Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID74279 Hdac3-selective GSE92742 HA1E Human 6h 5uM EID0428
Types Number Response transcription factors
Up-regulation 67 NCOA3; MED14; WWP1; CREB3; NR4A2; UBE2B; KLF9; NR2F1; DLX2; ELK4; TAL1; RREB1; TBX2; ZNF131; SMAD4; VDR; TOB1; ZNF24; CCNH; NFYB; TFAP2C; PQBP1; NR0B1; SOX9; SOHLH2; CREM; KLF5; TRIB3; MAFB; MBD2; ZFPM2; E2F8; HHEX; RBBP8; HMGA1; ETS1; JUP; FOXC1; TGIF1; FOXF1; SOX17; SAP30; INSR; TOX3; LEF1; TOPORS; ERBB4; ASCL1; SMAD3; POU4F1; DACH1; PMS1; NPAS2; IRF6; AFF1; TFDP1; NFE2L2; EHF; MYBL1; SHOX2; HOXD1; ST18; MEIS1; MTF2; HOXB2; TRIM22; CDK7
Down-regulation 82 KAT5; ZNF282; SUPT5H; SUV39H1; MED24; SMARCA4; MED16; BRPF1; MSC; ZNF787; HOXA7; MNT; SIX2; EHMT2; SSRP1; MAZ; ZNF8; TRIM28; TADA3; ATF5; RUVBL2; NELFB; KDM5D; AIP; APEX1; CHD3; CHD8; YBX1; HDAC4; PIAS3; MTA2; DEAF1; RELB; ZMIZ1; PUF60; BCL3; DRAP1; CREB3L2; PCGF2; HOXA5; ZFHX4; TAF10; SIX3; RXRA; RBPMS; CREB3L1; PTTG1; BATF3; CENPB; REPIN1; DNMT3B; MAGED1; KDM2A; WWTR1; BHLHE40; JUND; TCF4; SMARCD2; ZNF148; EYA1; GATA3; PAX8; BRD4; MED1; NR1H2; TBP; ID2; ZBTB18; IRF4; MYCN; HIRA; THAP11; HLTF; TLE4; FOSL2; WT1; PITX1; ZEB2; CEBPA; PLAGL1; TLE1; TRIP6