Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74515	Tivozanib	GSE92742	MCF10A	Human	24h	0.4uM	EID0430

Response Information :

Types	Number	Response transcription factors
Up-regulation	72	RUNX1; HOXD1; MTDH; NFATC1; COPS5; PRRX1; NCOA6; NCOR2; ZFHX4; TOB1; AEBP1; FOXA2; STAT6; TRPS1; HEY1; EYA1; NKX3-1; ETS2; SIM2; LMCD1; SATB2; DLX5; CARHSP1; ASH2L; CHD3; PLAGL2; KDM5D; NCOA3; PURA; RARA; TWIST1; RB1; BHLHE40; SMARCB1; MBD2; NCOA2; PRPF6; STAT5A; NFX1; TCF7; MAFB; CBFA2T3; PRKDC; LEF1; ASCL1; TSG101; SERTAD2; PHF20; CENPF; EYA2; SNAI2; KLF9; FOXF2; FOXN3; FOXF1; NPAS2; BMI1; DACH1; SMARCD3; RBM39; ERBB4; NR4A1; EGR3; KLF6; VPS72; EGR1; SMAD2; BCL11A; MECOM; MEIS1; BHLHE41; PSMD9
Down-regulation	74	FHL2; NR2F6; USP22; DNMT3B; NANOG; PEG3; ZNF292; ZNF14; ZNF248; ZKSCAN5; LIN28A; SP3; PIAS1; MAGED1; NR5A2; ZNF148; ZNF23; WT1; MYNN; CCNC; ZNF571; TCF25; ZBTB3; POU5F1B; TERF1; BBX; YBX3; HDAC9; HOXB6; ZNF184; ZNF573; XRCC6; ZNF654; SALL2; RORA; ZNF529; SMAD1; TGIF1; ZNF43; CEBPG; ZNF329; BNC2; YEATS4; MYCN; ZNF189; MYCBP; CITED2; ZNF226; ZNF544; CBX7; HDAC2; ZNF165; IRF6; RYBP; SOX11; CTBP2; MYRF; HSF2; HOXB7; HMGA1; HMGB1; ARNT2; HMGB3; AFF1; ZBED2; POU2AF1; FOXK2; NFE2L3; HSBP1; HMGN3; PAX5; HOXB2; ZBTB20; SUZ12