Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID74172 Tubastatin-a GSE92742 HA1E Human 24h 10uM EID0425
Types Number Response transcription factors
Up-regulation 57 KAT6A; BCL11B; NFKBIB; VDR; MDM2; SOHLH2; NR0B1; MAGED1; RBBP8; PFDN5; ZNF580; NKX2-2; SSX1; TCF7; ZBED2; TAF10; ZNF444; FOXI1; HMGA1; ZNF593; ZMIZ2; THAP7; MYCL; RORA; ZNF415; ESR1; OLIG2; HOXC10; CNOT3; SATB1; CREB3L1; HIRA; TRIM28; SMAD7; TRPS1; NKX2-1; OSR2; AES; POLR2A; POU2AF1; SALL1; EN1; KLF2; TCEA2; CUX2; TWIST1; GATA2; TFAP2C; MAFB; BRD4; HOXB2; INSM1; TRIB3; SOX11; AEBP1; WT1; HOXC6
Down-regulation 76 HDAC2; PSIP1; KLF10; RYBP; GTF2A2; SUPT4H1; TBL1XR1; TAL1; NFKBIA; PAXBP1; ZMYND11; MYCN; ID1; WWTR1; PHIP; KLF11; CTBP2; RREB1; DAXX; KLF7; IRF1; KAT2B; SMARCE1; TAF11; ADNP; JAK2; TCERG1; RFX5; RHOA; MED23; TCEA1; MECOM; MED24; ZEB1; TP63; PRKDC; TFDP1; MXI1; FOXL2; RXRA; MXD1; COPS5; PDLIM1; STAT5A; KAT6B; MED13; NFKB1; SP140L; CTR9; ZNF189; APEX1; ASH2L; PTRF; KLF9; ZNF217; ZEB2; SPEN; HMGB2; ERG; CCNA2; ARID5B; IKBKAP; HLTF; NR2F1; ZNF589; VPS72; RELB; TSC22D1; MED1; FOXJ3; TOB1; MEIS2; SNAI2; ZNF131; TBP; SCAND1