Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74487	Vemurafenib	GSE92742	MCF10A	Human	24h	10uM	EID0429

Response Information :

Types	Number	Response transcription factors
Up-regulation	138	PPARD; DAXX; NFKB2; E2F2; MDM2; TRPS1; TCF25; NFE2L2; SUPT5H; CBX4; PKNOX1; SATB1; NKX2-1; ZNF345; ETV5; TEAD3; RING1; DLX5; SOX5; RNF10; ESR1; OSR2; CREM; ERCC3; PHF1; PRDM1; ZNF682; TFAP2A; RARG; CBX7; SCAI; PAX8; ERBB4; ZNF239; PBX2; SUPT3H; ID4; BCL6; MNDA; ZNF331; SCMH1; TCF7L1; GRHL2; XBP1; ZNF362; ZNF33B; ZNF512B; ZXDC; ZNF444; BHLHE41; BARX1; MECOM; STAT2; ZNF22; MYCL; ZNF248; CRYM; TGFB1I1; TLE2; SIAH2; RREB1; ZNF148; VGLL1; ZNF117; CSDC2; ZSCAN31; ZBED1; ZNF623; ZNF423; ZNF136; NFYA; RBPJ; REL; MEIS1; HOXA5; IRF9; ZNF12; SPDEF; URI1; CCNE1; NR2C1; ZFP69B; SMARCA1; NFKB1; BRD2; PHIP; MYBL1; IRF7; SP140L; TSC22D3; ZNF467; FOXA1; WNT4; NFAT5; HOXB2; ZNF586; SSBP2; NR4A3; ZKSCAN4; MED23; SP3; JUN; IRF6; TBL1X; ELF5; PAWR; FOXF2; HIVEP1; PEX14; ZFHX3; KMT2A; SP100; ZHX2; SALL1; ZFPM2; TBX3; CREB3L2; TCEA2; JUP; EDF1; HOXD1; HMGA2; TXNIP; ZNF83; AR; RORA; PHF20; ARNT2; HMGA1; ELF3; MAFB; TRIB3; SOX17; NR4A2; FOXF1; MEIS2; TOX3; WT1
Down-regulation	214	THAP11; SMAD1; ZNF432; CREB1; AATF; CBFB; TBP; ATF1; SUV39H1; CENPB; JUNB; ZNF532; SIM2; FOS; CCNA2; MED1; TAF4; TCF3; PPARG; ATF5; HTATIP2; TCERG1; SFPQ; ZBED4; NUP62; MLX; SAFB; SCAND1; PPARGC1A; TSC22D2; ETV1; SOX12; ZNF143; VGLL4; MAGED1; POLR3F; NCOA6; ARID4B; ZNF133; CREBZF; EP400; PEX2; ASH2L; HAND1; CAPN15; HOXA4; TSC22D4; EED; NR1I2; CTR9; ELK1; SAP30; CDX2; HMBOX1; PCGF2; ZNF222; ZFP64; TAF10; ID3; ADRB2; PSMC3IP; ZNF672; STAT3; NR1H2; NCOR2; HEY1; RUVBL2; EGR2; SOX15; USP22; NFIB; PMF1; LHX1; ELF1; TEAD1; ADNP2; GATA4; BRPF1; KDM2A; ALX1; EGR1; TFCP2; SUB1; SMAD3; PDLIM1; YWHAB; YAF2; PHF8; HIPK3; KAT6B; THAP1; BIRC2; DDX5; BHLHE40; TMF1; CEBPD; NFIX; TRAK1; BLM; PAX5; BRCA1; VEZF1; FOSL1; BACH2; CBX3; FOSB; BATF; C1QBP; ZBTB18; TRAF6; SMAD5; MTA1; MYF6; ZNF45; SOX9; KLF6; ZBTB1; MAZ; ASCL1; RNF6; RBM14; SMARCA2; LMCD1; ZEB2; TGFB1; CRY1; TLE1; BRD3; BMI1; CRK; BRD8; FOXD1; TFEB; ZBTB7A; KAT6A; NRBF2; SPIB; BAZ1A; ING3; ZNF177; JARID2; ZBTB25; CITED1; ATF3; RCOR3; EP300; PATZ1; BATF3; PRKDC; HOXC4; HNRNPD; ZNF23; NR2E1; ERBB2; PIAS2; GTF3A; CARM1; KLF10; RXRA; ZNF281; TWIST1; ZMYM2; RFX7; KAT7; TOB1; ZNF266; MED24; AFF1; HDAC9; SAFB2; ELK3; ZNF32; MTF2; HSBP1; HIC2; FLNA; KLF7; MITF; MAFG; HMGB2; BCL11B; KLF2; PURA; ERG; NCOA4; WHSC1; ZNF302; RUNX3; ARNTL; HOXB7; CHD7; SMARCD2; ZFP36L2; HOXC6; POU3F2; FOXG1; YAP1; ING2; BCL3; BASP1; MEOX2; TRIP6; MNT; BRD4; STAT1; KLF9; TLE4; NAB1; TP63; HOXB6; IRF4; EGR3; RELB; NR3C1