Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74317	Azd-6482	GSE92742	MCF10A	Human	24h	2uM	EID0429

Response Information :

Types	Number	Response transcription factors
Up-regulation	186	DAXX; NFKB2; GATA2; ZNF589; NFE2L2; NFE2L3; ZNF239; BCL11A; ZNF345; DMTF1; IKZF1; TEAD3; TGIF1; TFAP2A; PKNOX1; RARG; GCFC2; MYCL; ZSCAN9; ZFP36L1; WT1; ZNF33B; ZNF623; SMARCC2; NFATC4; ZNF112; YEATS2; ERBB4; ZNF331; CBX4; CALCOCO1; ZFPM2; KDM5D; PAX8; NR2F1; E2F5; STAT4; TBX3; USP21; BACH2; TCF7L1; PRDM1; RBBP8; NKRF; JUP; ZNF12; ZNF329; ZNF124; ID4; MYBL1; TLE2; ZNF444; CDC5L; SMARCA1; MXD3; RBFOX2; TRPS1; RING1; ATN1; VPS72; ZFHX3; ZSCAN31; PRMT2; THAP10; AR; PCGF3; PHF1; HMGXB4; ZNF75D; EYA1; ZNF22; BCL6; CBX5; VGLL1; HOXB2; HHEX; SOX11; SP3; ZNF512B; ZFHX4; SETDB1; ZNF423; GTF2IRD1; ZNF74; ZNF76; NR2C1; ISL1; ZNF580; MEIS1; ZNF304; AES; IRF9; ZNF586; SUMO1; CREM; SUPT3H; HOXB5; ID1; HMG20A; ZNF253; ZZZ3; ZNF117; FOXF1; ARID1A; ZSCAN18; E2F8; NANOG; JUN; ZFP30; HOXA5; SMAD6; ZNF268; HOXD1; PRDM12; AHR; GRHL2; ZNF264; DEK; USP16; EN1; MED17; PHIP; IRF2; TBX21; BACH1; TULP4; CREB3L2; IRF6; ZNF43; SPDEF; ZKSCAN4; BNC2; MEIS2; FOXE1; CAMTA1; SP140L; PFDN5; NR4A2; ZNF467; TERF1; HOXD3; KAT2B; PLAGL1; ZNF217; PBX1; TRIM29; CCNE1; RBPJ; PEG3; ELF3; FOXF2; ZHX2; IRF1; CHD9; SAP130; TRIM22; ILF2; TFAP2C; REL; PNRC1; MECOM; HIVEP1; CD3D; ATF3; TDP2; TCF4; ZNF93; ESR1; CUX1; ZBED2; TCEA2; ARNT2; NFAT5; CITED2; ELF5; TRIB3; HIRA; RORA; SOHLH2; MNDA; TBL1XR1; ZEB1; BHLHE41; GATA6; HOXB6; SOX2
Down-regulation	205	CRK; FOS; TLE1; TBP; GATAD2A; CBFB; FOXJ3; MED1; TAF4; SCAND1; AATF; SUV39H1; MLX; BAZ1A; ETV1; ATF1; TSC22D2; NCOR2; UIMC1; TAF10; MYCBP; MED6; EGR1; JUNB; FOSL1; ZNF143; VDR; PSMD9; SOX15; TOB1; POLR3F; ELK1; NCOA6; STAT3; SOX4; MSX1; ZNF432; PDLIM1; RNF141; DNAJC1; RBM14; FLNA; ZBED4; ZMIZ1; ZHX3; TCF7; PHF8; EGR2; CTNNB1; HSF2; PPARGC1A; YWHAB; BRPF1; RHOA; FOXO3; CAPN15; UBE2B; PSIP1; ZNF721; SMARCA2; ZBTB16; ZNF189; HTATIP2; AEBP1; HOXA10; BRD8; NFIB; MAGED1; SMAD1; FOXO1; TMF1; ELF1; VGLL4; DDX5; PSMC3IP; NRBF2; TCFL5; MTDH; TCERG1; BIRC2; RNF6; SAP18; IRF7; YAF2; TSC22D4; ADRB2; ASCL1; ZNF24; ECD; KDM2A; NR0B1; EED; BMI1; C1QBP; HOXC6; CTR9; STAT6; PPRC1; AFF4; KDM5B; BTAF1; MAZ; VEZF1; PPARG; ZBTB11; ZNF516; BCL11B; RUNX1; NUP62; ID3; CRY1; AFF1; CEBPG; NR2E1; CASZ1; TDRD3; IKZF5; THAP1; BAZ2A; IKBKAP; SOX9; SUB1; KLF6; HCFC2; CCDC59; SAP30; MXI1; ZBTB25; MAFB; FOXD1; ZMIZ2; ZNF131; PCGF2; E2F2; RXRA; TRIM16; RNF14; ERG; MEF2A; HMBOX1; JARID2; MITF; BATF3; SAFB2; TCF12; MAFF; ZMYM2; ZNF302; PIAS2; TFCP2L1; SMAD5; NR1I2; PURA; ARNTL; TFEB; PITX1; HES1; NFE2L1; SPEN; ADNP; ATF4; RCOR3; BRCA1; ZNF23; HIVEP2; ARNTL2; TBPL1; ZNF226; PRKDC; CHD7; PRRX1; RFX7; KLF7; POU2AF1; RBBP7; BLM; PTTG1; STAT1; HEY1; ZFP36L2; ASH2L; ZEB2; ZNF160; CTBP2; NKX2-2; EGR3; IFI16; ZNF32; SMARCD2; FOSB; CARM1; KLF2; MTF2; RUNX3; PAX5; PIR; NKX3-1; INSR; KLF5; TRIP6; IRX5; SATB2; LEF1; ZBTB18; NR3C1