Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74488	Vemurafenib	GSE92742	MCF10A	Human	24h	2uM	EID0429

Response Information :

Types	Number	Response transcription factors
Up-regulation	101	MEF2C; TBP; GATA2; NFKB2; DAXX; ZMIZ1; STAT4; HHEX; THAP11; RSF1; SSBP3; ARID5B; BCL11A; SOX11; SOX12; NFE2L2; MDM2; TAF11; FOXK2; ZNF239; NR2F2; TFAP2A; CARHSP1; MYCL; CBFA2T3; CREB3L2; ZNF33B; SMAD4; FOXE1; HMG20A; TAL1; CUX2; TCF4; CHD9; PAX8; ZZZ3; RBBP8; TULP4; KLF1; ZBED1; RREB1; SIM1; FLI1; ZFP69B; SETDB1; RFC1; HOXB2; TCF7L1; TRPS1; MNDA; CDK2; PHF1; SSBP2; HBP1; RBPJ; HMGA1; SP3; ZNF611; AR; MYBL1; TERF1; NFE2; ZNF512B; TBX3; ZFPM2; MED23; COPS2; AES; ZNF93; NR4A2; JUN; TCF7L2; ID4; NPAT; ZNF331; RNF111; PBX3; TEAD4; WT1; PNRC1; ZNF117; TBL1XR1; ZNF43; TBL1X; DACH1; ZEB1; BHLHE41; AFF1; ISL1; NR2F1; CRYM; FOXN3; PHIP; ARNT2; INSR; CITED2; SMARCA1; TFAP2C; ESR1; PEG3; MEIS2
Down-regulation	129	RUVBL1; NR2F6; CREB1; SAP18; TAF9; AATF; HOXA1; FOSL1; RNF6; MLX; EN2; ZHX3; SUV39H1; ADRB2; MED1; DDX5; HMBOX1; JUNB; RUVBL2; GATA4; MSX1; PGR; IRF7; INSM1; MAGED1; TSC22D2; KLF7; SMAD5; NR1I2; PURA; SOX15; PPARG; MITF; ATF5; CNBP; SOX4; JARID2; TOB1; ZNF536; TEAD1; ZNF222; HTATIP2; CEBPD; ZNF177; RNF141; ZNF516; FOXA2; LMCD1; CASZ1; RBBP7; BTG1; BATF; PROX1; RBL2; BAZ1A; KLF10; ARNTL; POU3F2; ING2; HOXC4; MAFF; ZMIZ2; MAZ; HOXB7; EGR1; BCL3; NUP62; ELF1; STAT6; PAX5; ING1; FOXO1; ZNF23; ERF; TGIF1; CBX3; ZNF562; NR2E1; EGR3; EGR4; MYRF; CHD4; ZBTB1; MTDH; ZBTB18; TAF10; PTTG1; FLNA; HEY1; VEZF1; TCF7; EGR2; MTA1; SMAD1; PPRC1; SNAI2; FOXD1; SPIB; NCOR2; TRAK1; ASCL1; NR4A1; ID3; KLF9; PDLIM1; FOSB; SMARCD2; ZNF302; KLF4; ZIC1; CRY1; PRKDC; TWIST1; TSC22D1; FOXG1; NKX2-2; HMGB1; TOX; BRCA1; EHF; KLF6; CARM1; MYB; RUNX3; BMI1; MAF; TLE4; RELB; NR3C1