Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74460	Torin-1	GSE92742	MCF10A	Human	24h	0.4uM	EID0429

Response Information :

Types	Number	Response transcription factors
Up-regulation	113	CEBPA; ARID5B; ZNF423; CBX4; NAB2; IRF9; TRPS1; SOX3; ZNF500; TSC22D3; KLF3; ATN1; NFATC4; CERS6; VPS72; OSR2; CALCOCO1; TGFB1I1; TCF25; CREBL2; PHF1; ZNF12; ZNF768; PFDN5; SSBP2; SRCAP; CNOT2; RING1; SETDB1; ZNF33B; BTG1; LZTR1; STAT6; BPTF; TCF7L1; ZNF354A; ARL2BP; EMX2; PRDM1; ZFHX3; HBP1; PBXIP1; NKX2-1; NRIP1; ZNF623; ZNF444; EN1; CSDE1; CUX2; ZFP36L2; ZNF350; SNAI2; INSM1; MYBL1; ERBB4; LITAF; ESR1; KLF13; ARID1A; RYBP; HSF1; HOXD1; PAWR; SHOX2; ZNF91; SUPT3H; IRF6; NEUROD1; SP100; CTBP2; ZNF22; ZNF415; MED13; SOX11; ID4; TDP2; TCEA2; CUX1; KLF10; MECOM; INSR; TRIB3; FOXF2; ARNT2; ZNF43; ZHX2; ST18; JUP; ZKSCAN1; HMGA1; POU2AF1; GATA6; KLF7; SOX17; ZIC1; MTA1; PEG3; NCOR2; ZNF83; TP53; HDAC9; ERBB2; ZSCAN18; TBX3; ZFPM2; CRYM; TWIST1; SMARCA1; MXI1; FHL2; DACH1; PBX3; TXNIP
Down-regulation	140	CCNA2; MYCBP; SUV39H1; TBP; CBFB; FOS; SMARCA5; RBM14; TFDP1; ETV1; RUVBL2; HMGB2; PARP1; ZNF184; NUP62; ZNF227; YWHAB; NELFB; NFKBIB; KDM2A; ZNF45; AATF; EED; TADA2A; ATF1; ATF6; BRPF1; STAT3; KAT7; DR1; GTF2A2; PTTG1; ZNF672; WDHD1; HLTF; PPARG; CTR9; HMG20A; HNRNPD; ENO1; NFX1; TAF9B; BLM; CENPF; ORC2; RBBP7; FOXM1; SMARCA2; PITX1; ZBTB38; ZNF200; SFPQ; XBP1; GTF2I; RFX5; RBL1; BATF; GABPA; VGLL4; HOXA10; TRIM32; SMARCA4; RHOA; RNF4; ALX1; NR1H2; SMAD1; NRBF2; ASH2L; PSMC3IP; BRCA1; PIR; BCL6; C1QBP; WWC1; HSF2; ELF1; DNMT3B; ECD; MEF2A; BATF3; SMAD5; MED1; NR1D2; TBPL1; NFIB; RNF141; CRY1; PHF8; TRIP6; NAB1; HOXB7; BAZ1A; CITED1; ARID4B; BMI1; CBX3; HOXC6; BCLAF1; BRD3; RNF6; MTF2; RBBP4; HMGN3; SUB1; PPARGC1A; JARID2; BCL3; POLR2A; CCNT1; PURA; RFX7; XRCC6; RNF111; CHD7; SAP30; CHD1; ING3; ELK3; ZNF23; ZBTB18; TRIM16; FOSB; BBX; RUNX3; SMARCD2; ZEB2; AFF1; ELF3; NR4A1; IFI16; ING2; IRF4; FOXC1; RBPMS; ZBED2; HTATIP2; PSIP1; NKX3-1; KDM5D