Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74325	Barasertib-hqpa	GSE92742	MCF10A	Human	24h	2uM	EID0429

Response Information :

Types	Number	Response transcription factors
Up-regulation	83	SUV39H1; ARID5B; CBX7; TFAP2A; XBP1; IRF9; AES; TAF7; SMARCC2; SSBP2; PRDM1; BCL11A; ATN1; SOX13; CUX2; SETDB1; ERBB4; POU2AF1; CDK2; ZNF512B; ZNF586; SSBP3; HHEX; CALR; DLX4; TRIM22; SALL2; ILF2; ZNF12; NKX2-1; PIAS4; ZNF93; CNOT3; FOXF2; IFI16; TLE2; VPS72; LIN28A; SP100; HOXD1; CREB3L2; JUP; TCEA2; BRD7; ZNF91; RBPMS; SHOX2; TRPS1; TDP2; CD3D; SOX17; ZNF544; TGFB1; TBX3; ZNF551; TRIB3; PHIP; ZSCAN18; ARNT2; ST18; MYBL1; INSM1; MECOM; ZNF331; SMARCA1; ZEB1; ZBED2; RAD21; ZNF117; HDAC9; HOXB2; CITED2; ZFP36L2; BHLHE41; FOXF1; TFAP2C; ATF3; ZKSCAN1; MYRF; NKX2-2; ZFPM2; MEIS2; ESR1
Down-regulation	76	CCNA2; TLE1; LIMD1; MAGED1; NR2F2; HMGB2; EZH2; CEBPA; CREB3L1; SOX4; RUVBL2; NUP62; CBX6; SKI; RUNX1; TMF1; CEBPD; ATF1; MEF2A; FOXD1; ZNF516; MBD2; BTG1; MSX1; ATF5; PTTG1; SMAD1; KDM2A; CTR9; SIAH2; HSF2; MAX; KLF2; TBL1X; LPIN2; ZNF23; MED1; PURA; BCL6; PAWR; HOXC6; SREBF1; BAZ1A; HNRNPD; WHSC1; RXRA; ING2; ING1; BHLHE40; TBPL1; FOXC1; ZEB2; HMGB3; ZBTB38; BATF3; KLF5; SMARCA2; NFAT5; ERG; SAP30; HLTF; YBX3; NKX3-1; PIAS2; SMAD2; ARID4A; CTBP2; FOXO1; ISL1; IRX5; BASP1; BRCA1; KLF9; LEF1; TXNIP; RELB