Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74352	Gsk-461364	GSE92742	MCF10A	Human	24h	10uM	EID0429

Response Information :

Types	Number	Response transcription factors
Up-regulation	227	NFKB2; DAXX; STAT5B; MYBL2; CBX7; ID2; SATB1; SUPT5H; NFE2L3; PKNOX1; CREM; ETV5; ZNF184; DMTF1; BCL11A; URI1; NFE2L2; TBX2; MDM2; EED; ZBED1; ZNF423; ZNF239; PAX8; ARID5B; SOX3; ZNF257; ZKSCAN3; ID4; MED12; ZNF331; CBL; CEBPA; MGA; NR4A2; NKRF; ZNF711; MYBL1; BHLHE41; SERTAD2; FOXE1; NFIL3; ZNF43; CD3D; ZXDC; SPDEF; ZNF208; PAX6; ZNF273; ZNF253; RBPJ; CEBPZ; SUPT4H1; ZNF571; ERBB4; MYB; CDK2; ZNF141; YEATS2; TAF12; ZNF112; MEIS1; XBP1; PRRX2; PHIP; TAF1; MTF1; CIR1; STAT5A; ZNF329; TFDP2; BANP; SOX5; HOXC11; BCL6; ZNF14; PCGF3; HOXB2; HDAC7; NR4A3; ATF3; ZNF492; TEAD3; NR2F1; RREB1; STAT2; OSR2; NKX2-1; TFAP2A; TAF1A; ZNF667; ZNF124; ZNF165; E2F8; SMARCA1; ZNF136; ZNF22; ZNF443; ZNF117; CITED2; EDF1; NR3C2; ZNF93; EMX1; TBX21; RING1; HOXB3; WHSC1L1; RSF1; ZNF175; ZNF682; SP100; YBX1; SOX11; AES; MED14; ZFP69B; CREB3L2; ZNF75D; ZFPM2; CSDC2; ELF3; NFATC4; ABL1; STAT4; ZNF281; SHOX2; ZNF768; TULP4; CNOT1; HABP4; ZNF512B; ZNF33B; PHF1; REL; ZNF248; KLF2; BARX1; CIZ1; TGIF2; PRDM10; ZFP30; L3MBTL1; TCF7L1; KMT2A; SCMH1; TCF7L2; IRF1; MED17; WT1; BNC2; ARID3A; PRDM1; SUPT3H; VGLL1; CHD9; IRF6; MECOM; PIAS1; ZNF135; FOXF2; ACTL6B; TBX3; BRWD1; TGIF1; ARL2BP; POU2AF1; BRD7; ZNF430; ZZZ3; MAFF; KAT6B; TDP2; ESR1; TAF1D; TFAP2C; ATF7IP; NLK; ZBED2; HIVEP1; HMGA2; NR1H3; ZKSCAN1; NEUROD1; TERF2; ZNF85; SAP30; HOXC10; JAK2; GRHL2; KLF11; INSR; VDR; EMX2; TRIM24; KLF6; CREB3L1; SIAH2; TCEB2; ZNF573; JUN; DACH1; PBX3; ZNF611; ELF5; ETS2; ZNF415; EYA2; ZNF264; NR4A1; ZEB1; HIC2; ZFP36L2; WWC1; PHF20; ZNF652; TCEA2; MNDA; NANOG; RORA; GATA6; LIN28A; KLF4; ZNF160; ARNT2; HOXB6; MEIS2
Down-regulation	207	THAP11; FOS; MAGED1; TBP; SUV39H1; E2F1; PEX2; NRIP1; RHOA; HOXA11; SMAD1; CEBPD; ARID4B; ETV1; FOXO3; TAF4; ZBTB16; ZNF787; TCFL5; HDAC6; ZNF24; RBBP8; MYC; MTA1; MAZ; CAPN15; NFIB; BRF2; PHF2; CDK8; CITED1; DDX5; ERCC2; ASXL1; ZNF410; VPS72; POLR3F; SREBF1; MLX; CASZ1; ZNF580; ZNF432; CBFB; SRCAP; HOXA4; NR0B1; ZNF532; SUB1; ENY2; PPARG; PHF8; ATF1; ATF5; PMF1; ZNF764; HOXA10; RNF138; NCOR2; FOSL1; BATF3; MAX; POU3F1; NKX2-5; MNAT1; REST; ADRB2; ZNF211; ID3; ZNF384; MTA2; KMT5A; ZNF516; MYF6; RB1; PSIP1; ZNF212; KAT6A; MSC; BHLHE40; BRPF1; ID1; ZNF143; MKL1; SPIB; SLC2A4RG; USP22; E2F5; PCGF1; TLE4; NFE2L1; ZNF408; PAX5; BRD8; PPARGC1A; IRF2; MSX1; JARID2; HMBOX1; NFX1; PITX2; NPAS2; NRBF2; SMARCB1; HAND1; PTRF; HOXB9; SFPQ; ADNP; GABPB1; EGR1; EWSR1; ZBTB11; YAF2; ZNF672; PPRC1; TCERG1; KLF5; BRCA1; ZNF226; CTR9; KAT2A; CRY1; HEY1; MED21; MED1; C1QBP; SMAD3; SMARCD2; BAZ1A; C1D; BLZF1; ZBTB7A; CBX6; SNW1; ZBTB18; AFF4; HOXC6; BAZ1B; RBM14; ZNF587; TGFB1; TCF21; BTG1; MTDH; VEZF1; TCEA1; HTATIP2; ZFP64; ASH2L; TMF1; MBD2; FOXA2; PIAS2; KLF13; NR1H2; ZBTB43; KLF10; TLE1; AHR; RARA; SCAND1; LITAF; YBX3; LYL1; LMCD1; SMAD5; KDM5D; HOXD11; SMAD7; SMAD4; TRIP6; ERBB2; NAB1; HSF2; MED24; TP63; FOXO1; JUNB; EHF; SMARCA2; RNF14; NKX3-1; TAF10; FOXG1; PBX1; PUF60; TRIM22; FLNA; FOXD1; BLM; ZEB2; SNAI2; ZNF131; KLF9; ARNTL; ERG; MLXIP; IL16; NCOA4; SOX17; APEX1; BMI1; TRIM16; BBX; BCL3; RELB; NR3C1