Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74475	Xmd-1150	GSE92742	MCF10A	Human	24h	0.08uM	EID0429

Response Information :

Types	Number	Response transcription factors
Up-regulation	127	SSBP2; MAGED1; EGR2; BRD2; TFDP2; PLAGL2; AEBP1; E2F8; NFIC; HMGB3; SRF; YBX2; BAZ2A; NR0B1; TOB1; MYB; PEX2; E2F5; TGS1; ZNF217; ZSCAN18; TCF12; PHF2; NR1D2; LEF1; ZNF148; ESRRA; RXRA; HDAC4; IRF5; TOPORS; DBP; VGLL4; HIC2; PHOX2B; INSR; IRF2; ZNF329; NFE2L3; CERS6; ZNF350; SKI; SERTAD2; JUNB; ID1; PLAG1; ELF5; E2F3; ARID5A; BPTF; AFF1; BHLHE41; PRKDC; KAT7; WNT4; ZNF532; GRHL2; SOX13; PHF1; ISL1; FOXA2; KLF2; TSG101; STAT5A; ZNF22; KMT2A; SOX17; MYCL; FOXI1; GATA6; ZNF354A; OSR2; MECP2; KLF4; TGIF2; MECOM; ZNF331; CHD1; ZEB1; ZFP36L2; ERBB4; LPIN2; RELB; IRF6; FOXN3; PIAS1; SMARCA2; VDR; ATF4; ING3; HIVEP2; GMNN; NFAT5; TCF7; SMAD2; CHD4; NCOR2; SMAD7; ZBTB16; KLF10; SAP130; MYBL1; BCL11B; NCOA2; SATB2; HLX; RNF14; WHSC1; SMARCD2; EHF; PBX3; CD3D; TXNIP; IFI16; SSX1; AR; HIPK1; RUNX1; SMARCA1; MEIS1; SOHLH2; PIR; IRF4; ESR1; EGR3; DACH1; MEIS2
Down-regulation	112	HMG20B; PARP1; CRK; SIX2; ZNF146; ZNF133; CAPN15; ZBTB17; TOX4; PFDN5; NPM1; NR2F2; USP21; APEX1; FUBP1; CBX5; UBE2I; MED16; CENPB; ZNF430; NELFB; NEDD8; POLR3F; CHD8; TGIF1; RAN; PITX1; TRIM28; CBFB; NR2F1; ZNF24; ZNF580; ALX1; PAX5; HOXC6; ZNF665; ZNF611; IRF8; STAT6; HLF; ZNF91; GLI3; ZNF544; RXRG; ZNF512B; IRF3; CITED2; ZNF44; TFCP2; ZNF302; GTF2I; INSM1; PATZ1; SOX9; NRIP1; SIX1; ZNF263; MED15; JUP; TRIM27; BCL6; ZNF593; NFIB; ZNF573; TRIM22; TSC22D1; ZNF224; HEY1; MED24; ZNF93; WWC1; ZNF160; ZZZ3; TRIP6; TRIM29; TLE2; ZNF426; HDAC9; CITED1; SIAH2; PPARGC1A; HOXC10; BATF; RBBP4; PLAGL1; TEAD1; MED21; CTBP2; ELK3; KAT2A; ZBTB18; GTF3A; C1QBP; PTTG1; MEOX1; TBX3; TGFB1I1; HMGA2; ZNF281; KLF6; ATF3; IL16; TRIM16; TULP3; ZNF117; LOXL2; ZNF652; NAB1; CRYM; ZKSCAN1; TOX3; NR3C1