Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74505	Motesanib	GSE92742	MCF10A	Human	24h	0.08uM	EID0430

Response Information :

Types	Number	Response transcription factors
Up-regulation	82	TBX2; MAZ; SMAD7; PDLIM1; ZBTB48; CHD3; DAXX; POLR2A; BRPF1; LITAF; CREM; CXXC1; RNF10; TADA3; DNAJC1; ZNF593; TOB1; RERE; TRIP4; BBX; RNF111; IRX5; EDF1; E2F3; SMAD4; PNRC1; YBX2; DNMT3B; TSC22D2; HTATIP2; INSR; CARHSP1; NCOA3; PFDN5; ZNF562; ZNF160; BHLHE40; ARID1A; ZIC1; IRF4; SIX2; FOSB; INSM1; RB1; TAF10; CITED1; SMARCD3; NCOA4; BATF3; BRD2; KLF13; DACH1; STAT3; SAP18; TCEB2; TRIP6; LMCD1; RSF1; RUNX3; ID3; ID2; FOXC1; AFF1; CHD7; AES; ATF3; PITX1; BRD4; KLF5; TLE2; HLTF; ZNF91; EYA2; AHR; ZNF652; REPIN1; ID1; TOX3; MSX1; TWIST1; HDAC2; PSMD9
Down-regulation	57	RHOA; IKBKAP; PROX1; TFEC; WT1; RUVBL1; MAGED1; SP110; MYB; ACTL6A; BPTF; HOXD1; SMARCE1; ZNF623; SUZ12; IRF8; OLIG2; AEBP1; RARA; XRCC6; MED13; HDGF; CNOT2; SP3; NR5A2; SOX2; HMGB2; THAP10; TRIB3; CERS4; PBX1; TSC22D1; NKX2-2; MAF; ANKRD1; FOXA1; ESR1; CRYM; SCAND1; TERF2; BACH2; GATA6; CENPF; ARNT2; HMGB3; JUP; TRPS1; TRIM22; EMX2; MNDA; ZFPM2; ZMYND8; PIR; SOX9; FOXO1; MYBL1; POU2AF1