Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74489	Vemurafenib	GSE92742	MCF10A	Human	24h	0.4uM	EID0429

Response Information :

Types	Number	Response transcription factors
Up-regulation	164	NFKB2; DAXX; E2F2; ID2; TBX2; NFE2L3; BCL11A; RARG; NFE2L2; SERTAD2; STAT2; ARID5B; ZXDC; DLX5; ZNF124; ETV5; SUPT4H1; WNT4; CBX2; ZNF467; PAX8; EYA1; MNDA; TCFL5; SHOX; PRDM14; AR; JAK2; CREM; PRRX2; ZFHX4; SOX5; MDM2; TRPS1; SP3; PAX1; ZNF329; CBX7; ZNF148; SMARCA1; TBX3; GRHL2; HNF1A; MXD1; CSDC2; CBX4; PBX2; VGLL1; POU2F1; MYRF; ZNF264; TP73; HOXD3; ZNF239; DLX4; NR4A2; TEAD3; ZZZ3; TAF12; ERBB4; TBL1X; ERCC3; ARHGAP35; HMGXB4; NPAS2; SIAH2; ZNF215; ELF3; TFAP2A; TBL1XR1; ZNF423; GATA1; SOX11; PRMT2; ID4; RING1; YEATS2; SALL1; SMARCD3; GFI1B; PCGF3; NR1H4; HOXB5; HOXB2; HDAC4; URI1; SSBP3; ZBED1; TCF7L1; RXRG; ARL2BP; ZNF611; PHIP; MECP2; HOXD1; POU4F1; NCOA2; MYB; HLF; TGIF1; HMGA2; OSR2; CHD9; JUN; OLIG2; ZNF331; ZFHX3; SMAD6; ESR1; TDP2; CARHSP1; CREB3L2; BANP; GTF2IRD1; SP140L; ZNF586; FOXF2; AHR; KLF11; BNC2; DACH1; BACH1; OVOL2; FOXE1; PLAGL1; ZNF160; ZNF512B; TSG101; REPIN1; SUMO1; E2F6; TFDP2; CTNNB1; PEG3; PRDM12; TBX21; ZEB1; TCF4; ILF2; RBPJ; ZFPM2; TGFB1I1; NR4A3; FOXA1; MYBL1; ZNF652; NCOA1; ZNF117; HOXC10; KAT2B; HMGB2; TFAP2C; REL; EDF1; NFAT5; FOXF1; TCEA2; ARNT2; HMGN3; FOXC1; HOXB6; ATF3; WT1; MEIS2
Down-regulation	238	THAP11; SMAD1; TLE1; ETV1; RHOA; ZNF432; TAF4; NFATC3; HDAC6; CDK8; KDM5B; CAPN15; BRD8; BAZ1A; TCERG1; SOX4; ASXL1; PBX1; MLXIP; GMEB2; PPARG; CNOT2; HMGB3; YAF2; UIMC1; USF2; MED1; CRY1; ZBED4; ATF5; MAGED1; CREBZF; ZNF672; CCNC; CREBL2; KMT2B; MAZ; NCOR2; FOSL1; TBP; CBFB; TFAM; DDX5; RBM14; KAT8; ZFX; PPARGC1A; ZNF302; BLM; CEBPA; TTF2; ERCC2; ZNF574; ARID5A; ZNF177; ARNTL; JARID2; MED21; PHF2; VGLL4; NRBF2; YBX3; TAF9B; GABPB1; HIPK3; TAF9; MTA1; KLF7; PPRC1; TSC22D2; ASCL1; PDLIM1; ZNF764; YAP1; NR2E1; SMAD3; KDM2A; ZBTB24; ADRB2; WDHD1; SUB1; ZNF226; MKL1; PSMC3IP; NUP62; ZNF222; UBE2I; ZKSCAN5; TDRD3; PHF8; PAX5; NFIB; ZNF227; EGR1; BLZF1; ATF1; NR1I2; SAP18; TEAD1; TRAK1; ZNF32; MBD4; YEATS4; RERE; HSF2; SMARCD2; ZNF384; GATA6; FOXD1; SREBF1; RUVBL2; ELF4; KAT2A; BCOR; BRPF1; BRIP1; STAT6; BATF3; SMAD5; TAF10; TAF5; MYT1L; MAK; RYBP; TGFB1; RLF; CASZ1; HCFC2; MED24; FLNA; MMS19; CEBPD; BASP1; LPIN2; MAFF; BTAF1; ZNF266; EED; TFCP2L1; POU3F2; NR1H3; JUNB; PIAS2; EZH2; ZNF131; MEF2A; TAF1D; MED7; SOX15; KAT6B; SALL2; MNT; ERG; ZNF468; TFEB; HMBOX1; SMAD7; INSR; ZNF23; SPEN; UBE2L3; PTRF; PTTG1; NRIP1; TMF1; HMGA1; PURA; MITF; ZBTB1; POLR2A; RXRA; XRCC6; CUX1; CITED1; RFX7; CARM1; RBM39; LITAF; CHD7; RNF14; ZMYND8; RUNX3; DLX2; CRK; ZBTB16; ERBB2; RBL2; EGR2; PRKDC; TOX; SAP30; ID3; ZNF528; SMARCB1; AEBP1; ZNF85; HIPK1; ZNF532; HTATIP2; ZNF91; C1QBP; HIVEP2; ING3; TRIP6; HOXC6; KDM5D; AFF1; TLE4; ZFP36L2; ELK3; CTR9; TOX3; AGO2; HDAC9; PBX3; HEY1; RORA; KLF9; BCL11B; MSX1; BMI1; BCL3; KLF4; TWIST1; PIR; BRCA1; ST18; EMX2; HOXB7; SPIB; ETS2; FOXN3; FOXG1; KLF5; NKX3-1; LEF1; RELB; NR3C1