YAF2; NFAT5; FOXJ2; TGFB1; AGO2; NFKBIB; CEBPG; MYT1; EDF1; WDHD1; NFKB1; TLE4; NOC2L; BTAF1; ZBTB39; ELK1; ID1; MYF6; POU3F2; PIR; HDAC1; ZNF74; YEATS4; POU2F2; CIC; BRF2; BRD3; ESR1; TCF7L2; CITED1; PGR; HEY1; TAF5; RCOR3; SOX4; SMARCA5; HDAC9; KAT2B; PBRM1; RRN3; ESR2; CCNC; MYCBP; TBL1XR1; VEZF1; MNT; THAP10; KLF1; NFE2L1; ELF2; HDAC5; HOXC4; RNF141; SOX9; POLR2A; ZNF354A; HOXA11; ZNF43; BRCA1; FOXF1; CREB1; ISL1; SIX2; MSX1; ZNF562; CTNNB1; SIRT2; SND1; TULP3; RNF6; CHD4; CRY1; HTATIP2; MEIS2; TERF2; RAN; BRD7; PRRX2; BATF3; TSC22D4; FOXM1; CUX2; NFIL3; VDR; ZNF264; ZIC1; ZFHX4; VPS72; STAT3; HDAC2; ZNF532; TFEC; JUND; ARNT2; IFI16; FOXD1; SMARCA1; NFE2L3; FOXF2; RBL2; ERG; HIRA; BHLHE40; RBBP8; SHOX2; PTTG1; MED1; JUNB; C1QBP; HHEX; KDM5B; RBPJ; ZBTB18; SNAI2; HEY2; EN1; FOSL1; CREB3L2; ZBTB16; HMGB3; MEF2C; KDM5D; BHLHE41; NFIB; PEG3; RELB; TBX3; NFATC3; DACH1; E2F2