Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74526	Barasertib-hqpa	GSE92742	MCF10A	Human	24h	2uM	EID0430

Response Information :

Types	Number	Response transcription factors
Up-regulation	112	MTA2; MDM4; KDM5D; RBBP5; HEY1; TLE4; PBXIP1; TCF7L1; CDK9; HOXB13; GRHL2; ZNF345; LITAF; SAFB; ZFY; ZNF93; STAT2; ZNF586; CSDC2; NFATC1; AR; TCF4; ZNF117; DLX5; BCOR; POU2F1; ARL2BP; ISL1; DDX17; BCL11A; USP21; INSM1; SPI1; EYA1; FOXF1; SOX11; NR2F1; CSDE1; ZFHX3; NCOA2; ZSCAN18; WWP1; FOXN3; CBFB; TXNIP; SMARCA1; KLF13; ZNF721; CALCOCO1; ZSCAN16; PBX2; RBBP4; EZH1; PAX6; LIMD1; YBX3; IRF6; IRF3; TBL1XR1; NONO; BTG1; ZNF124; PFDN5; ZNF160; CAMTA1; CNOT1; PBX3; CUX2; ZSCAN9; AES; BBX; TDP2; HMBOX1; TRIB3; ZNF33B; ZNF232; LOXL2; CHD9; CTNNB1; ZNF410; TCF7; REPIN1; ZNF611; FOXA1; ARNT2; TFDP2; DMTF1; TGFB1I1; ZNF331; ZNF652; ZSCAN31; ZNF107; RBL2; NKX3-1; TCEA2; DACH1; NKX2-1; KLF9; NR0B1; TRIM22; TRIM16; ID1; HSBP1; MAF; AEBP1; ZNF512B; JUND; ZFP36L2; POU4F1; MEIS2; NFKB2; TBX3
Down-regulation	122	FHL2; ATF6; TFAP2A; TFDP1; NEDD8; TRAK1; KDM5C; SAP30; MTDH; MAGED1; TP53; FLNA; TTF2; NRBF2; ZNF7; ZNF384; ZNF552; MKL1; KDM2A; RUNX3; FOSL1; MED15; NCOR2; TFE3; TRIM32; EGR3; BRCA1; NPAS2; ENY2; NFKBIB; ERBB2; WT1; TRIM25; TMF1; STAT5A; ZEB2; CHAF1B; UBP1; BRD8; REST; MED6; PDLIM1; HOXA1; RNF10; MITF; DDX54; USF2; TAL1; WDHD1; BLM; NR1H3; BCL10; ARNTL; VEZF1; RFXANK; MXD1; HMGA1; SERTAD2; JARID2; IRF5; ASH2L; HOXB7; RBBP7; RBBP8; SNAI2; PSMD9; MLXIP; MED1; PPARGC1A; NFYC; ELK3; NUP62; PRKDC; HSF2; TRIP6; TRIM29; ZNF32; ZNF593; FOXC1; IRF4; RCOR1; BATF; MAFB; STAT3; ZNF274; PIR; EMX2; ELF5; EGR1; ST18; NFE2; ETV5; ZNF146; TCEB2; ZNF267; BHLHE41; PEG3; SMARCD3; IFI16; SMAD1; TGFB1; EED; EGR2; MXI1; NFIL3; HDAC2; PLAGL1; MEOX1; TSC22D1; SIX2; RNF141; NFIB; HLTF; KLF4; KLF10; MNDA; MYBL1; ID2; FOXG1; POU2AF1; RELB; E2F2