Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74484	Cgp-60474	GSE92742	MCF10A	Human	24h	0.4uM	EID0429

Response Information :

Types	Number	Response transcription factors
Up-regulation	256	MDM2; TBX2; GLI2; ZNF345; PPARG; IRF9; ZNF419; TBX1; MYCL; TAF11; KLF13; SHOX2; TFAP2A; NFATC3; PHF1; ZNF580; TRPS1; ZNF154; ZNF136; PRDM14; ZNF350; SSBP2; ZNF264; ZNF132; ARID5B; ZNF134; SALL2; TAF1C; ZNF586; RING1; BNC2; SOX3; PRDM1; RARG; CREB1; ZNF304; IRF7; THRB; ZNF331; ZIC3; ZNF423; CIR1; VPS72; NFATC4; CDIP1; CUX2; ZNF211; ZSCAN9; SPDEF; ZNF665; SOX17; ZFPM2; SP140L; ZNF623; CBX2; CBX7; NHLH2; ZNF587; LHX3; DRAP1; CBX4; ATF3; ESR1; EMX2; TBX6; CNOT3; HOXA3; TWIST1; TAL1; ZNF682; HOXB1; HOXA4; KLF3; NEUROG2; TGFB1I1; ID4; GFI1B; ALX4; ERBB4; MED14; ZNF557; FEZF2; BCL11A; HIPK2; ZNF667; ZNF394; BHLHE40; DLX5; ZNF12; CDK2; NR4A3; HDAC6; TBX5; HOXB5; RLF; ZNF91; SP100; PBX2; HBP1; WNT4; ZNF215; HLX; PRRX1; HEY1; ZNF195; KAT2B; ZNF606; SUPT6H; NR5A2; FOXL2; NR2F1; TP73; SIX6; AR; ZBTB43; EHMT2; SNAI2; ZNF235; ZNF175; PPARD; TAF6L; BARX1; CDX4; WT1; ZNF358; ZNF44; BRD2; SRY; ZNF770; ELF4; INSM1; CREB3L2; HEY2; CEBPE; MECP2; ZNF467; E4F1; ZNF500; HOXD3; ZNF768; TGFB1; TFEC; ZNF512B; TCEA2; TCF7L1; PBX3; ZNF529; ZNF148; ZFP69B; ZNF426; L3MBTL1; ZNF444; HSF1; HDAC9; ZNF552; TCF21; ZNF268; ZNF611; CERS4; MECOM; WWP1; ARID5A; ZNF329; LHX2; FOXI1; TBX3; HHEX; BRD4; SPI1; CSDE1; IRF5; PEG3; SOX13; BPTF; HOXD1; ZEB1; SUB1; TSHZ2; ZXDC; LITAF; BHLHE41; RRN3; POU2AF1; ZKSCAN4; PBX1; TFAP2C; PSMC3; ZSCAN31; RERE; ZNF14; ARNT; KAT2A; ZNF551; NR1H2; EHF; ZNF43; E2F2; OSR2; ATN1; ZSCAN18; ZNF93; TCF7L2; NR0B2; FOXN3; MXI1; PTRF; ZNF135; ZNF669; ZNF224; CERS6; TERF1; LIN28A; EN1; OVOL2; PRDM12; FOXE1; NANOG; FOXF2; NEUROD1; PEX14; EYA2; HIC2; MAFF; CD3D; TCF7; ST18; MEIS1; ZNF274; ZIC1; IRF6; CREB5; TRIB3; ZNF232; TXNIP; DACH1; MAFB; CAMTA2; MYBL1; FOXF1; ARNT2; HMGA1; MNDA; RAD21; MEIS2; SSX1; ZKSCAN1; HOXB2; FLNA; FOXO1; ID3; SMARCA1; LEF1; PIR; KDM5D; HIRA; SOX2
Down-regulation	358	CCNA2; MYC; NR2F6; SIX2; AATF; SMARCA5; CDK8; TBP; FOXO3; RBM14; CDK7; CBFB; MAGED1; SUV39H1; SMARCA4; EZH2; BAZ1B; PSPC1; CNOT1; ATF1; CBX5; HDAC2; ADRB2; GABPB1; HOXA10; RAN; RBBP4; RUVBL2; DMTF1; RFX5; ZBTB24; PMS1; BAZ2B; SAP30; CENPB; SMAD1; SAFB; BRD8; UBE2I; TSC22D1; FOXJ3; CEBPA; NCOA6; ELF1; PITX1; BRPF1; DDX54; GTF2IRD1; PKNOX1; SOX4; CEBPZ; TRIM28; KAT5; ZNF672; IKBKAP; TFCP2; CHAF1B; SFPQ; DPF2; TCFL5; PURA; ELK1; VGLL4; HOXA11; ECD; HNRNPD; SMARCD3; SMARCE1; YWHAB; NFYB; HOXA1; BAZ1A; LIMD1; TRRAP; HDAC7; NELFB; HOXC6; HES1; TSC22D2; CBX3; NFX1; KAT6A; PATZ1; ZNF292; BRD3; UIMC1; HOXA5; TRIM32; HMG20B; DNAJC1; TBL1XR1; ORC2; TCF15; KDM2A; YAF2; NRBF2; ZHX3; TBPL1; KAT7; USP22; EED; SNIP1; TLE1; RB1; NR2F2; RNF6; CTR9; PHF20; PRRX2; ZNF574; FOXN2; HOXB7; ATF6; HOXC10; PRDM4; TCERG1; TGIF1; TBL1X; POLR2A; TSC22D4; CRK; HOXC4; ATF7IP; TCF20; PITX2; MNAT1; ETV1; REXO4; ELK3; NUP62; CENPF; STAT5B; ZSCAN5A; HIPK3; TAF9; ZFHX4; XBP1; TERF2; ZNF282; CTBP2; USP21; TOB1; TMF1; ZNF410; ZBED4; MLXIPL; MGA; ZNF516; TRIP11; KLF2; MEF2A; RBBP7; MLLT10; NR1H4; MLX; CLOCK; ASXL1; BCLAF1; ZNF45; DR1; UBP1; MED4; DDX5; ZNF227; SETD3; HMGB2; LPIN2; E2F6; TAF1D; BLM; CIC; NEDD8; SETD2; NR0B1; HMG20A; TRIM27; PA2G4; WDHD1; RNF14; TADA2A; PTTG1; ZNF131; BATF3; BLZF1; ERCC3; NFYA; EP400; ZNF629; SOX9; SIX1; SMARCD2; NPAT; MXD4; NFIL3; CEBPD; ZFP64; SIAH2; PAWR; HOXA7; AFF1; NCOA4; ZNF189; TTF1; UBE2B; RNF141; HIVEP2; RNF4; PPARGC1A; SNW1; CXXC1; PLAGL2; SSRP1; AIP; FOXO4; MTF1; TCF25; ZBTB1; ETV6; NFIB; SMARCA2; MYT1L; ZNF443; HTATIP2; KMT2A; STAT4; ELF2; ELF3; MED27; SERTAD2; CRY1; SUZ12; ZNF23; ATF4; MED7; STAT6; EGR4; PMF1; IRF2; HDGF; ING2; MED1; ZNF384; KDM5B; FOXK2; ID2; TAF5; APEX1; PPRC1; JUNB; HSF2; WWC1; YBX2; HLTF; MED20; NRF1; SMAD5; ERBB2; PCGF2; TCF12; ZNF200; YAP1; BMI1; RCOR1; NPM1; ETV5; ZBTB14; CHD1; TRAK1; ESRRA; MED23; SAFB2; RFX7; ING1; THAP1; FOS; CREB3L1; HMGB1; BTAF1; RUNX1; BATF; ARID4A; ZNF202; RNF111; CEBPG; CCNC; TSG101; XRCC6; ARID4B; ZBTB16; ADNP; ZBED1; HSBP1; DEAF1; HMGN3; DEK; FOXC1; PIAS2; MMS19; CHD3; ATF5; SREBF1; TLE2; SFMBT1; NAB1; NRIP1; ASH2L; JARID2; ZMYM2; ZMIZ2; MTDH; KLF6; FOXA1; MTF2; CNOT6; URI1; PHF8; RBL2; TEAD1; BRCA1; DNMT3B; NR1I2; BCL3; CITED2; GTF3A; VEZF1; TP53; ZZZ3; CHD7; BCL11B; NONO; KLF10; BASP1; POU4F1; RBPMS; NFAT5; ARNTL; TRIP6; ERG; NKX3-1; ZNF302; TRIM16; FOXD1; ISL1; WHSC1; ZBTB18; KDM5A; SPIB; YBX3; NR1H3; CARM1; SMARCC1; ZBTB20; MLXIP; IRX5; ETS2; PUF60; RELB; NR3C1