Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74518	Azd-6482	GSE92742	MCF10A	Human	24h	2uM	EID0430

Response Information :

Types	Number	Response transcription factors
Up-regulation	115	PPARG; CREBL2; CREM; BNC2; NFE2L3; CEBPZ; SAP130; MED14; NANOG; BCL3; IRF9; SPDEF; CHD4; ZNF180; DLX4; TGIF1; TCF7L1; BCOR; AR; NFKB1; PRDM14; TFEC; RELB; BPTF; NR1H3; ZBED2; CNOT2; HESX1; RELA; NR4A3; HOXB13; ZNF350; PHIP; TERF1; ZNF273; WWP1; ARID5A; REL; HIVEP1; ZNF331; NR2F1; ZEB1; NR4A1; NFATC1; ZIC3; ZNF544; ZFPM2; SUPT3H; TRIM24; LIN28A; PBXIP1; ZNF3; LMCD1; SMARCA1; CERS4; FOXO1; RERE; SPIB; SOX13; SCMH1; MAF; HIPK1; NR1H2; IRF7; PRRX1; SATB1; TRIM22; CRYM; ELF3; JUN; ZNF232; CITED1; LITAF; NFYC; SALL1; ZNF195; ARID5B; TBL1X; ZNF267; HIRA; ETV5; NR4A2; SNAI2; OSR2; SOX2; BACH2; ZBED1; HHEX; PQBP1; LOXL2; TRIB3; IRF1; ARNT2; TCEA2; JAK2; PIR; YEATS4; ZHX2; C1QBP; NFKB2; ZNF107; HIC2; MYCL; KAT2B; CREB3L1; JUP; NKX3-1; PSMC3; MEIS2; PBX1; TRIP6; EGR2; AEBP1; FOXG1; POU2AF1
Down-regulation	127	MTDH; MXD3; DDIT3; NCOR2; TADA2A; IRX5; PSPC1; MAZ; UIMC1; NCOA6; EP400; KDM5C; HEY1; POU3F2; BANP; HCFC2; SAP30; SERTAD2; ZNF276; PEG3; TOX4; TAL1; MAX; FOXC1; ZNF23; CCNE1; GABPB1; IKZF5; AGO2; ATF4; MEIS1; KAT6A; TRIM25; BRD8; YWHAB; RNF10; SUZ12; CBX6; TSC22D2; MSX1; CDK2; KDM2A; BHLHE40; SMARCE1; TXNIP; RAD21; CRY1; PDLIM1; CCNC; PHF20; CEBPG; HR; MED1; ARRB1; TERF2; YAF2; BMI1; MBD2; PSMD9; MXD1; MED20; MED24; HOXA1; SOX10; SMAD7; CARHSP1; HLTF; ZNF536; MXI1; HMGB2; HTATIP2; CHD3; SMAD1; VPS72; PMS1; MLXIP; SMAD6; PA2G4; PAX6; PURA; RNF111; BRCA1; BTG1; ELK3; BTF3; SNW1; GLI3; NKX2-2; MAFB; WWTR1; NHLH2; HIPK3; ID3; RAN; HMBOX1; ING2; SCAND1; NCOA4; EED; NR2F2; ANKRD1; PCGF1; PTTG1; SMARCA2; ZNF266; MECOM; SUB1; DACH1; HDAC2; SMARCC2; RNF141; AIP; ZEB2; JUND; TOB1; MYCN; BRD2; CHD9; NFIB; KLF6; ERG; HOXC6; TWIST1; ZFP36L2; KLF10; ID2; E2F2