Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74517	Azd-6482	GSE92742	MCF10A	Human	24h	10uM	EID0430

Response Information :

Types	Number	Response transcription factors
Up-regulation	204	ZNF711; EGR1; ZNF350; ZNF268; ST18; ZIC3; HIVEP3; ZFPM2; ACTL6A; ACTL6B; CHD2; TFAP2A; RBFOX2; ZNF93; FOSB; PRDM14; ZNF85; ZKSCAN4; FOXN3; MED14; NFE2L3; ZNF345; REL; E2F8; NR2F1; HOXB5; ZNF141; ZNF443; ZNF43; AFF2; ZIC1; NFE2L2; SMARCA1; BRWD1; MZF1; ZNF682; HOXD1; ZKSCAN7; ZNF223; LZTS1; ARID5B; ZNF835; HIPK2; VPS72; ZNF623; MED12; SETDB1; SETD2; KAT5; NKX3-2; ZNF273; ZBED1; IRF1; NEUROD1; ZFP37; ZNF586; TAF7; EP300; SCMH1; TRIB3; HMGXB4; GRHL2; ZNF654; NR2C1; WT1; ZNF214; ATF2; ZFHX3; MECP2; ZNF467; ZSCAN9; ZNF239; RELB; TEAD3; FLI1; NHLH2; NAB2; HOXB6; TGIF2; TCEA2; DAXX; ZBED4; ZNF140; SALL2; ZNF250; ZNF665; ZNF136; RARG; PKNOX2; E4F1; SMAD4; ZNF606; ZNF544; SIX6; ZNF117; POLR3C; CBFA2T3; PHIP; AES; ZNF415; ZNF304; ARID1A; TLE2; RAD21; POU4F2; CAMTA1; ARNT; NFKB2; HBP1; ZNF331; ZNF512B; ZNF22; IRF6; MYT1; ZNF551; SRF; INSM1; TCF25; HOXB13; RREB1; IRF9; NKX3-1; CUX2; CREM; FOXA2; GTF2IRD1; NFYC; PIAS4; ZNF432; ZNF32; HDAC5; HDGF; PEG3; CTCF; LIN28A; KLF3; ARID5A; SREBF2; ZNF423; THAP10; ZNF232; SOX2; SOX13; RSF1; MEOX2; TAF11; ZNF124; TDP2; TEAD4; AR; NFAT5; JUN; ZNF195; TBL1X; PHF20; BCL6; ARNT2; TSG101; PAX6; ZNF33B; RXRA; ZNF354A; MEF2C; BNC2; ZNF12; CCNE1; NANOG; ZEB1; BHLHE41; ZNF264; ZNF667; KLF7; KLF11; HIVEP2; ILF2; EHMT2; FOXM1; BCL3; ERBB4; NR4A2; TBX3; ZBED2; ETS2; KDM5D; JUNB; MEIS1; MEIS2; TGFB1I1; HDAC9; CTBP1; CERS6; MNDA; ZNF532; TRIM29; INSR; CREB3L2; PIR; HOXB2; EMX2; JUND; EHF; MYCL; SHOX2; MAF
Down-regulation	160	HMGA2; CCNH; TBP; PPARG; MED1; SUV39H1; BTG1; HEY1; ORC2; SOX15; ATF1; CCNA2; TCERG1; REXO4; VGLL4; CBFB; MTDH; ADRB2; YWHAB; KAT7; AATF; NUP62; GABPA; TADA2A; DNAJC1; PTTG1; NCOA4; PURA; ZNF672; PSPC1; TOB1; ZNF692; NFKBIB; ELF1; TP53; TMF1; TAF10; SP110; ZBTB25; PAX9; MYB; KAT6B; TSC22D4; ID3; CEBPZ; ARID4B; NRIP1; BIRC2; KDM2A; EED; IRX4; ASH2L; ASCL1; TAF1D; SOX4; NFRKB; PITX1; NR2F2; STAT6; SFMBT1; MAGED1; BRD8; WWTR1; PDLIM1; NRBF2; CENPF; MSX1; TFAM; BAZ1B; SAP30; CREBZF; TAF9; GATAD2A; SMAD1; BRCA1; BCLAF1; TCF15; AFF4; MXD1; BATF3; NELFB; SUZ12; ARNTL; JARID2; MED7; TULP4; XBP1; ENO1; LHX6; CCNT1; SMAD7; HLTF; ZKSCAN1; PITX2; NPM1; STAT3; SIRT2; FOXJ3; TBPL1; CTR9; CDK9; ZBTB43; ATF7IP; HTATIP2; NR1I2; TOX; DDX5; MLXIPL; CEBPG; HOXA7; PHF8; HOXC6; RUNX1; ARNTL2; ECD; CCNC; ID1; MED24; ZBTB24; ZFP36L2; BAZ1A; PRRX2; TSC22D2; SMAD5; ZHX2; WWP1; TSC22D1; IRF8; FOSL2; BCL11B; BHLHE40; HDAC1; YAP1; FOXD1; RB1; SMARCA2; RBM39; SP140L; TOX3; ETV1; SMAD3; ZFHX4; NAB1; LPIN2; IFI16; CRY1; NFIB; ZNF146; AHR; ZEB2; BASP1; HSBP1; SOX9; KLF10; HMGB3; MLXIP; ZBTB18; LEF1; GATA3; E2F2