Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID74316	Azd-6482	GSE92742	MCF10A	Human	24h	10uM	EID0429

Response Information :

Types	Number	Response transcription factors
Up-regulation	158	DAXX; NFKB2; PCGF2; NFE2L2; SSBP3; HOXB13; TBX2; TFAP2A; ZNF239; ZNF331; ZNF33B; SMARCA1; ZNF623; ZNF345; STAT4; ZXDC; DLX5; TCF7L1; CBX5; ZNF467; ETV5; CDK2; BARX1; ZNF22; ZFPM2; ZNF586; SPDEF; URI1; PRDM1; SMARCC2; ZNF124; ZNF512B; PRMT2; OSR2; THAP10; CSDC2; CREB3L2; ZNF43; CBX7; NFE2L3; ZNF257; ERBB4; BCL11A; CALCOCO1; RBPJ; ESRRG; TEAD3; TAF12; SOX11; YEATS2; CBX4; EZH1; RING1; WT1; HOXD1; UBTF; TBX21; NR4A2; ZNF268; MECOM; ZNF329; AR; EYA1; MYCL; MEIS1; USP16; SSBP2; TCF25; ZNF74; ZZZ3; SCMH1; TGFB1I1; ARID5B; TOPORS; WNT4; HOXD3; GRHL2; IRF6; PBX2; L3MBTL1; ZNF12; SETDB1; KLF1; THRA; ZNF117; AHR; NFYB; FOXF1; TBX3; FOXA1; TFDP2; ZNF112; JAK2; TRPS1; ACTL6B; IRF9; ZNF273; MYBL1; PEG3; KLF11; ZNF667; FOXF2; EHMT2; PBX3; PHIP; AIP; CSDE1; ZNF423; BHLHE41; TCEA2; MNDA; TERF1; SP100; KAT2B; HOXB2; TLE2; NR2F1; CHD4; JUN; ZNF93; SIX3; CAMTA1; ZNF415; PRDM2; ZNF91; MXI1; CREB3L1; RBFOX2; CD3D; ZEB1; ZFHX3; PAX8; KMT2A; NR2F2; PIAS1; HSF1; AES; ELF3; ZNF544; MEIS2; ZNF551; ZSCAN18; HDAC9; ID4; ARNT2; MYCN; MYRF; TCF7L2; ISL1; TOX3; KLF6; TFAP2C; DACH1; TBL1X; CRYM; REL; HIRA; HOXB6
Down-regulation	199	THAP11; TBP; FOSL1; RHOA; TSC22D2; ETV1; CCNA2; ATF1; SUV39H1; SMAD1; CCNC; HTATIP2; FOXO1; BAZ2B; NEDD8; ZNF267; UIMC1; GABPB1; MYCBP; DDX5; MLX; MAZ; BRD8; GTF2A1; NRBF2; RBM14; MKL1; POLR3F; PHF8; WDHD1; NUP62; ZNF672; TAF10; BAZ1B; ADRB2; CTR9; ZNF432; ZNF143; NCOR2; SAFB2; SOX4; ARID4B; MEF2A; PDLIM1; MLXIPL; HOXA11; NFKBIB; BHLHE40; TCERG1; MYBL2; MED6; RUVBL2; KMT2B; CRY1; TSC22D4; GATAD2A; GABPA; PHF2; CEBPD; CAPN15; PPARG; BAZ1A; PEX2; ZBTB38; RNF141; HSF2; TTF2; SIRT7; CEBPA; EED; USP22; KAT6B; UBP1; RXRA; ELK1; TAF4; POU5F1B; PSMC3IP; CDYL; BRPF1; SNW1; ADNP; CRK; ERG; NR1I2; POLR2A; ZNF410; ZNF226; TEAD1; SOX15; VDR; VGLL4; IKZF5; PAX5; PMF1; MAFB; PIAS2; AFF4; MKL2; MSX1; E2F3; ZNF24; NRF1; ING3; ZNF165; ARNTL; ZNF200; ZNF576; EGR1; GATA4; TMF1; ZMYM2; ASH2L; SMAD5; JARID2; HOXA1; SMARCA2; ID3; FOXG1; KDM2A; REST; ELF4; MED7; BMI1; PITX1; VEZF1; IKBKAP; SCAND1; ZNF131; NR2E1; BATF3; TOB1; C1QBP; TSC22D1; CHD1; BTAF1; SMAD7; EWSR1; NCOA4; ZNF721; ORC2; HOXC6; PTTG1; RUNX1; MLXIP; CREB5; STAT6; RNF6; BATF; ZBTB18; C1D; ARID4A; BRCA1; SF1; EGR2; TRIP6; ERBB2; XBP1; HMGB3; JUND; CBX3; ELF1; SMARCD2; SUB1; TERF2; ZNF528; HEY1; PRKDC; BTG1; POU3F2; RBPMS; TWIST1; TOX; FOSB; ZNF23; TRAK1; SPIB; HCFC2; NFIB; BCL11B; POU2AF1; KLF2; FOXD1; MAFG; LMCD1; PURA; CTBP2; AEBP1; AFF1; SAP30; TLE4; NAB1; SATB2; ASCL1; DLX2; EGR3; ETS2; FHL2; NR3C1