Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74356	Gw-5074	GSE92742	MCF10A	Human	24h	10uM	EID0429

Response Information :

Types	Number	Response transcription factors
Up-regulation	120	FOXO4; DAXX; TCF15; NFKB2; PKNOX1; NFE2L3; MED12; EN1; ZNF345; DLX5; SUPT5H; TRPS1; CRX; PHF1; TFAP2A; BCL10; SIX5; CBX7; TCF20; HDAC7; VGLL4; CREM; ETV7; BCL11A; CHD4; HMX1; NFE2L2; NR4A3; ZNF574; TULP4; BACH2; CEBPZ; NFKB1; CCNE1; SSBP3; USP16; ZNF331; SREBF2; NAB2; SPDEF; BARX1; HOXB13; HIVEP1; ZNF667; MEF2D; RING1; FOXE1; CDX1; ZNF33B; RNF138; TCF25; ZNF205; ZNF112; TSHZ2; ARID5B; SUPT3H; RELA; ZNF16; MYT1; RLF; PQBP1; DEK; ZXDC; ZNF623; HOXB1; ELK4; IFNB1; IRF6; PHIP; OSR2; ZHX2; EYA1; RXRG; SNAI2; MYBL1; SPI1; NFAT5; MAFF; NR4A2; AHR; MEIS1; FOXF1; TCF12; BRD2; CAMTA1; CD3D; MED13; ILF2; RBFOX2; PHF20; ZNF224; IRF8; ZFHX3; PAWR; AGO2; TRIM29; SP140; ZFPM2; ZNF512B; RELB; ERF; ID1; FOXF2; TBX3; SMAD2; NR2F1; ARNT2; HOXD1; KLF4; TCEA2; JUN; HOXB2; ZEB1; REL; MNDA; TFAP2C; BCL3; WT1; DACH1; ESR1
Down-regulation	151	CRK; CCNA2; TSC22D2; CREB1; ZNF432; BTG1; HTATIP2; MED6; RERE; CBX6; SIM2; TTF1; NELFB; POLR3F; ETV1; AATF; SOX4; RNF141; PITX1; RBBP8; MED4; MXD4; TRIM28; SIRT7; CREBZF; ZNF764; MITF; HMBOX1; MAGED1; HDAC6; ADRB2; PPARG; YWHAB; KDM2A; TBP; ASH2L; CTR9; RBBP5; NFIB; BRIP1; CNOT2; BAZ2B; KMT2B; TRIP6; NUP62; EZH2; MAZ; RBPMS; JARID2; CUX1; BRD8; NRBF2; PDLIM1; RUNX1; KAT6B; ID2; RCOR1; ZNF44; VPS72; CBX3; CNBP; MAFG; ZNF516; DDX5; C1QBP; RBM14; CNOT3; ZNF226; NR0B1; ZBTB16; GABPB1; PPARGC1A; ZEB2; TRAK1; FLNA; ZKSCAN1; EGR2; ZNF24; NR2F2; VEZF1; MEF2A; SOX15; ATF5; EED; EGR1; ERG; NCOR2; TSC22D3; PREB; MLXIP; CDK9; ZNF410; TLE1; MTA1; TAF10; PTRF; REST; ZBTB38; ZNF107; FOSB; TMF1; INSR; PAX6; SMAD1; MSX1; ZBTB18; SAP30; MLLT10; NR2E1; SMAD7; ZNF23; NFE2; HLTF; TEAD1; AEBP1; BAZ1A; BRCA1; PCGF2; ERBB2; SMAD5; CITED2; SMARCD2; BMI1; PURA; ST18; JUND; KLF7; SMARCA2; HMGN3; CITED1; WWC1; PIAS2; ING3; FOXO1; CARM1; BLM; HDAC9; SUB1; FOSL2; NKX3-1; MNT; IFI16; KDM5D; KLF2; FHL2; ZIC1; HOXC6; IRF4; IRX5; EGR3; NR3C1