Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74459	Torin-1	GSE92742	MCF10A	Human	24h	2uM	EID0429

Response Information :

Types	Number	Response transcription factors
Up-regulation	115	ELF4; KLF3; CALCOCO1; CBX7; CBFA2T2; TSC22D3; ST18; TFAP2A; HOXB13; JUP; RARG; CBX4; TGFB1I1; GATA6; NFATC4; SRCAP; TCF25; CDIP1; LZTR1; VPS72; ZNF500; HDAC5; ING4; SSBP3; PCGF3; MZF1; HOXD1; ZNF358; KLF7; INSM1; SHOX2; IRF9; OSR2; ZNF215; ERBB4; CBFA2T3; DLX5; EN1; HSF1; ZNF623; ZFPM2; SETDB1; MED15; KLF13; ZNF580; NHLH2; ZNF74; PEX14; ZNF532; ZNF350; ZNF354A; OVOL2; WWP1; ZBED1; PBXIP1; ZNF444; ARL2BP; TRPS1; HDAC9; HBP1; SOX4; ZNF217; FOXF2; ZFHX3; ATF3; PRDM2; SMAD4; ZSCAN18; NEUROD1; PAWR; ZNF232; IRF6; ZNF12; ZNF83; ARID1A; TCF7L2; KAT2A; BHLHE41; SNAI2; ZNF91; MAFF; TRIB3; BRWD1; KLF11; FLNA; BACH1; HIC2; PNRC1; TCEA2; ZHX2; SOX17; ARNT2; MAFG; ZNF117; ZFP36L2; HMGA1; MYRF; TCF21; HOXB2; TCEA1; MEIS1; PBX3; ZKSCAN1; MLXIP; MYBL1; ERBB2; CREG1; KLF6; PEG3; DLX2; FHL2; TWIST1; MEIS2; CITED2; HOXB6
Down-regulation	164	MYCBP; CCNA2; SUV39H1; EZH2; GTF2A2; CREB1; TFDP1; CBFB; TBP; PARP1; ITGB3BP; MAGED1; CBX5; ZBTB24; ETV1; MED1; VGLL4; GATAD2A; PSMC3IP; ATF1; HDAC2; CTR9; RFX5; RBM14; PTTG1; ZNF672; ZNF45; KDM2A; ZNF267; CHAF1B; RBBP8; RUVBL1; NFIL3; HMGN3; TFAM; TCF20; ATF6; AATF; WDHD1; EED; NUP62; YWHAB; TAF5; SMARCA5; ZBTB38; ZNF200; MYBL2; ZNF184; NR2F2; BCL6; NFKBIB; RHOA; SFPQ; NEDD8; RAN; HOXC6; GABPB1; ID1; BRPF1; ORC2; PATZ1; ADRB2; MLX; CEBPZ; HLTF; LIMD1; CCNC; CCDC59; TSC22D2; HMGB2; CLOCK; DNMT3B; SSRP1; RBL1; UBE2I; RUVBL2; CRY1; SIAH2; PPARG; KAT7; UBP1; YEATS4; SIX1; ING3; RBBP5; ING2; MNAT1; TBPL1; HOXA10; TCERG1; PSPC1; SMARCE1; CARHSP1; TP53; PURA; SUB1; TAF9; MBD2; ZNF131; ZMYND11; NELFB; BRD8; MAFB; STAT1; MED6; BAZ1B; ING1; BRCA1; POLR2A; BLM; BCOR; NR2F1; SFMBT1; SMARCA2; NLK; BATF; NCOA6; TRIP6; ECD; CENPF; KAT6B; SMAD1; PITX1; SAP30; RNF6; BCLAF1; HOXC10; ZNF22; SAFB2; ZBTB18; MTF2; XBP1; ZNF107; PIAS2; MED13; HNRNPD; BMI1; YAF2; ARID4B; RBBP7; ELF5; NCOA4; JARID2; TCEB2; C1QBP; CITED1; ZNF430; IFI16; ERG; TAF10; NFIB; TOB1; NAB1; SMARCD2; ETS2; SMAD2; RBPMS; ZNF652; ELK3; TBL1X; KLF5; PSIP1; LEF1; NR3C1