Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74522	Saracatinib	GSE92742	MCF10A	Human	24h	2uM	EID0430

Response Information :

Types	Number	Response transcription factors
Up-regulation	136	GLI2; MNAT1; ABL1; MTA2; EP400; MYBL2; TXNIP; ZNF586; CREB5; RBBP5; NEDD8; EN2; TRIM16; BTG1; ZKSCAN4; RXRA; NCOA1; SAP30; BBX; NSD1; NCOA6; RBBP4; ZNF506; ZNF93; PLAG1; STAT6; STAT2; ZNF587; RBM14; CSDE1; E2F2; GTF2IRD1; ZNF202; HOXA11; CDYL; BRCA2; KMT2A; TEAD1; SMARCA2; NRF1; SMARCB1; THRAP3; GLI1; CALR; NCOA2; NR1I2; FOXF2; PRDM10; SERTAD2; CTNNB1; MDM4; LIMD1; TRIM27; ZNF224; ZBTB38; HSF2; URI1; TAF4; NR0B1; ZNF217; ELF1; MED13; ZBTB11; TRIM25; ZSCAN16; PHF20; CAPN15; ZNF91; RNF14; CCDC59; NR1D2; LMCD1; TSC22D3; RARA; RLF; PIAS4; TOB1; IRF9; HIVEP2; PBRM1; SATB2; TCF15; ZNF430; GATA4; MED1; UBE2I; MSC; RBM39; ZSCAN18; RFX7; MLX; ZNF552; BRIP1; MAGED1; ZNF143; LOXL2; E2F3; ZMIZ2; BLM; NCOR1; MYRF; ZEB2; FOXL2; HDAC1; DDIT3; SIAH2; AES; IRF4; PITX1; AEBP1; TLE2; FOXN3; MEOX1; EHMT2; KLF5; FOXD1; ASXL1; C1QBP; ARNTL2; SMARCD3; MSX1; TGIF2; TRIM29; PURA; ZNF423; CREB3L1; IRF6; ZHX2; POU4F1; KDM5D; ZBTB20; TWIST1; JUP; PBX3; HDAC2; PSMD9
Down-regulation	132	HOXD1; HEY1; ARL2BP; HMGB2; MTDH; HIF1A; RBPJ; ZFP36L1; ENY2; ESRRG; CITED2; CEBPB; ZNF3; ZNF7; NR2F1; CBFB; ARNT2; ZNF696; IFI16; SMAD1; HMGB1; BCL3; ZBTB17; TGFB1; NELFB; ISL1; HBP1; PEX14; ZBED2; CHD3; ELK3; ZEB1; ZNF468; TCF25; HOXB2; SUZ12; ESR1; PIAS1; NFKB1; THAP10; MXI1; ID3; NFIB; ZNF623; PA2G4; NONO; MEIS2; DNAJC2; ZBTB43; ERG; WWTR1; XRCC6; ZNF34; NR1H3; BHLHE41; NHLH2; YEATS2; RBPMS; SUB1; ID1; ZNF512B; RNF138; NR1H4; TRPS1; TCF4; SP100; ZNF721; DEK; USP16; TAL1; TGIF1; NKX2-1; IRF1; SALL2; RUNX3; HOXB13; HIC2; PCGF2; FOXA1; YBX1; MAFG; SOX2; EGR2; HIPK1; TCEA1; EPAS1; JUN; HHEX; PCGF3; HLF; HIRA; TEAD4; ENO1; ZNF274; FOXG1; SALL1; YBX3; INSR; PTRF; CTBP1; GTF3A; NR4A1; RBBP8; ID4; CREB3L2; MAF; ZNF22; NR4A2; SMARCA1; RYBP; NAB1; WT1; FOXK2; ZNF264; TCF7; SOX17; KLF6; HOXB7; ZBTB16; ZFPM2; CHD9; HLTF; ZNF331; EGR3; EMX2; MYCN; TBL1X; TFAP2C; KLF4; SOX11; ID2; MEF2C