Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74521	Saracatinib	GSE92742	MCF10A	Human	24h	10uM	EID0430

Response Information :

Types	Number	Response transcription factors
Up-regulation	125	TSC22D3; CEBPA; STAT3; FOXO4; HOXD1; PBXIP1; CREG1; FOXO3; FOSB; PNRC1; ZNF358; ARID5B; BCL3; NFKBIA; SSBP2; OVOL2; ZNF586; TP53; MZF1; ZNF141; TXNIP; HOXA5; CREBL2; ZNF268; ZNF91; TFDP2; EP300; CALCOCO1; NFE2L2; IRF9; LITAF; ZMIZ2; ZNF467; ZNF148; REL; ZNF580; FOXN3; SIM1; ARID1A; ELF3; SSBP3; NCOR2; ARHGAP35; HOXB13; IRF7; HMBOX1; AES; DDX17; HDAC4; ZNF12; NFIL3; PHIP; AR; SETDB1; REPIN1; ATF3; ZIC3; PPARGC1A; SREBF1; GATA6; CHD3; TFAP2C; SREBF2; ZNF44; MDM4; BTG1; WNT4; HDAC5; RXRA; ZNF160; TBPL1; SMARCD2; SND1; ELF4; SALL2; PBX1; ZNF232; KLF4; YEATS2; SAP18; CNOT1; RORA; ZNF33B; BRD4; ZNF544; GTF2F1; ZNF117; NFIC; YBX3; NFE2L1; EMX2; RBL2; ZKSCAN1; IRF6; ID3; ZBTB16; NR4A2; INSM1; NR4A1; NKX2-1; TCF7; ZMIZ1; OSR2; BRD2; ETS2; INSR; MECOM; BCL6; SMARCD3; TCEA2; TOX3; JUND; KLF11; TBX3; ID1; ARNT2; ZNF331; ZNF652; TRIM29; LEF1; JUP; KLF9; FOXG1; MAF; PSMD9
Down-regulation	123	TCERG1; CCNA2; HMGA2; SUV39H1; MYBL2; HMGB2; BRCA1; TRIM32; CEBPD; CENPF; EZH2; C1D; ATF5; SAP30; TAF1A; PTTG1; PSMC3IP; CEBPZ; PPARG; PIAS3; GABPB1; IRF8; TAF5; GTF2A2; BMI1; RBM14; TBP; RBL1; BLM; RNF4; ELK3; TTF2; XBP1; NFKBIB; MED7; ZNF200; MAGED1; TRIM25; YAF2; TRAF6; WDHD1; MTDH; MED20; SMAD7; HMG20A; SSX1; MED17; ARNTL2; BHLHE41; CHAF1B; PPRC1; HHEX; SOX9; WWTR1; ARNTL; EGR1; ZNF528; SIM2; ETV5; BAZ1A; ING2; PREB; BCLAF1; PAX6; CNOT6; SP3; TERF2; AGO2; CBFB; RUNX1; NRBF2; PTRF; FOSL1; HOXA1; RNF6; ZNF274; EED; BHLHE40; ASH2L; DNAJC2; LOXL2; TCF21; RNF138; DLX2; HIPK3; PRRX1; ZNF143; BATF3; ZNF552; PEG3; ETV1; ZEB2; SOX4; ELF5; CHD7; ZBED2; TLE4; NKX3-1; HOXC6; FLI1; NR2F2; TGFB1; HSBP1; FOXF1; FOXM1; ZNF189; NPAT; FOXD1; CRY1; MSX1; POU4F1; SUZ12; EGR3; EGR2; HOXC10; TCF4; MNDA; SUB1; ERG; MEIS2; BASP1; POU2AF1; E2F2