Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74502	Motesanib	GSE92742	MCF10A	Human	24h	10uM	EID0430

Response Information :

Types	Number	Response transcription factors
Up-regulation	77	SUV39H1; DNMT3B; ISL1; ZNF443; EYA1; BRPF1; NR2F1; DLX4; TCF7L1; DAXX; KLF2; GATA2; STAT6; ZNF274; SMARCA1; CUX2; SERTAD2; MYT1L; ZNF576; TEAD4; CARHSP1; ZNF337; RREB1; ZNF629; PBX1; SMARCD2; ZNF3; LITAF; TLE2; SOX11; ZBTB24; AR; CNBP; PSMC3IP; AES; TGFB1; FOSB; DDX5; CRYM; BBX; NFIC; ETS2; SRF; INSM1; ZNF264; NEUROD1; ZFHX3; ELF4; SMARCD3; HSBP1; TFDP2; BRD4; TSC22D2; PCGF2; EED; ZNF516; AFF1; TFAP2C; PLAGL1; PBX3; PITX1; OSR2; EGR3; SNAI2; SHOX2; ID4; ZFP36L2; MEIS2; EHF; ESR1; HOXB2; PEG3; ZBTB18; ID1; ARNT2; HDAC2; MYCBP
Down-regulation	98	TFAP2A; TP53; TAF5; UBE2L3; NCOA2; DNAJC2; ARNTL; MYB; BANP; MED13; ZNF217; ZNF14; TULP4; HOXD1; TRPS1; NR1H4; TLE4; THRAP3; ARID4A; HBP1; SNW1; PHF1; RAN; ZNF184; PMS1; PRDM4; CREB5; TFAM; ING3; AATF; SP140L; NCOR2; TRIP11; BRD8; FLI1; RUNX1; SP3; CIITA; CEBPG; PURA; BCLAF1; SUZ12; CDC5L; BATF3; SATB2; KDM2A; DDIT3; SOX10; CCDC59; KMT2A; MYNN; PSMD9; IRF8; IRX4; RSF1; USP16; HMGB3; SMAD1; CHD1; NAB1; BMI1; MLXIP; ZHX2; FOXN3; PTTG1; SCAND1; ERBB4; CENPF; MKL2; TFEC; ZFPM2; ELF5; PSMC3; SMAD2; ASCL1; CHD9; CBX3; VPS72; ENO1; TOX; EN1; MEOX1; ZEB2; C1QBP; MED1; MXI1; HTATIP2; TBL1X; HOXC6; BHLHE41; LYL1; TCF4; POU2AF1; MAF; JUP; DACH1; ID2; MEF2C